Strain
Human_TGEV_KX900410
(Region: USA: Minnesota; Strain: Transmissible gastroenteritis virus strain TGEV/USA/Minnesota153/2014, complete genome.; Date: 4-Feb-14)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGAAGATTTTGTTAATATTGGCGTGTGCGATGGCATGCGCATGTGGGGAACGCTATTGTGCTATGCAAGACACAGGTTTGTCATGTCGCAATAGCACAGTGTCTGCTTGTGAGTCATGCTTCAACGGAGGCGATCTTATTTGGCATCTTGCAAACTGGAACTTCAGCTGGTCTATAATATTGATCATTTTTATTACTGTGCTACAATATGGAAGACCTCAATTCAGCTGGTTCGTGTATGGCATTAAAATGCTTATAATGTGGCTATTATGGCCCATTGTTTTGGCTCTTACGATTTTTAATGCATACTCGGAATACCAAGTTTCCAGGTATGTAATGTTCGGCTTTAGTATTGCAGGTGCAATTGTTACATTTGTACTCTGGATTATGTATTTTGTAAGATCCATTCAGCTATACAGAAGGACTAAGTCCTGGTGGTCCTTCAACCCAGAAACTAATGCAATTCTTTGCGTTAGTGCATTAGGAAGAAGCTATGTGCTTCCTCTCGAGGGTGTGCCAACTGGTGTCACTCTAACTCTGCTTTCAGGGAATTTATACGCTGAAGGGTTCAAAATTGCCGGTGGTATGAACATCGACAATTTGCCAAAATATGTAATGGTTGCATTACCCAGCAGGACTATAGTCTACACACTTGTTGGCAAGAAGTTGAAAGCAAGTAGTGCGACTGGATGGGCTTACTATGTAAAATCTAAAGCTGGTGATTACTCAACAGAGGCAAGAACTGATAATTTGAGTGAGCAAGAAAAATTATTACATATGGTATAA
Protein
MKILLILACAMACACGERYCAMQDTGLSCRNSTVSACESCFNGGDLIWHLANWNFSWSIILIIFITVLQYGRPQFSWFVYGIKMLIMWLLWPIVLALTIFNAYSEYQVSRYVMFGFSIAGAIVTFVLWIMYFVRSIQLYRRTKSWWSFNPETNAILCVSALGRSYVLPLEGVPTGVTLTLLSGNLYAEGFKIAGGMNIDNLPKYVMVALPSRTIVYTLVGKKLKASSATGWAYYVKSKAGDYSTEARTDNLSEQEKLLHMV
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the alphacoronaviruses M protein family.
Keywords
Glycoprotein
Host Golgi apparatus
Host membrane
Membrane
Transmembrane
Transmembrane helix
Viral envelope protein
Viral matrix protein
Virion
Feature
chain Membrane protein
Uniprot
Pubmed
EMBL
PRIDE
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
From Uniprot
Virion membrane
Largely embedded in the lipid bilayer. With evidence from 1 publications.
Host Golgi apparatus membrane Largely embedded in the lipid bilayer. With evidence from 1 publications.
Host Golgi apparatus membrane Largely embedded in the lipid bilayer. With evidence from 1 publications.
Topology
Length:
261
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
69.9640399999999
Exp number, first 60 AAs:
13.81861
Total prob of N-in:
0.31430
POSSIBLE N-term signal
sequence
outside
1 - 45
TMhelix
46 - 68
inside
69 - 74
TMhelix
75 - 97
outside
98 - 111
TMhelix
112 - 134
inside
135 - 261
