CoVDB Coronavirus Database (v3)   
Strain
Bat_KY073745 (Region: Kenya;  Strain: NL63-related bat coronavirus strain BtKYNL63-9b, complete genome.;  Date: 21-Jun-10)
Gene
N protein
Description
Annotated in NCBI,  N protein
GenBank Accession
Full name
Nucleoprotein      
 

Sequence

CDS
ATGGCAACTGTCAATTGGGCCGACGAATCCGATAAAGGCAATGGAAGAGGTGGGCGTGGTAGGAGAGGTCGCATCGACCCCTCTTATTACTCCCCTATCATTGTCGAAGGAAATGAAAAGCCCTGGAATGTCATCCCTAAAAACTTTGTCCCAAAAGGAAAAGGTGGAAAGGATGAACAAATTGGCTATTGGAATGAGCAACCACGCTGGCGCATGCGCAAAGGCGAAAAGGTTGAACTTCCCTCAAAGTGGCACTTTTACTATCTTGGAACTGGTCCCCAAAGCAAACTTAAATTCAGAGAGCGCGCTCAAGGCGTTGTCTGGGTTGCAGTCAATGGGGCCAAAACAGCTGACACCGGGCTTGGTACTCGCAAGAGAAACCAACAACCCATTGTTCCCACTTTTGATGTCAAAATCCCTTCAAACATCACCATTGTTGAGGACCATGATCGGTCTGCACCCAGCTCTCGTAGCCAAAGCCGTGGTCGATCTCAATCCCGCAATGACAACCGTTCCAACAATCAGTCTCGCAACCAGTCGCGTAACAACTCGCGATCTAGGTCCAACTCACGTGGTCGATCCGGAAATCCCACATCCCCGGACGATCTTGTTGCTGCTGTGCGAGCTGCTCTGGAGGGCATGGGCTTCGAACCCATCAAGAACGGTCAAAGTGGAAAGAACACTCCAAAGAGTGGTAATGCCACACCCAAAAAGCAGAAATCCCGTGCTTCATCACCTGCTCCTCGTCCAGCTTCTCCAAAGAAGCAAATGGACAAACCAAGATGGAAGCGCACACCAAATCAGGAAGAAGATGTCGTGAAGTGCTTCGGCCCTCGCGATTTCGACCACAACTTTGGTGACTCTGAGATTGTTCGTCTCGGAGTTGAAGCGCCACACTATCCACAGCTTGCCGAACTTGTGCCCTCACAGGCTGCTTTGCTGTTTGATAGTAACATTTCCACCAAGGAGCTGAAAGATCAGGTGATGATCACTTACACCTATAGTATGCTTGTGCCCAAAGACAACAAGCACCTAGGTCCTTTCCTGCAGCAAGTTAATGCTTTCGCTGATGGCGACAAAGTTCCAGCCCTGCCGCCAAAAGTGAAACGCCAAAAGTCCAAGACTGAAAAGAAAGATGACGTCCTGGATGGTCTGAATATTGCTGCCCCTGCTTTTGAGCCAAAAGAACAGCGCGAATCGCGCCCACTCAAGTTTTCTGAAGTTGCCAAAAATGCCGTCGACCCGCTCAATGAGCTGAAGGTCGAAATGGTAGATGAGGTTAAGTATGAGTCTTCTGCTTAA
Protein
MATVNWADESDKGNGRGGRGRRGRIDPSYYSPIIVEGNEKPWNVIPKNFVPKGKGGKDEQIGYWNEQPRWRMRKGEKVELPSKWHFYYLGTGPQSKLKFRERAQGVVWVAVNGAKTADTGLGTRKRNQQPIVPTFDVKIPSNITIVEDHDRSAPSSRSQSRGRSQSRNDNRSNNQSRNQSRNNSRSRSNSRGRSGNPTSPDDLVAAVRAALEGMGFEPIKNGQSGKNTPKSGNATPKKQKSRASSPAPRPASPKKQMDKPRWKRTPNQEEDVVKCFGPRDFDHNFGDSEIVRLGVEAPHYPQLAELVPSQAALLFDSNISTKELKDQVMITYTYSMLVPKDNKHLGPFLQQVNAFADGDKVPALPPKVKRQKSKTEKKDDVLDGLNIAAPAFEPKEQRESRPLKFSEVAKNAVDPLNELKVEMVDEVKYESSA

Summary

Function
Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.
Pfam
PF00937   Corona_nucleoca
Interpro
IPR037179   Nucleocapsid_C
IPR001218   Corona_nucleocap
IPR037195   Nucleocapsid_N
SUPFAM
SSF103068   SSF103068
SSF110304   SSF110304
ProteinModelPortal
PDB
5N4K     E-value=2e-51     Score= 169     Identity=54.79%     Cov(Q)=33.72%     Cov(P)=97.33%

Ontologies

Subcellular Location

From MSLVP
Host nucleus > host nucleolus. Host cytoplasm. Secreted.
From Uniprot
Virion  
Host endoplasmic reticulum-Golgi intermediate compartment  
Host Golgi apparatus  

Topology

Length:
433
Number of predicted TMHs:
0
Exp number of AAs in TMHs:
0.0024
Exp number, first 60 AAs:
0
Total prob of N-in:
0.00949
outside
1  -  433
 
 
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