Strain
Feline_HQ392469
(Region: Netherlands; Strain: Feline coronavirus UU40, complete genome.; Date: 22-Jan-08)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGAAGTACGTTCTTTTCATATTTGCGTGCATAATTGCATGCGTTTATGGAGAACGTTACTGTGCTATGAAAGATGACAATCCTATGTCTTGCATCAATGGCACTGACTCACAATGTCGAACCTGCTTCGAACGCGGTGATCTTATTTGGCATCTTGCTAACTGGAACTTCAGCTGGTCTGTAATATTGATTGTTTTTATAACAGTGCTACAATATGGTAGACCACAATTCAGCTGGATCGTTTATGGCATTAAAATGCTGATCATGTGGCTACTTTGGCCCATTGTTCTAGCGCTTACGATTTTTAATGCATATTCTGAGTATCAAGTTTCCAGATATGTAATGTTCGGCTTTAGTGTTGCAGGTGCAGTTATAACGTTTGCACTTTGGATGATGTATTTTGTGAGATCTATTCAGCTATATAGAAGGACCAAATCATGGTGGTCTTTTAACCCTGAAACCAATGCAATTCTTTGTGTTAATGCATTGGGTAGAAGTTATGTACTTCCTCTTGATGGCACTCCCACAGGTGTCACTCTTACTCTACTTTCAGGAAATCTATATGCTGAAGGTTTTAAAATGGCTGGTGGTCTTACCATCGAGCATTTACCTAAATACGTCATGATTGCTACACCTAGTAGAACCATCGTTTATACATTAGTTGGAAAACAATTAAAAGCAACTACTGCTACTGGATGGGCTTACTATGTAAAATCTAAAGCTGGTGATTACTCAACAGAAGCACGTACTGATAATTTGAGTGAACATGAAAAATTATTACATATGGTGTAA
Protein
MKYVLFIFACIIACVYGERYCAMKDDNPMSCINGTDSQCRTCFERGDLIWHLANWNFSWSVILIVFITVLQYGRPQFSWIVYGIKMLIMWLLWPIVLALTIFNAYSEYQVSRYVMFGFSVAGAVITFALWMMYFVRSIQLYRRTKSWWSFNPETNAILCVNALGRSYVLPLDGTPTGVTLTLLSGNLYAEGFKMAGGLTIEHLPKYVMIATPSRTIVYTLVGKQLKATTATGWAYYVKSKAGDYSTEARTDNLSEHEKLLHMV
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the alphacoronaviruses M protein family.
Uniprot
EMBL
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
263
Number of predicted TMHs:
4
Exp number of AAs in TMHs:
83.89171
Exp number, first 60 AAs:
27.38094
Total prob of N-in:
0.34563
POSSIBLE N-term signal
sequence
outside
1 - 3
TMhelix
4 - 23
inside
24 - 47
TMhelix
48 - 70
outside
71 - 79
TMhelix
80 - 102
inside
103 - 112
TMhelix
113 - 135
outside
136 - 263
