Strain
Avian_EU022526
(Region: USA: Indiana; Strain: Turkey coronavirus isolate TCoV-ATCC, complete genome.; Date: 2008)
Gene
M
Description
Annotated in NCBI,
M
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGGCGGATAATTGCACACTTGATTCAGAGCATGCAGTTCTGCTTTTTAAAGAATATAATTTATTTGTAACCGCCTTCCTATTGTTTCTTACCATACTACTCCAGTATGGGTACGCAACTAGGAGTCGTGTTATTTATATACTGAAAATGATAGTGTTATGGTGCTTTTGGCCCCTTAACATTGCAGTAGGTGTAATTTCATGTATATATCCACCAAATACAGGAGGTCTTGTCGCAGCGATAATACTTACTGTGTTTGCTTGTCTTTCTTTTGTAGGTTATTGGATTCAGAGTTGTAGACTCTTTAAAAGGTGTAGGTCTTGGTGGTCTTTTAACCCCGAGTCTAGTGCCGTGGGTTCAATACTCCTTACAAATGGTCAACAATGTAATTTTTCTATAGAGAGTGTGCCTATGGTGCTTGCTCCAATTATAAAGAACGGTGTCCTTTATTGTGAGGGTCAGTGGCTTGCTAAGTGTGAACCAGACCACTTGCCTAAAGACATATTTGTATGCACACCGGATAGACGTAATATCTATCGTATGGTGCAGAAATACACTGGTGACCAAAGCGGAAATAAGAAAAGGTTTGCTACATTTATCTACGCAAAGCAGTCTGTAGACACTGGCGAGCTAGAAAGTGTAGCAACAGGAGGAAGTAGTCTTTACACATAA
Protein
MADNCTLDSEHAVLLFKEYNLFVTAFLLFLTILLQYGYATRSRVIYILKMIVLWCFWPLNIAVGVISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSCRLFKRCRSWWSFNPESSAVGSILLTNGQQCNFSIESVPMVLAPIIKNGVLYCEGQWLAKCEPDHLPKDIFVCTPDRRNIYRMVQKYTGDQSGNKKRFATFIYAKQSVDTGELESVATGGSSLYT
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the gammacoronaviruses M protein family.
Uniprot
EMBL
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
223
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
63.89163
Exp number, first 60 AAs:
34.38826
Total prob of N-in:
0.03802
POSSIBLE N-term signal
sequence
outside
1 - 19
TMhelix
20 - 39
inside
40 - 50
TMhelix
51 - 70
outside
71 - 73
TMhelix
74 - 96
inside
97 - 223
