Strain
Porcine_KT266822
(Region: China: Sichuan; Strain: Porcine deltacoronavirus strain CH/Sichuan/S27/2012, complete genome.; Date: 2012)
Gene
polyprotein 1a
Description
Annotated in NCBI,
polyprotein 1a
Location
GenBank Accession
Sequence
CDS
ATGGCCAAGAACAAGTCCAAGCGCGACGCTATCGCGTTGCCTGAAAATGTACCACCACCTCTGCAACTTTTCATCCACGTTGCAGCTGCTGAAGAGGGTCACCCTAAGGTTACTACTTACCTTGGCAACTATAACCTCTACGCTACCAAGGCTCCGCCTGGCGTGCAGGTTCTTAGTGCTAAAACCTCTCTTACTGATTTTGAGAATGTCTTTGGAGCTCAACCCACCTTGCGATCAATTCGTAATCTGGTGTGTGAGGCTCGCTCGGCTGAATGGACAACTTCCAAGAACGCTTTTGCACTCAAAGCCACTCAACTTGACTACTCTGATGCCGTTTTGAGGGCAATGATTCGTTTCTGCCCTCCAAAGGTGTCCACACTCGCTGCCTTTGCTCTTTTTGGCCGATTGGTTAAAATTGAGGACAAGGAACTTGCTGAGTTAGCTCGTGATACTGCCCTTGAGTTGGCGTACACTGCTAAAATTGGTACATCTCTTGCTGACACGAGATCTGTCTCACTTATTCATAAGGACGCCTATCTAACTCTCAGTAACGAGGTTGTTGGCGTAACTTTTACTGCTGCACTTATGGCAAAGGCTACCACTGTTAATGGAGCAATGCAATACTCAAACTTTTACCTCTACCCTCGCGCCACTATCAAGGTGACCGATGGTAAGGCTGAAGCAATTGCAACTAAGCCTCTGCCTGCTGCCACTAAAGGCAAGCCAATCACAGAGGATGTCAACCTCCTCCCTGACTATCAGCAGCTGCTTGTTGATCAAGTGACTGGCACTGAGGTTAAGGTTGGAGCCTTAACTTATGTTAAGACCACTGACCTACCACCCCTTTACTTTCCCAAAGTTAAAGGCGGTGTTGTTGGTATTGCACTTAAGCAGCAGGGCACTGCGGCTAAGAAGCTCAATGTAGTCTTTCATGCTCAACCTGATGATGTTCTGCTAGCTTTCATACAACTTCAGCAATTCTTGAACCGCACTTCGGATTCAAGTGTTGAAATTACTGATTGCCAGAGTTATGAAGTCTCTCCAACTGTGACGGTAAAAATTGGCCCGTCTAAACCTGGAGATGTCATCGTGGCTACTGATGAGGAATACCTTAAATGCTTTGAAACCCCCGAGGTAGGTAGGCTCTATAAGGTTTTCCAAACTCAATCTTGGGCTATCATTGAGCGTTCCTTCTCCAGGATCCGCGTGTCCAAAGCTTTATCAGCATTTATAAGTTTTCTGCAAAACCTTGCAGATAACTTTACTGCACTAAGTGGTGTTGTCACTGCACTCATTCGTGAACTCCAGGATCTCACCCTGGATGTGGCGACACGTATCACTAACATACAATTTGTTTACCGCGCTGGTAAGCTTATTGTCGACACGACAAGTGTCATAGCTAAACTTTTCCAGCCATTTTGTGATTTTATATCACCTTTCCTTCGGAAAGTGGCTGGTTTTGCAATTTACACTGTTGGTAATCGCATGCTTATGTTTACCAGCACTGGCACCTTTCTTCTCACAAAGGCAACTACTAAGATACTCAATAAGGCAAAGTACATCTTTGATGTTGAGCCTGAGTATCCAGTAGCTGTAACAACATCTAAAGTTGTAGTACATGAAGCACTCCAGCAAATCGACACTAAGCCTGCTAGAGCTCTAGAGGCTGTTGATGTCGTTGTTGGTAACACTGTACTGCAAATGGCTACTGATGGCACTGCGTTCTACCCATCAGATGGTACGCATGCCTCTTTACCAGGATTCAAAGCAGGTTCGGATGAGCTTCTCATAAGCTTCAACTGCGACCTCTTTGATGATGAGACTAATGCTCAAATCAACGAAACACTCGCTGCATATGAGCTTAACCAACTAGTAGCTCCAGGTGATTCTACACCGCGTCAAATTGCGACGTTGGTTGTCGATACACTTGTGGATGCTATAACGGACCACTTTCCGGAGAAAACCATTGATCTACCTGAAGACTATCAAGTCTTTTCTGACCATGATGACCTCCTACTTGCACAATACCACATCCCTGATCACCTGAGCCTGTATATTCAAGCTATGGAGGGTGAGGATGATAGTGGTGATGAAATATGTATTGAGGACGATGATTACGACTGTCCTCAAGCCGACGAAAACACAGAAGGAGTAATTCCCCAACAGTGGGAACTTCCTGATGTTGATAAATTTTTACTCACGATCCAGGAACGGAAGACCAGCAGCGACGAAGTACTTAGCGTTGACGTCTATCCTAAACCAGATGAGGTTGGGGTTGACGACAGCGCGTCGGAAAAGAAGCCAAATGGGGACCCAGTACCGGATCCTGAGGTTCATCCAACACTAGAGAGTGTGGATGTTGAACAACCAACTGAAACAGCAAACCAGGCTGTTAAAGACAAACCTTCTGATACCACCTTTGTGGTTGATGAGGAACAATTACAAGAATCAACACCAGAACCTGAGCTCCGCTCCTATGAAGGGGAGTTTGATTCTGATGATGAAATTATTATCCCTATAGTACCAGTAACACCTGCGGATTTAAAACCACAGACTATTACTATAAAGGAGTACTTTAAGTCTGAAAAACTTGAGACTATTAACGAAGGATCTACAGAGTCGGTTGCACAGTCTGACGATTCGTTCGACGAATCATTTGCTGATGCTGAGTCTGATGATCCACAAGACCCTGCTGTATATGATGATACAACAATTATAACGGATAGTACTGATGTAGGCGATGAGCCTGAGACAACTCTAGCTACCATCGTTAACACACCTCTGACACTCGATAATAACTTGCCACCTGAAGCCATTAAACAACCCAGACCGACTAAGGTTGAGTTAGTTGTTGGTGAATTGGCGAGTATTAAATTTGACAATTCTGTCCTAGTCAACCCTGCTAATGCGCAATTAACAAATGGCGGTGGAGCTGCCCGTGCAATTGCAAAATTAGCTGGTCCAAAATATCAAGAGTACTGTAATAGTGTGGCTCCTATCTCAGGACCGCTTACCACGGACTCTTTTGATGCCAAGAAACTTGGTGTAGCCTGCATCTTGCATGTAGTGCCACCCAAAGGTTCTGACCCTAATGTACAAGAACTCCTGTATCAAGCTTACAAGAGTATCCTTACTGAACCAGCACATTATGTTATACCTATACTAGGTGCTGGTATCTTTGGATGCAACCCAGTCCACTCTCTGGATGCGTTCAGGAAAGCATGTCCAAGTGACATAGGTCGTGTCACCCTTGTCACTATGAACAAAAACCATTTGCAGGTGTGGGATGCTCTCAATAGGACCATTGTACGCACCACTACTGACTATGATCAAGTTACCACCAAGGCCCTTACACCCCAGGGAGTGTTAGAAGCCAATCTCTTTGATGGTGAGGACTTTGTTCAAGAACCAAAACCCGGTCAAATCTACCTTGAGGTTACTGAAGAAGTTCAGAACCAAGCCAAGGAACTTGACCTTAACCTTCAGCAATACTGCGTCTACCTGAAGACTTGCCACCATAAATGGGTTGTGAGTCGTACGAACGGGTTGATGCATCTAAAACAAAAAGATAACAATTGTTTTGTTAGTGCAGGTGTAAACCTGTTTCAAAACACTGCTTATCAACTTAGACCTGCTATTGATGCTCTCTATAGGGAGTATCTCAATGGTAATCCAAACAGATTTGTTGCTTGGATCTACGCATCCACTAACCGTCGTGTTGGTGAGATGGGTTGTCCACAGCAAGTTATTTCTTTGCTCGTTAGTAACTCTGACGCAGCATTTTCAGCAACTACAGCCTGTTGTAACACCTACTTTAACCACACAGGTGTTATTTCAGTAGCTCGTGAATATGACCCAATACAACCAAAGGTCTACTGCATGAAGTGTGATGTGTGGACTCCCTTTACACCCCAGAGTGGAAAAGGTGCAGTTGCAATTGGTACTTCTGCAGATGAACCTACCGGTCCTGCCATTAAATTTGCCGCAGCTCACTGCTGGTACACTAATGGCAAGAAAACAGTTAATGGCTATGACACTAAAGCTAATGTTGTAGCTACCTATCATAGGTTTGACGTGCCTAAGCCTCAACTTGTCGAGGACGTGGTTGCGCTGCCTACTAAAAATGACTTTGAAGTTCTCAATGTTGAAGAACTGCCACAGGATAGTGTGCTCCATTTGGACCCACCTCCTGTACAGGCCTTACAACCTAAGGCTAACCAACACATTGAGATTCTAGAAAACCCAGATTATCTGGACATTTTGGATCTTTGGATTCGTAAACCCAAATTCATCCTCGTAAAGTCGTGGAGTGTTTTGGGTAGAGCACTATGTAAGGCAGGTAAAGTTGTCTTTGTCAGTGCTTCGCTTTTGACCCGTTTCTACAATTACCTTGTAGAGATTGGTGCTCTTGACTCAACAATAAGGTTGTCAGTCGATCTTACCTGTAAATTTGTTAGAACGGTACTCCCATCGTCTAACACTGTACACAAAACTTGTCTTGGTCTGTATTATTCAGCCCAGACACTTTTTGTTTCTTTAGCACCATTCCTTATGTTACCAGCTGTAGTTAGTCTGCTTAATTCAGGCTATACAATTGGCACATATTTGTATGCAAAAACTGGCTGGCCTTGTAATTACAATGCCACGCAACACTTTGATTATAATTCTTACTGTGCAGGTGACTTGGTTTGTCAAGCCTGTTTTGACGGTCAAGACTCCCTACATTTGTATCCGCATTTACGTGTTAATCAGCAGCCCCTTCAGACCACTGACTACACTGTTTATGCGCTTTCACTAATACTACTATTAGCTAACATGACTCTTGTCATGGGCACGCTAATAGTTACTTTCTTTGTGAACTTCTATGGTGTGCAAATACCATTTTATGGTACACTTTTGATAGATTATCAGTCCGCGCTGATGATGACTTTCTCAGTGTACTACTTTTATAAGGTAATGAAGTTTTTCCGCCATCTCACACATGGATGTAAAATTCCAACGTGTATGGTATGTGCTAAACTTCGTACCCCACCTACTATAACAGTTGAGACTGTCGTTCAAGGCAGGAAATACCCATCTGTTATTGAAACAAATGGCGGGTTTACAATTTGTAAAGAACACAACTTCTATTGCAAAGACTGCTCTCTACAAACACCCGGCACTTTCATCCCGACAGAAGCTATTGAGTCGCTCTCACGAGCCACCAGGCTTAGTGTCAAACCAACAGCACCAGCATTCTTACTTGCTAGAGATGTTGAGTGCCAAACTGATGTTGTCGTTGCTCGCGCAATGCATAACCAAAATGCGCATGTGTGCATTTCAAAATACTCTGATATCCGTACCGTTGACCAACTACTTAAGCCTACTCCACTGTTTTCATACACTCCCGATGTTATCATCGCGGCAGACTTTGACAACAGAGGTAGTCTTAAGACAGCTAAAGAATTAGCTGTGGTTTTGTCAATGGACCTTAAACGTACTATAATTATCATTGATCAGGCCTATTCTAGACCCATTGATAATTATCAGGAAGTTGCTTCTCGTATTGAGAAGTATTACCCAGTTGCAAAGATCACACCCACAGGTGACATCTTTACAGACATTAAGCAAGCGACCAATGGCCAAGCTAGTGACTCTGCTATTAATGCAGCTGTTCTGGCTGTCCAGCGCGGTCTTGATTTTACAATTGACAACCCTAACAATATACTACCACATTACGCCTTTGACTTTTCAACCCTCAATGCAGAAGACCAGTCTACCATTTTGGAGAGTGGTTGTGCTAAAGGCAATCTCAAGGGCACTAATGTTGGTGTTGTTCTTTCAGCTAGCCTTGTTACACGTCTTAGTCAGCAGGCTATACGTGTGATTGCTAATGCTGCTTCACGTAATGGTGTTACATGCGCCGTTACTCCATCTACACTTGTTATGCGTGGGAATATTGCAACACAGCCCTTGACTCGCATCAAAGCTGGTGCACCTCCCATGCGTCAAAAAATTTTATGTGTTATCCTGGCACTTGCTATTGTGTACTTTGCTGCTATGGCTTTCGGCTTTTTGGCAAGTCAAATTACGCTTAATACAGTGCCTACGATTAAATCTGATATCCGCGCCTCCACCTTCTACGTTGTTAGAGATGGAGTCTTGGATACTGTTCGTTCAAATGACAAGTGCTTTGCAAATAAGTTTTTGGCATTTGATAGCTTCATTCAAGCACCTTACACTAATTCACCTGACTGTCCAGTTGTTGTGGGAGTTGTTGAAGTAACGACGCACTCTATTCCTGGAATTCCAGCAGGTGTCATTCATAGAGACGGTCTCATACTTAACATTTATGAACAGTCTCTTTATGAAACCCATCAGCGTCAGTCTATGGTTAGGGATGCGTTGTCACTCAAGACAGCAAATCTCTTTAACCTAGGCAAGCGTGTTGTAGTAGGATACACTCAACATGAAGTTGTTGTGGGTACCTCCTATTTTAATTCTCCTGCACTTTTTAACGCAAAGTGCACCTTCTTACAGTATCAGGACACTAGACAACTCTATTGCTATGATACTGTTCCTACTGAACATAAGCTTTACTCTGATGTGCTTCCGCACGTCGAGTATAAGGCTATTGACATTAATGGTGATCTTGTTCCTTTCAAGATACCAGAGCAGATAATGTTCTATCCACATATTGTGCGCTATACTAGCAATTCCTATTGCCGTATGGGGCATTGTTTTAATACTAACCCTGGTATTTGCATTTCATTTACGGACGAATTTCCGTATAGTGAAAATGTTAAACCTGGTGTGTACTGTGCTGATACCTCTTTGCAGTTGTTTTCAAACCTCGTTTTGGGCACTGTATCTGGTATTCACATCTTTACATCAACAGCTGCATTGCTTGGATCTACTATTGTGATCATACTATGCGTTGTTGCTGTTCTTGCAGTTCAGCGATTCTTCAAGGAGTACACAACTTTTGTTATGTACACTTGTGGTCTTGCTCTTGTCAACATTGTGGGCATTGCACTTATGTACAAGTGCCTTGTCTTCGCGATTTTTTATTATGCAATCTACCTTTACTTTGTCCTTACTTTCCCCTCCTTTAAGAGGAATGTGGCATTGTTTTACTTCGCTGTAGTGATCGTGCCGCACGTGAGTAACATGCAATTGCTTGCGCTCATTGTGTGTAGCATTATCTACTTTCTCTACACCTATGTTCATACTGTAGCTAAGACAGCTGGGAAATTTTCTTCCTTCTTAGACGCAGCTAAAGCTACTTTTGTCATTGACAATGAAAAGTACGTGTTGCTTAAAGACCTCGCTGGTGCTGAATTTGACCAGTATCTGGCCTCTTACAACAAGTACAAATACTTTTCTGGTACTGCTTCTGATAAGGATTATGATAAGGTCTGTATGGCATTTCTTGCCAAGGCTTTGTCATCTTTTCGTGAAGGAGGCGGTTCACAGTTGTACACACCACCTAAATTTGCAGTTGTTCAGAGTCTTAAGACCAAGCTGCAAGCAGGTATCAAAATCCTCCTGCACCCTTCAGGTGTAGTTGAGCGATGTATGGTCTCAGTTGTCTACAATGGATCTGCATTGAATGGCATCTGGCTTAAGAATGTTGTCTACTGCCCACGCCATGTAATTGGAAAATTCCGTGGTGACCAGTGGACTCACATGGTCTCAATTGCTGATTGCCGCGACTTTATAGTCAAGTGTCCAATACAGGGTATTCAGCTAAATGTCCAATCAGTTAAGATGGTAGGAGCTCTCCTCCAGTTAACTGTTCATACCAACAACACAGCCACTCCAGACTATAAGTTTGAAAGGCTCCAACCAGGATCATCGATGACAATTGCTTGTGCTTATGATGGCATTGTACGGCATGTCTATCACGTGGTCCTCCAACTTAATAATCTTATTTATGCAAGCTTCCTTAACGGAGCTTGTGGTAGTGTGGGTTACACTCTTAAGGGTAAAACACTCTACTTACATTACATGCACCACATTGAGTTTAACAACAAAACTCATAGTGGTACAGATCTTGAAGGTAACTTCTATGGCCCCTATGTGGATGAGGAAGTTATTCAGCAGCAAACAGCATTCCAGTATTACACTGATAATGTTGTTGCTCAATTATATGCACACTTACTGACTGTTGATGCTAGACCAAAATGGCTGGCACAATCTCAGATAAGTATCGAGGATTTCAACTCATGGGCTGCTAACAATTCCTTTGCTAACTTCCCATGTGAACAAACTAATATGTCCTACATTATGGGACTCTCGCAAACTGCTCGAGTCCCTGTAGAACGTATCCTCAATACCATTATACAGCTAACCACCAATAGAGATGGTGCTTGTATTATGGGATCTTATGATTTCGAGTGCGATTGGACGCCAGAGATGGTATACAATCAGGCTCCAATTTCATTGCAGTCAGGAGTAGTTAAGAAAACTTGTACGTGGTTCTTCCACTTCTTGTTTATGGCTATTACCATGCTACTCGCTGCCATGCATGTTTTCCCTGTACACTTGTACCCAATAGTACTGCCATGCTTCACTGTTGTGGCATTCCTGTTGACTTTAACCATTAAACACACTGTTGTGTTTACCACTACATATTTGCTTCCGTCACTTTTGATGATGGTTGTAAATGCTAACACTTTTTGGATACCGAACACATTTCTGCGCACCTGCTACGAAACTATATTCGGTTCCCCAATTGCTCAGCGACTGTATGGTTACACTGTTGCTCTTTATATGCTGATCTATGCTGGACTTGCAATCAACTATACGTTGAAAACACTCCGGTATAGAGCAACTTCATTCTTATCTTTTTGCATGCAGTGGTTTCAATATGGTTATGTTGCACACATTGCGTACAAACTGCTTAATAAACCCTGGACAGAATCACTACTCTTCACAGCCTTCACAATGCTAACCAGTCATCCTTTGTTGGCTGCTCTTAGCTGGTGGCTAGCTGGTCGCGTAACTCTGCCCATTATCATGCCTGACTTAGCTATTCGTGTTTTGGCGTATAACGTCATTGGCTATGTCATATGTGTTCGATTTGGCCTTATGTGGCTTGCAAATCGGTTCACAACTGTACCTATGGGCACATACCAGTATATGGTGTCTGTAGAGCAACTTAAGTACATGATGGCAGTTAAGATGTCCCCACCGCGTAATGCGTTTGAGGTGCTTATAGCCAACATTAGACTTCTTGGTTTGGGTGGAAACCGTAACATTGCTGTTTCTACTGTCCAAAACAAAATTCTTGATGCAAAAGCTACTGCTGTTGTTGTTGCTAACCTTCTTGAAAAGGCTGGCGTCACAAACAAGCACGCTATTTGCAAAAAGATTGTGAAACTCCACAATGATACCCTTAAAGCCACCACTTATGAGGAGGTTGAGGTAGCACTTGTGAAACTTCTTTCTCACATAATTGAGTTCTTGCCAACTGATCAGGTAGATGCTTATCTAGCTGATGCGGCCAATGCTCAACATGTTAATACCTATTTCGACAACTTGCTTGAGAACAAAGCTGTTGTTCAGGCTGTTGCCGATATCAACATTAATCTGGATTCTTATAGAATTTATAAGGAGGCAGATGCTATTTACAAACGATCTGTTGAGATGAACGAATCTCTACAGGAGCAAAAGAAAAAGCTTAAAGCTGTTAACATTGCAAAGGCGGAATGGGAGCGTGAGGCTGCTTCTCAGCGTAAGCTTGAAAAGCTTGCTGATGCTGCTATGAAGTCTATGTATCTTGCAGAACGTGCTGAGGATCGTCGCATTAAGCTAACCTCTGGACTTACTGCAATGCTTTACCATATGCTTAGACGTCTTGACTCAGATAGGGTAAAAGCTCTGTTTGAGTGCGCTAAGGCACAAATCTTGCCAATACATGCTGTAGTTGGAATTTCTAATGACAACCTTAAAGTTATTTTTAACGATAAGGATAGCTACTCTCATTATGTAGAGGGCAACACACTTATACATAAGGGAGTTCGCTACACTATTGTGAAGAAACTCTCCTTAGATAATGCACCTATTGAAGGCGTACCAGAAGAATTCCCTGTGGTCGTTGAGACTGTTAGGGAAGGTGTGCCCCAGTTGCAAAACAATGAGCTATGTTTGCGCAATGTTTTCACTGCTCAGAACACAGCTCAGGACTTCAATGGCAATGAATCCACTGTAAAATCTTTTTATGTTACTAGAACCGGTAAGAAGATTTTGGTTGCCATTACATCAACTAAAGACAATCTTAAGACTGTGACCTGCCTTACTGAGACCGGTAAGACAGTCCTTAACTTGGACCCTCCTATGCGCTTCGCACATACCGTAGGTGGAAAACAGTCTGTTGTCTATCTCTATTTTATTCAGAATATTAGTTCACTCAACAGAGGTATGGTTATTGGCCACATCTCTGAAACTACTATCCTTCAGGCAAGTGGTACTCAAATTGAGTACCAGCAAAATGCCTCTCTTCTGACCTATTTGGCTTTCGCTGTAGACCCTAAGACAGCCTACCTTAAGCATCTTGCTGATGGTGGGTCTCCTATACAGGGTTGTATTCAGATGATTGCTACTATGGGTCCTGGATTTGCAGTTACTACTAAACCACAACCTAATGAGCATCAGTATTCTTATGGTGGTGCTTCAATTTGTCTTTATTGCCGTGCTCATATACCACATCCTGGTGTTGATGGACGGTGCCCCTACAAAGGCCGCTTTGTTCACATCGACAAAGATAAGGAACCTGTTTCCTTCGCCTTGACTCATGAGCCATGCAGTTCTTGTCAACGGTGGGTCAATTATGACTGCACCTGTGGATCTAGTCTGCAGAATTCGGCTTATTTAAACGAGTAA
Protein
MAKNKSKRDAIALPENVPPPLQLFIHVAAAEEGHPKVTTYLGNYNLYATKAPPGVQVLSAKTSLTDFENVFGAQPTLRSIRNLVCEARSAEWTTSKNAFALKATQLDYSDAVLRAMIRFCPPKVSTLAAFALFGRLVKIEDKELAELARDTALELAYTAKIGTSLADTRSVSLIHKDAYLTLSNEVVGVTFTAALMAKATTVNGAMQYSNFYLYPRATIKVTDGKAEAIATKPLPAATKGKPITEDVNLLPDYQQLLVDQVTGTEVKVGALTYVKTTDLPPLYFPKVKGGVVGIALKQQGTAAKKLNVVFHAQPDDVLLAFIQLQQFLNRTSDSSVEITDCQSYEVSPTVTVKIGPSKPGDVIVATDEEYLKCFETPEVGRLYKVFQTQSWAIIERSFSRIRVSKALSAFISFLQNLADNFTALSGVVTALIRELQDLTLDVATRITNIQFVYRAGKLIVDTTSVIAKLFQPFCDFISPFLRKVAGFAIYTVGNRMLMFTSTGTFLLTKATTKILNKAKYIFDVEPEYPVAVTTSKVVVHEALQQIDTKPARALEAVDVVVGNTVLQMATDGTAFYPSDGTHASLPGFKAGSDELLISFNCDLFDDETNAQINETLAAYELNQLVAPGDSTPRQIATLVVDTLVDAITDHFPEKTIDLPEDYQVFSDHDDLLLAQYHIPDHLSLYIQAMEGEDDSGDEICIEDDDYDCPQADENTEGVIPQQWELPDVDKFLLTIQERKTSSDEVLSVDVYPKPDEVGVDDSASEKKPNGDPVPDPEVHPTLESVDVEQPTETANQAVKDKPSDTTFVVDEEQLQESTPEPELRSYEGEFDSDDEIIIPIVPVTPADLKPQTITIKEYFKSEKLETINEGSTESVAQSDDSFDESFADAESDDPQDPAVYDDTTIITDSTDVGDEPETTLATIVNTPLTLDNNLPPEAIKQPRPTKVELVVGELASIKFDNSVLVNPANAQLTNGGGAARAIAKLAGPKYQEYCNSVAPISGPLTTDSFDAKKLGVACILHVVPPKGSDPNVQELLYQAYKSILTEPAHYVIPILGAGIFGCNPVHSLDAFRKACPSDIGRVTLVTMNKNHLQVWDALNRTIVRTTTDYDQVTTKALTPQGVLEANLFDGEDFVQEPKPGQIYLEVTEEVQNQAKELDLNLQQYCVYLKTCHHKWVVSRTNGLMHLKQKDNNCFVSAGVNLFQNTAYQLRPAIDALYREYLNGNPNRFVAWIYASTNRRVGEMGCPQQVISLLVSNSDAAFSATTACCNTYFNHTGVISVAREYDPIQPKVYCMKCDVWTPFTPQSGKGAVAIGTSADEPTGPAIKFAAAHCWYTNGKKTVNGYDTKANVVATYHRFDVPKPQLVEDVVALPTKNDFEVLNVEELPQDSVLHLDPPPVQALQPKANQHIEILENPDYLDILDLWIRKPKFILVKSWSVLGRALCKAGKVVFVSASLLTRFYNYLVEIGALDSTIRLSVDLTCKFVRTVLPSSNTVHKTCLGLYYSAQTLFVSLAPFLMLPAVVSLLNSGYTIGTYLYAKTGWPCNYNATQHFDYNSYCAGDLVCQACFDGQDSLHLYPHLRVNQQPLQTTDYTVYALSLILLLANMTLVMGTLIVTFFVNFYGVQIPFYGTLLIDYQSALMMTFSVYYFYKVMKFFRHLTHGCKIPTCMVCAKLRTPPTITVETVVQGRKYPSVIETNGGFTICKEHNFYCKDCSLQTPGTFIPTEAIESLSRATRLSVKPTAPAFLLARDVECQTDVVVARAMHNQNAHVCISKYSDIRTVDQLLKPTPLFSYTPDVIIAADFDNRGSLKTAKELAVVLSMDLKRTIIIIDQAYSRPIDNYQEVASRIEKYYPVAKITPTGDIFTDIKQATNGQASDSAINAAVLAVQRGLDFTIDNPNNILPHYAFDFSTLNAEDQSTILESGCAKGNLKGTNVGVVLSASLVTRLSQQAIRVIANAASRNGVTCAVTPSTLVMRGNIATQPLTRIKAGAPPMRQKILCVILALAIVYFAAMAFGFLASQITLNTVPTIKSDIRASTFYVVRDGVLDTVRSNDKCFANKFLAFDSFIQAPYTNSPDCPVVVGVVEVTTHSIPGIPAGVIHRDGLILNIYEQSLYETHQRQSMVRDALSLKTANLFNLGKRVVVGYTQHEVVVGTSYFNSPALFNAKCTFLQYQDTRQLYCYDTVPTEHKLYSDVLPHVEYKAIDINGDLVPFKIPEQIMFYPHIVRYTSNSYCRMGHCFNTNPGICISFTDEFPYSENVKPGVYCADTSLQLFSNLVLGTVSGIHIFTSTAALLGSTIVIILCVVAVLAVQRFFKEYTTFVMYTCGLALVNIVGIALMYKCLVFAIFYYAIYLYFVLTFPSFKRNVALFYFAVVIVPHVSNMQLLALIVCSIIYFLYTYVHTVAKTAGKFSSFLDAAKATFVIDNEKYVLLKDLAGAEFDQYLASYNKYKYFSGTASDKDYDKVCMAFLAKALSSFREGGGSQLYTPPKFAVVQSLKTKLQAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGDQWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPDYKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGYTLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYYTDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTNMSYIMGLSQTARVPVERILNTIIQLTTNRDGACIMGSYDFECDWTPEMVYNQAPISLQSGVVKKTCTWFFHFLFMAITMLLAAMHVFPVHLYPIVLPCFTVVAFLLTLTIKHTVVFTTTYLLPSLLMMVVNANTFWIPNTFLRTCYETIFGSPIAQRLYGYTVALYMLIYAGLAINYTLKTLRYRATSFLSFCMQWFQYGYVAHIAYKLLNKPWTESLLFTAFTMLTSHPLLAALSWWLAGRVTLPIIMPDLAIRVLAYNVIGYVICVRFGLMWLANRFTTVPMGTYQYMVSVEQLKYMMAVKMSPPRNAFEVLIANIRLLGLGGNRNIAVSTVQNKILDAKATAVVVANLLEKAGVTNKHAICKKIVKLHNDTLKATTYEEVEVALVKLLSHIIEFLPTDQVDAYLADAANAQHVNTYFDNLLENKAVVQAVADININLDSYRIYKEADAIYKRSVEMNESLQEQKKKLKAVNIAKAEWEREAASQRKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRLDSDRVKALFECAKAQILPIHAVVGISNDNLKVIFNDKDSYSHYVEGNTLIHKGVRYTIVKKLSLDNAPIEGVPEEFPVVVETVREGVPQLQNNELCLRNVFTAQNTAQDFNGNESTVKSFYVTRTGKKILVAITSTKDNLKTVTCLTETGKTVLNLDPPMRFAHTVGGKQSVVYLYFIQNISSLNRGMVIGHISETTILQASGTQIEYQQNASLLTYLAFAVDPKTAYLKHLADGGSPIQGCIQMIATMGPGFAVTTKPQPNEHQYSYGGASICLYCRAHIPHPGVDGRCPYKGRFVHIDKDKEPVSFALTHEPCSSCQRWVNYDCTCGSSLQNSAYLNE
Summary
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
Similarity
Belongs to the coronaviruses polyprotein 1ab family.
Uniprot
Pubmed
EMBL
Proteomes
Pfam
Interpro
IPR032505
Corona_NSP4_C
IPR009469 RNA_pol_N_coronovir
IPR008740 Peptidase_C30
IPR027352 CV_ZBD
IPR001205 RNA-dir_pol_C
IPR036333 NSP10_sf
IPR037227 EndoU-like
IPR014822 NSP9
IPR009003 Peptidase_S1_PA
IPR027417 P-loop_NTPase
IPR037230 NSP8_sf
IPR038123 NSP4_C_sf
IPR029063 SAM-dependent_MTases
IPR018995 RNA_synth_NSP10_coronavirus
IPR009466 NSP11
IPR014829 NSP8
IPR014827 Viral_protease
IPR042515 Nsp15_N
IPR009461 Coronavirus_NSP16
IPR002589 Macro_dom
IPR027351 (+)RNA_virus_helicase_core_dom
IPR007094 RNA-dir_pol_PSvirus
IPR036499 NSP9_sf
IPR009469 RNA_pol_N_coronovir
IPR008740 Peptidase_C30
IPR027352 CV_ZBD
IPR001205 RNA-dir_pol_C
IPR036333 NSP10_sf
IPR037227 EndoU-like
IPR014822 NSP9
IPR009003 Peptidase_S1_PA
IPR027417 P-loop_NTPase
IPR037230 NSP8_sf
IPR038123 NSP4_C_sf
IPR029063 SAM-dependent_MTases
IPR018995 RNA_synth_NSP10_coronavirus
IPR009466 NSP11
IPR014829 NSP8
IPR014827 Viral_protease
IPR042515 Nsp15_N
IPR009461 Coronavirus_NSP16
IPR002589 Macro_dom
IPR027351 (+)RNA_virus_helicase_core_dom
IPR007094 RNA-dir_pol_PSvirus
IPR036499 NSP9_sf
SUPFAM
Gene 3D
ProteinModelPortal
PDB
2Q6F
E-value=3e-71 Score= 242 Identity=44.44%
Cov(Q)=8.45% Cov(P)=99.03%
3D Structure
Ontologies
GO
GO:0039694 P:viral RNA genome replication
GO:0033644 C:host cell membrane
GO:0044165 C:host cell endoplasmic reticulum
GO:0005524 F:ATP binding
GO:0019082 P:viral protein processing
GO:0008270 F:zinc ion binding
GO:0016896 F:exoribonuclease activity, producing 5'-phosphomonoesters
GO:0016021 C:integral component of membrane
GO:0004197 F:cysteine-type endopeptidase activity
GO:0003724 F:RNA helicase activity
GO:0039520 P:induction by virus of host autophagy
GO:0008168 F:methyltransferase activity
GO:0003968 F:RNA-directed 5'-3' RNA polymerase activity
GO:0032259 P:methylation
GO:0006351 P:transcription, DNA-templated
GO:0003723 F:RNA binding
GO:0044220 C:host cell perinuclear region of cytoplasm
GO:0008242 F:omega peptidase activity
GO:0033644 C:host cell membrane
GO:0044165 C:host cell endoplasmic reticulum
GO:0005524 F:ATP binding
GO:0019082 P:viral protein processing
GO:0008270 F:zinc ion binding
GO:0016896 F:exoribonuclease activity, producing 5'-phosphomonoesters
GO:0016021 C:integral component of membrane
GO:0004197 F:cysteine-type endopeptidase activity
GO:0003724 F:RNA helicase activity
GO:0039520 P:induction by virus of host autophagy
GO:0008168 F:methyltransferase activity
GO:0003968 F:RNA-directed 5'-3' RNA polymerase activity
GO:0032259 P:methylation
GO:0006351 P:transcription, DNA-templated
GO:0003723 F:RNA binding
GO:0044220 C:host cell perinuclear region of cytoplasm
GO:0008242 F:omega peptidase activity
Subcellular Location
From MSLVP
Capsid
From Uniprot
Host cytoplasm
Host perinuclear region
Host endoplasmic reticulum
Host membrane
Host perinuclear region
Host endoplasmic reticulum
Host membrane
Topology
Length:
3621
Number of predicted TMHs:
14
Exp number of AAs in TMHs:
326.204739999999
Exp number, first 60 AAs:
0.00506
Total prob of N-in:
0.07263
outside
1 - 1507
TMhelix
1508 - 1530
inside
1531 - 1595
TMhelix
1596 - 1618
outside
1619 - 1627
TMhelix
1628 - 1650
inside
1651 - 1998
TMhelix
1999 - 2021
outside
2022 - 2287
TMhelix
2288 - 2310
inside
2311 - 2330
TMhelix
2331 - 2353
outside
2354 - 2367
TMhelix
2368 - 2399
inside
2400 - 2819
TMhelix
2820 - 2839
outside
2840 - 2842
TMhelix
2843 - 2860
inside
2861 - 2866
TMhelix
2867 - 2889
outside
2890 - 2908
TMhelix
2909 - 2931
inside
2932 - 2937
TMhelix
2938 - 2955
outside
2956 - 2969
TMhelix
2970 - 2992
inside
2993 - 3003
TMhelix
3004 - 3026
outside
3027 - 3621
