Coronavirus Database

Strain

Porcine_LT900503 (Region: Germany; Strain: Porcine torovirus isolate PToV_GER_L00926-K20_14-01_2014 genome assembly, complete genome: monopartite.; Date: )

Gene

membrane protein

Description

Annotated in NCBI, membrane protein

Location

LT900503(+):25497-26198

GenBank Accession

SNT95685.1

Full name

Membrane protein

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGTTTGATACAAACTTTTGGCCTTTTCCAGACCAGGCCCCAGACCCTTTTAAAGCCCAGGTTGAGCAGTTGTCATCTACTGAAAATGTTTATATTTTTCTTACTACACTTTTTGGTATATTGCAATTGGTTTATGTTATTTTTAAGCTATTATGCACAATGTTTCCAACATTGCATTTTTCACCAATTTGGAGGGGTTTGGAAAATTTTTGGCTTTTTCTTAGCCTTACATCTTTGGCGATTGCTTATTGGTGGCTTCCTAGTATGACTTTTACCGGCTACTGGGCACTTACAGCAATTGCCACCGTTTTAGTTTTAGTTATGTTAATTATGATGTTTGTTAAGTTTGTTAATTTTGTTAAGTTGTTTTATAGAACTGGTAGCTTTGCAATTGCTGTTCGTGGTCCTATTGTTTTAGTAGCCCTTGATGTGACCATCAAGCTACATTGCACACCTTTCGCAATTTTAGTTAAAGAAGTTGGCAGCATTTTTTATCTTTCTGAGTATTGTAACAAACCATTGAATGCAGCCCAAATTGCTGCACTTAAGATTTGTGTTAACGGACAATGGTTTGCCTACACTAGATCATCAACTACAAGTGCTGCAAAAGTTGCAGCTGCAAATAGTACTGCCAAATATCATCTTTTTATTCTTCAAGGTGTTGCAGATTATACACAATTGTCAAGTGTAAAGTTTGAGTAG

Protein

MFDTNFWPFPDQAPDPFKAQVEQLSSTENVYIFLTTLFGILQLVYVIFKLLCTMFPTLHFSPIWRGLENFWLFLSLTSLAIAYWWLPSMTFTGYWALTAIATVLVLVMLIMMFVKFVNFVKLFYRTGSFAIAVRGPIVLVALDVTIKLHCTPFAILVKEVGSIFYLSEYCNKPLNAAQIAALKICVNGQWFAYTRSSTTSAAKVAAANSTAKYHLFILQGVADYTQLSSVKFE

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus (By similarity).
Interacts with many viral proteins in infected cells. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in the viral mRNA packaging into the virus (By similarity).

Similarity

Belongs to the torovirinae M protein family.

Keywords

Host Golgi apparatus Host membrane Membrane Reference proteome Transmembrane Transmembrane helix Viral envelope protein Viral matrix protein Virion

Feature

chain Membrane protein

Uniprot

A0A239QPW0 Q70KN6 Q70KN9 A0A097P9L3 D2K6D8 A0A513QA15 + More
D2K6C8 U5IJ81 Q70KN7 A0A481ZJZ2 D2K6D4 A0A513Q9X6 D2K6D5 C1J1E2 V5J424 A0A060L1F8 A0A513QA03 A0A3G1RGD1 P27904 A0A1X9H814 A0A481W694 A0A3G4S8L7 Q70KN2 A0A3G4S8J8 O90305 A0A0U5AKT7 A7BI34

Pubmed

12915570 20558206 24122107 24903213 2024492 9879765 + More
16137782 26708248 17567770

EMBL

LT900503 SNT95685.1 GU181245 AJ575369 AJ575371 ACZ71740.1 + More
CAE01335.1 CAE01337.1 AJ575368 CAE01334.1 KM403390 AIU41586.1 GU181250 MK379077 MK379137 MK379161 ACZ71745.1 QBJ02014.1 QBJ02092.1 QBJ02120.1 MK379131 QBJ02083.1 GU181240 GU181241 GU181242 GU181243 GU181244 ACZ71735.1 ACZ71736.1 ACZ71737.1 ACZ71738.1 ACZ71739.1 JQ860350 AGB05583.1 AJ575370 CAE01336.1 MH603532 QBK95469.1 GU181246 GU181248 KF727581 KF727582 HG764767 HG764768 ACZ71741.1 ACZ71743.1 AIC65787.1 AIC65788.1 CDJ80035.1 CDJ80036.1 MK379100 QBJ02042.1 GU181247 GU181249 MK379062 MK379166 ACZ71742.1 ACZ71744.1 QBJ01994.1 QBJ02128.1 FJ232069 ACO48289.1 JQ740196 AFZ75472.1 KF727566 KF727567 KF727568 KF727569 KF727570 KF727571 KF727572 KF727573 KF727574 KF727575 KF727576 KF727577 KF727578 KF727579 KF727580 KF727583 KF727584 HG764752 HG764753 HG764754 HG764755 HG764756 HG764757 HG764758 HG764759 HG764760 HG764761 HG764762 HG764763 HG764764 HG764765 HG764766 HG764769 HG764770 AIC65772.1 AIC65773.1 AIC65774.1 AIC65775.1 AIC65776.1 AIC65777.1 AIC65778.1 AIC65779.1 AIC65780.1 AIC65781.1 AIC65782.1 AIC65783.1 AIC65784.1 AIC65785.1 AIC65786.1 AIC65789.1 AIC65790.1 CDJ80020.1 CDJ80021.1 CDJ80022.1 CDJ80023.1 CDJ80024.1 CDJ80025.1 CDJ80026.1 CDJ80027.1 CDJ80028.1 CDJ80029.1 CDJ80030.1 CDJ80031.1 CDJ80032.1 CDJ80033.1 CDJ80034.1 CDJ80037.1 CDJ80038.1 MK379125 QBJ02074.1 MG996765 AWV66920.1 X52505 KR527150 ANA57417.1 MK521914 QBJ04616.1 MG957146 AYU75162.1 AJ575374 AJ575375 AJ575376 AJ575377 CAE01340.1 CAE01341.1 CAE01342.1 CAE01343.1 MG957145 AYU75158.1 AF076621 AY427798 LC088094 LC088095 BAU21407.1 BAU21413.1 AB285126 BAF75424.1

Proteomes

UP000269215 UP000119381 UP000111898 UP000006571 UP000207672 UP000000355 + More
UP000102793 UP000138412

Pfam

PF10943 DUF2632

Interpro

IPR024251 M_Torovirus

ProteinModelPortal

A0A239QPW0 Q70KN6 Q70KN9 A0A097P9L3 D2K6D8 A0A513QA15 + More
D2K6C8 U5IJ81 Q70KN7 A0A481ZJZ2 D2K6D4 A0A513Q9X6 D2K6D5 C1J1E2 V5J424 A0A060L1F8 A0A513QA03 A0A3G1RGD1 P27904 A0A1X9H814 A0A481W694 A0A3G4S8L7 Q70KN2 A0A3G4S8J8 O90305 A0A0U5AKT7 A7BI34

KEGG

vg:17603138 vg:3707769

GO

GO:0016021  C:integral component of membrane
GO:0019031  C:viral envelope
GO:0039660  F:structural constituent of virion
GO:0044178  C:host cell Golgi membrane
GO:0055036  C:virion membrane

From MSLVP

Host nucleus. Host cytoplasm.

From Uniprot

Virion membrane Largely embedded in the lipid bilayer. With evidence from 1 publications.
Host Golgi apparatus membrane Largely embedded in the lipid bilayer. With evidence from 1 publications.

Length:

233

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

76.22209

Exp number, first 60 AAs:

21.60052

Total prob of N-in:

0.02141

POSSIBLE N-term signal

sequence

outside

1 - 28

TMhelix

29 - 51

inside

52 - 62

TMhelix

63 - 85

outside

86 - 94

TMhelix

95 - 117

inside

118 - 233

Sequence

Summary

Ontologies

Subcellular Location

Topology