Strain
Avian_KX375808
(Region: China; Strain: Infectious bronchitis virus strain ck/CH/LHLJ/99I, complete genome.; Date: 1999)
Gene
M protein
Description
Annotated in NCBI,
M protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGTCGAACGGCACGGAAAATTGCACTCTTAGTACTCAGCAAGCAGCTGAGCTCTTCAAGGAATATAATTTATTCATAACCGCATTCCTATTGTTTCTAACCATACTACTTCAGTATGGATACGCAACTAGGAGTCGGTTTATTTACATACTGAAAATGATAGTGTTATGGTGCTTCTGGCCCCTTAACATAGCAGTAGGTATAATTTCATGTATATATCCGCCAAACACAGGAGGTCTTGTCGCAGCGATAATACTTACTGTGTTTGCGTGTCTTTCTTTTGTAGGTTATTGGATCCAGAGTTTTAGACTCTTTAAGCGGTGCAGATCTTGGTGGGCATTTAACCCAGAATCGAATGCCGTAGGTTCAATACTCCTAACTAATGGTCAACAATGTAATTTTGCTATAGAGAGTGTGCCAATGGTGCTTTCTCCAATTATAAAGAATGGTGCTCTTTATTGTGAGGGTCAGTGGCTTACTAAGTGTGAACCAGACCACTTGCCTAAAGATATATTTGTTTGTACTCCAGATAGAAGAAATATCTACCGTATGGTGCAGAAATACAGTGGTGACCAAAGCGGAAATAAGAAAAGGTTTGCTACATTTGTCTATGCAAAACAGTCAGTAGACACTGGCGAGCTTGAAAGTGTAGCAACAGGAGGAAGTAATCTTTACACATAA
Protein
MSNGTENCTLSTQQAAELFKEYNLFITAFLLFLTILLQYGYATRSRFIYILKMIVLWCFWPLNIAVGIISCIYPPNTGGLVAAIILTVFACLSFVGYWIQSFRLFKRCRSWWAFNPESNAVGSILLTNGQQCNFAIESVPMVLSPIIKNGALYCEGQWLTKCEPDHLPKDIFVCTPDRRNIYRMVQKYSGDQSGNKKRFATFVYAKQSVDTGELESVATGGSNLYT
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the gammacoronaviruses M protein family.
Uniprot
EMBL
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
226
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
63.55027
Exp number, first 60 AAs:
30.43552
Total prob of N-in:
0.18045
POSSIBLE N-term signal
sequence
outside
1 - 23
TMhelix
24 - 41
inside
42 - 47
TMhelix
48 - 70
outside
71 - 79
TMhelix
80 - 99
inside
100 - 226
