Strain
Avian_JQ065049
(Region: China: Hong Kong; Strain: Common-moorhen coronavirus HKU21 strain HKU21-8295, complete genome.; Date: 2007)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGGCTTCTGAGAGTTCTTATCAGCTTCGTGCTGTTCAAGAATTTGAAGAGTGGTCTCTTATAATATTTATATCTATAATATGGGCATTATCTTCCATTTTACAAGGGGGTTATGCAACACGTTATAGATTTGTTTATGTTATTAAACTAGTACTTTTGTGGCTTTTGCAGCCACTTACTTTAGGTTTTAGCATATATGCAGCTGTGTATTTTGCTATGCCTGCCACTTATTTGAAGTTAACTGGTGAGTCTACTGATTATATTAACCAGACTAACGCACATTATCAAAGGAATTATCATACATCTAAACTTTACTCTCGTAAAGGTCTCGATAATTCTGAAACTATTGCTCAATTTACTCTAGCTATTCTATTTGCTGTACTTACATTTGTATCATGGTGTAAGTATATGTATGATAGTATTAGACTAGCTCTCAAAACTAAATCTGCCTGGTCCTTTTCCCCAGAAACTAGGCTTATTGCTGGTATTGTAGACATGATGGGCAATGGGAGGTGTGTTCCCTTAGACTACATGACGCCAATATTAGCACCAGTCATTAAACACGGTACGCTTAAGCTACATGGGCAAAAGCTAGCATCTGGTTTGAGCGTTAAAACTGTACCTAAACATATGGCAGTATTCACTCCTAGTGATACTTTCCATTATGTCCTCCGTAAAACTATTGAGAGTACGGAAGACGATAATATTGCAGTGCTCATATATCAGAGTGATCGTGCATCGAATGCTGGGCTTCACACCATAACCACATCTGGTTCTGGTAATTCCAGATTATATAAGTATATGTAA
Protein
MASESSYQLRAVQEFEEWSLIIFISIIWALSSILQGGYATRYRFVYVIKLVLLWLLQPLTLGFSIYAAVYFAMPATYLKLTGESTDYINQTNAHYQRNYHTSKLYSRKGLDNSETIAQFTLAILFAVLTFVSWCKYMYDSIRLALKTKSAWSFSPETRLIAGIVDMMGNGRCVPLDYMTPILAPVIKHGTLKLHGQKLASGLSVKTVPKHMAVFTPSDTFHYVLRKTIESTEDDNIAVLIYQSDRASNAGLHTITTSGSGNSRLYKYM
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Uniprot
Pubmed
EMBL
Proteomes
Pfam
PF01635
Corona_M
Interpro
IPR002574
Corona_M
ProteinModelPortal
Ontologies
KEGG
GO
Subcellular Location
From MSLVP
Host nucleus > host nucleolus. Host cytoplasm. Secreted.
From Uniprot
Host Golgi apparatus membrane
Virion membrane
Virion membrane
Topology
Length:
268
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
64.2488000000002
Exp number, first 60 AAs:
31.48314
Total prob of N-in:
0.00775
POSSIBLE N-term signal
sequence
outside
1 - 14
TMhelix
15 - 37
inside
38 - 49
TMhelix
50 - 72
outside
73 - 114
TMhelix
115 - 134
inside
135 - 268
