Strain
Ferret_KX512809
(Region: USA: Michigan; Strain: Ferret enteric coronavirus strain FECV1, complete genome.; Date: 2015)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGATAGAGATAATACTGTTGTTTTGTTCTGTTATAGCATCTGTGGCGTCTGCCACTAGTGATGGTGTTAGACGCTATTGTTTAGCGAATAACACGAACACGAGTTCAACGGATTGTATTGATGAGGGAAGTCTTATTTGGCATCTTATGAACTGGAACTTCAGCTGGTCTGTGGTTTTAATTGTTTTTATTGCAATTTTGCAATATGGCAGACCGCAATTCAGCTGGTTCATGTATGGGGTTAAAATGCTAATCATGTGGTTCTTATGGCCTCTTGTTTTAGCGCTCACGATTTTTAACGCCTATGCTGAATTTAAAAGTTCTAGATATGTAATGTTCGGCTTTAGTGTAGCTGGTGCTGTGGTCACATTGGTTATGTGGGTTATGTATTTTGCAAGATCCATCCAATTATGGCGTCGTACCAGAACGTGGTGGTCTTTCAACCCTGAAACTAACGCCATACTATGTCTCAGTTCAGTAGGAAAGAGATTTGTTCTGCCATTAAACGGCGCTCCTACTGGTGTGACACTAACTTTGCTTTCTGGCAATTTATATGCTGAAGGTTTCAAAGTTGGAAGTGGTGTCAACGTTGACAATCTACCTAAATACATCATGGTGGCCACACCTGGTAACACAATTGTGTACCACCAGGTTGGAAAATCATTGAAAGCATCTAGTGCGACTGGATGGTCGTATTATGTTAGATCTAAAGCTGGCGATTACTCAACAGAAGCAAGACATGACAATTTGAGTGAACATGAAAAATTATTACATATGGTATAA
Protein
MIEIILLFCSVIASVASATSDGVRRYCLANNTNTSSTDCIDEGSLIWHLMNWNFSWSVVLIVFIAILQYGRPQFSWFMYGVKMLIMWFLWPLVLALTIFNAYAEFKSSRYVMFGFSVAGAVVTLVMWVMYFARSIQLWRRTRTWWSFNPETNAILCLSSVGKRFVLPLNGAPTGVTLTLLSGNLYAEGFKVGSGVNVDNLPKYIMVATPGNTIVYHQVGKSLKASSATGWSYYVRSKAGDYSTEARHDNLSEHEKLLHMV
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the alphacoronaviruses M protein family.
Uniprot
Pubmed
EMBL
Proteomes
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
260
Number of predicted TMHs:
4
Exp number of AAs in TMHs:
79.7176199999999
Exp number, first 60 AAs:
26.37627
Total prob of N-in:
0.33625
POSSIBLE N-term signal
sequence
outside
1 - 3
TMhelix
4 - 23
inside
24 - 43
TMhelix
44 - 66
outside
67 - 80
TMhelix
81 - 103
inside
104 - 109
TMhelix
110 - 132
outside
133 - 260
