CoVDB Coronavirus Database (v3)   
Strain
Human_TGEV_KX900394 (Region: USA;  Strain: Transmissible gastroenteritis virus strain TGEV/USA/HB/1988, complete genome.;  Date: 1988)
Gene
spike protein
Description
Annotated in NCBI,  spike protein
Location
KX900394(+):20365-24708
GenBank Accession
ASV64286.1
 

Sequence

CDS
ATGAAAAAACTATTTGTGGTTTTGGTCGTAATGCCATTGATTTATGGAGACAATTTTCCTTGTTCTAAATTGACTAATAGAACTATAGGCAACCATTGGAATCTCATTGAAACCTTCCTTCTAAACTATAGTAGTAGGTTACCACCTAATTCAGATGTGGTGTTAGGTGATTATTTTCCTACTGTACAACCTTGGTTTAATTGCATTCGCAATAATAGTAATGACCTTTATGTTACACTGGAAAATCTTAAAGCATTGTATTGGGATTATGCTACAGAAAATATCACTTGGAATCACAGACAACGGTTAAACGTAGTCGTTAATGGATACCCATACTCCATCACAGTTACAACAACCCGCAATTTTAATTCTGCTGAAGGTGCTATTATATGCATTTGTAAGGGCTCACCACCTACTACCACCACAGAATCTAGTTTGACTTGCAATTGGGGTAGTGAGTGCAGGTTAAACCATAAGTTCCCTATATGTCCTTCTAATTCAGAGGCAAATTGTGGTAATATGCTGTATGGCCTACAATGGTTTGCAGATGAGGTTGTTGCTTATTTACATGGTGCTAGTTACCGTATTAGTTTTGAAAATCAATGGTCTGGCACTGTCACACTTGGTGATATGCGTGCGACAACATTAGAAGTCTCTGGCACGCTTGTAGACCTTTGGTGGTTTAATCCTGTTTATGATGTCAGTTATTATAGGGTTAATAATAAAAATGGTACTACCGTAGTTTCCAATTGCACTGATCAATGTGCTAGTTATGTGGCTAATGTTTTTACTACACAGCCAGGAGGTTTTATACCATCAGATTTTAGTTTTAATAATTGGTTCCTTCTAACTAATAGCTCCACGTTGGTTAGTGGTAAATTAGTTACCAAACAGCCGTTATTAGTTAATTGCTTATGGCCAGTCCCTAGCTTTGAAGAAGCAGCTTCTACATTTTGTTTTGAGGGTGCTGGCTTTGATCAATGTAATGGTGCTGTTTTAAATAATACTGTAGACGTCATTAGGTTCAACCTTAATTTTACTACAAATGTACAATCAGGTAAGGGTGCCACAGTGTTTTCATTGAACACAACGGGTGGTGTCACTCTTGAAATTTCATGTTATACAGTGAGTGACTCGAGCTTTTTCAGTTACGGTGAAATTCCGTTCGGCGTAACTGATGGACCACGGTACTGTTACGTACACTATAATGGCACAGCTCTTAAGTATTTAGGAACATTACCACCTAGTGTCAAGGAGATTGCTATTAGTAAGTGGGGCCATTTTTATATTAATGGTCACAATTTCTTTAGCACATTTCCTATTGATTGTATATCTTTTAATTTGACCACTGGTGATAGTGACGTTTTCTGGACAATAGCTTACACATCGTACACTGAAGCATTAGTACAAGTTGAAAACACAGCTATTACAAAGGTGACGTATTGTAATAGTCACGTTAATAACATTAAATGCTCTCAAATTACTGCTAATTTGAATAATGGATTTTATCCTGTTTCTTCAAGTGAAGTTGGTCTTGTCAATAAGAGTGTTGTGTTACTACCTAGCTTTTACACACATACCATTGTTAACATAACTATTGGTCTTGGTATGAAGCGTAGTGGTTATGGTCAACCCATAGCCTCAACATTAAGTAACATCACACTACCAATGCAGGATCACAACACCGATGTGTACTGTATTCGTTCTGACCAATTTTCAGTTTATGTTCATTCTACTTGCAAAAGTGCTTTATGGGACAATATTTTTGAGCGAAACTGCACGGACGTTTTGGATGCCACAGCTGTTATAAAAACTGGTACTTGTCCTTTCTCATTTGATAAATTGAACAATTACTTAACTTTTAACAAGTTCTGTTTGTCGTTGAGTCCTGTTGGTGCTAATTGTAGGTTTGATGTAGCTGCCCGTACAAGAACCAATGAGCAGGTTGTTAGAAGTTTGTATGTAATATATGAAGAAGGAGACAACATAGTGGGTGTACCGTCTGATAATAGTGGTGTGCACGATTTGTCAGTGCTACACCTAGATTCCTGCACAGACTACAATATATATGGTAGAACTGGTGTTGGTATTATTAGAAAAACTAACAGGACGCTACTTAGTGGCTTATATTACACATCACTATCAGGTGATTTGTTAGGTTTTAAAAATGTTAGTGATGGTGTCATCTACTCTGTAACGCCATGTGATGTAAGCGCACAAGCAGCTGTTATTGATGGTACCATAGTTGGGGCTATCACTTCCATTAACAGTGAACTGTTAGGTCTAACACATTGGACAACAACACCTAATTTTTATTACTACTCTATATATAATTACACAAATGATAGGACTCGTGGCACTGCAATTGACAGTAATGATGTTGATTGTGAACCTGTCATAACCTATTCTAACATAGGTGTTTGTAAAAATGGTGCTTTTGTTTTTATTAACGTCACACATTCTGATGGAGACGTGCAACCAATTAGCACTGGTAATGTCACGATACCTACAAACTTTACCATATCCGTGCAAGTCGAATATATTCAGGTTTACACTACACCAGTGTCAATAGACTGTTCAAGATATGTTTGTAATGGTAACCCTAGGTGTAACAAATTGTTAACACAATACGTTTCTGCATGTCAAACTATTGAGCAAGCACTTGCAATGGGTGCCAGACTTGAAAACATGGAGGTTGATTCCATGTTGTTTGTTTCTGAAAATGCCCTTAAATTGGCATCTGTTGAAGCATTCAATAGTTCAGAAACTTTAGACCCTATTTACAAAGAATGGCCTAATATAGGTGGTTCTTGGCTAGAAGGTCTAAAATACATACTTCCGTCCCATAATAGCAAACGTAAGTATCGTTCAGCTATAGAGGACTTGCTTTTTGATAAGGTTGTAACATCTGGTTTAGGTACAGTTGATGAAGATTATAAACGTTGTACAGGTGGTTATGACATAGCTGACTTAGTATGTGCTCAATACTATAATGGCATCATGGTGCTACCTGGTGTGGCTAATGCTGACAAAATGACTATGTACACAGCATCCCTTGCAGGTGGTATAACATTAGGTGCACTTGGTGGAGGCGCCGTGGCTATACCTTTTGCAGTAGCAGTTCAGGCTAGACTTAATTATGTTGCTCTACAAACTGATGTATTGAACAAAAACCAGCAGATTCTGGCTAGTGCTTTCAATCAAGCTATTGGTAACATTACACAGTCATTTGGTAAGGTTAATGATGCTATACATCAAACATCACGAGGTCTTGCTACTGTTGCTAAAGCATTGGCAAAAGTGCAAGATGTTGTCAACATACAAGGGCAAGCTTTAAGCCACCTAACAGTACAATTGCAAAATAATTTCCAAGCCATTAGTAGTTCTATTAGTGACATTTATAATAGGCTTGACGAATTGAGTGCTGATGCACAAGTTGACAGGCTGATCACAGGAAGACTTACAGCACTTAATGCATTTGTGTCTCAGACTCTAACCAGACAAGCGGAGGTTAGGGCTAGTAGACAACTTGCCAAAGACAAGGTTAATGAATGCGTTAGGTCTCAGTCTCAGAGATTCGGATTCTGTGGTAATGGTACACATTTGTTTTCACTCGCAAATGCAGCACCAAATGGCATGATTTTCTTTCACACAGTGCTATTACCAACGGCTTATGAAACTGTGACTGCTTGGCAAGGTATTTGTGCTTCAGATGGTGATCGCACTTTTGGACTTGTCGTTAAAGATGTCCAGTTGACTTTGTTTCGTAATCTAGATGACAAGTTCTATTTGACCCCCAGAACTATGTATCAGCCTAGAGTTGCAACTAGTTCTGACTTTGTTCAAATTGAAGGGTGCGATGTGCTGTTTGTTAATGCAACTGTAAGTGATTTGCCTAGTATTATACCTGATTATATTGATATTAATCAGACTGTTCAAGACATATTAGAAAATTTTAGACCAAATTGGACTGTACCTGAGTTGACATTTGACATTTTTAACGCAACCTATTTAAACCTGACTGGTGAAATTGATGACTTAGAATTTAGGTCAGAAAAGCTACATAACACCACTGTAGAACTTGCCATTCTCATTGACAACATTAACAATACATTAGTCAATCTTGAATGGCTCAATAGAATTGAAACCTATGTAAAATGGCCTTGGTATGTGTGGCTACTAATAGGCTTAGTAGTAATATTTTGCATACCATTACTGCTATTTTGCTGTTGTAGTACAGGTTGCTGTGGATGCATAGGTTGTTTAGGAAGTTGTTGTCACTCTATATGTAGTAGAAGACAATTTGAAAATTACGAACCAATTGAAAAAGTGCACGTCCATTAA
Protein
MKKLFVVLVVMPLIYGDNFPCSKLTNRTIGNHWNLIETFLLNYSSRLPPNSDVVLGDYFPTVQPWFNCIRNNSNDLYVTLENLKALYWDYATENITWNHRQRLNVVVNGYPYSITVTTTRNFNSAEGAIICICKGSPPTTTTESSLTCNWGSECRLNHKFPICPSNSEANCGNMLYGLQWFADEVVAYLHGASYRISFENQWSGTVTLGDMRATTLEVSGTLVDLWWFNPVYDVSYYRVNNKNGTTVVSNCTDQCASYVANVFTTQPGGFIPSDFSFNNWFLLTNSSTLVSGKLVTKQPLLVNCLWPVPSFEEAASTFCFEGAGFDQCNGAVLNNTVDVIRFNLNFTTNVQSGKGATVFSLNTTGGVTLEISCYTVSDSSFFSYGEIPFGVTDGPRYCYVHYNGTALKYLGTLPPSVKEIAISKWGHFYINGHNFFSTFPIDCISFNLTTGDSDVFWTIAYTSYTEALVQVENTAITKVTYCNSHVNNIKCSQITANLNNGFYPVSSSEVGLVNKSVVLLPSFYTHTIVNITIGLGMKRSGYGQPIASTLSNITLPMQDHNTDVYCIRSDQFSVYVHSTCKSALWDNIFERNCTDVLDATAVIKTGTCPFSFDKLNNYLTFNKFCLSLSPVGANCRFDVAARTRTNEQVVRSLYVIYEEGDNIVGVPSDNSGVHDLSVLHLDSCTDYNIYGRTGVGIIRKTNRTLLSGLYYTSLSGDLLGFKNVSDGVIYSVTPCDVSAQAAVIDGTIVGAITSINSELLGLTHWTTTPNFYYYSIYNYTNDRTRGTAIDSNDVDCEPVITYSNIGVCKNGAFVFINVTHSDGDVQPISTGNVTIPTNFTISVQVEYIQVYTTPVSIDCSRYVCNGNPRCNKLLTQYVSACQTIEQALAMGARLENMEVDSMLFVSENALKLASVEAFNSSETLDPIYKEWPNIGGSWLEGLKYILPSHNSKRKYRSAIEDLLFDKVVTSGLGTVDEDYKRCTGGYDIADLVCAQYYNGIMVLPGVANADKMTMYTASLAGGITLGALGGGAVAIPFAVAVQARLNYVALQTDVLNKNQQILASAFNQAIGNITQSFGKVNDAIHQTSRGLATVAKALAKVQDVVNIQGQALSHLTVQLQNNFQAISSSISDIYNRLDELSADAQVDRLITGRLTALNAFVSQTLTRQAEVRASRQLAKDKVNECVRSQSQRFGFCGNGTHLFSLANAAPNGMIFFHTVLLPTAYETVTAWQGICASDGDRTFGLVVKDVQLTLFRNLDDKFYLTPRTMYQPRVATSSDFVQIEGCDVLFVNATVSDLPSIIPDYIDINQTVQDILENFRPNWTVPELTFDIFNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIETYVKWPWYVWLLIGLVVIFCIPLLLFCCCSTGCCGCIGCLGSCCHSICSRRQFENYEPIEKVHVH

Summary

Uniprot
A0A222UC54  
EMBL
KX512809    ASR18938.1   
Pfam
PF01601   Corona_S2
PF01600   Corona_S1
Interpro
IPR002552   Corona_S2
IPR002551   Corona_S1
ProteinModelPortal
A0A222UC54  
PDB
6U7K     E-value=0.0     Score= 979     Identity=42.62%     Cov(Q)=98.27%     Cov(P)=101.64%
3D Structure

Ontologies

GO
GO:0046813  P:receptor-mediated virion attachment to host cell
 GO:0019064  P:fusion of virus membrane with host plasma membrane
 GO:0016021  C:integral component of membrane
 GO:0019031  C:viral envelope

Subcellular Location

From MSLVP
Host nucleus. Host cytoplasm.

Topology

Length:
1447
Number of predicted TMHs:
1
Exp number of AAs in TMHs:
43.2498699999999
Exp number, first 60 AAs:
0.05553
Total prob of N-in:
0.00336
outside
1  -  1386
TMhelix
1387  -  1409
inside
1410  -  1447
 
 
Copyright@ 2018-2023    Any Comments and suggestions mail to:  zhuzl@cqu.edu.cn, mg@cau.edu.cn   渝ICP备19006517号

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