Strain
Feline_KU215421
(Region: Belgium; Strain: Feline coronavirus isolate Cat2_day21_deletion, complete genome.; Date: 2013)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGAAGTACGTTTTGCTCATGTTCGCGTGCATAATTGCATGCGTTTGTGGTGAACGATACTGTGCCATGCAAGGTGCAAGTACAAGCTGCATCAATGGCACCAACTCAGAATGTCAAACCTGCTTTGAACGTGGTGATCTTATTTGGCATCTTGCTAACTGGAACTTCAGCTGGTCCGTAATATTGATCGTTTTTATAACAGTTTTACAATATGGAAGACCGCAATTTAGCTGGCTCGTTTATGGCATTAAAATGCTGATCATGTGGCTATTATGGCCTATTGTTCTAGCGCTTACGATTTTTAATGCATACTCCGAGTACCAAGTTTCCAGATATGTAATGTTCGGCTTTAGTGTTGCAGGTGCAGTCATAACGTTTGCACTCTGGATGATGTATTTTGTGAGATCCATTCAGCTATATAGAAGGACCAAATCATGGTGGTCTTTCAACCCTGAAACTAATGCAATTCTTTGTGTTAACGCACTGGGTAGAAGTTATGTTTTACCCCTTGATGGCACTCCTACAGGTGTCACTCTTACTTTGCTTTCAGGAAATCTATATGCTGAAGGTTTTAAGATGGCTGGTGGTCTTACCATCGAGCAATTGCCTAAATACGTCATGATTGCTACACCTAGTAGAACCATCGTTTACACATTAGTTGGGAAACAATTAAAAGCAACTACTGCTACAGGATGGGCTTACTATGTAAAATCTAAAGCTGGTGATTACTCAACAGAAGCACGTACTGATAATTTGAGTGAACATGAAAGATTATTACATATGGTGTAA
Protein
MKYVLLMFACIIACVCGERYCAMQGASTSCINGTNSECQTCFERGDLIWHLANWNFSWSVILIVFITVLQYGRPQFSWLVYGIKMLIMWLLWPIVLALTIFNAYSEYQVSRYVMFGFSVAGAVITFALWMMYFVRSIQLYRRTKSWWSFNPETNAILCVNALGRSYVLPLDGTPTGVTLTLLSGNLYAEGFKMAGGLTIEQLPKYVMIATPSRTIVYTLVGKQLKATTATGWAYYVKSKAGDYSTEARTDNLSEHERLLHMV
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the alphacoronaviruses M protein family.
Uniprot
EMBL
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
262
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
74.7696199999999
Exp number, first 60 AAs:
18.93188
Total prob of N-in:
0.50879
POSSIBLE N-term signal
sequence
inside
1 - 48
TMhelix
49 - 71
outside
72 - 85
TMhelix
86 - 105
inside
106 - 111
TMhelix
112 - 134
outside
135 - 262
