Strain
Mink_MF113046
(Region: China; Strain: Alphacoronavirus Mink/China/1/2016, complete genome.; Date: 2016)
Gene
membrane protein
Description
Annotated in NCBI,
membrane protein
Location
GenBank Accession
Full name
Membrane protein
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Matrix glycoprotein
Membrane glycoprotein
Sequence
CDS
ATGGAGGTGTTATTGGTAGCAGCAACTGCTGTGTTGTCTGCCATACCAACTAGCCATGCAGAAAACTTGTATTGTCTTATGAACACAACTGATGGTGCTAATATGACTTGTCAAAATAGTTCTGGTAGCTGCACTAGTTGTATTAATGAAGGAAATCTTATATGGCATTTAATGAACTGGAATTTCAGTTGGTCTGTTCTTCTCATCTTGTTTATAACAATATTACAATATGGAAGGCCGCAGGTCAGCTGGTTCATTTATGGTATTAAAATGCTTATCATGTGGCTTTTGTGGCCACTGGTTTTAGCACTCACGATTTTTAATGCCTATTCTGAATATATGAATTCCAGGTATGTAATGTTTGGCTTTAGCGTAACTGGTGCTGTACTCACATTTATTTTGTGGGTTATGTACTTTGTTAGATCCATCCAATTATGGCGCCGTACTCGCACATGGTGGTCATTCAACCCTGAGACAAATGCGATCCTGTGTCTTAATGCTGTGGGAAACCGATTTGTCTTACCTTTGAATGGAGCACCAACTGGTATTACATTAACTTTGCTCTCTGGCAACTTGTATGCAGAAGGGTTCAAAGTCGGAGGTGGCGTGAATGTAGAAAATTTGCCTAAGTATGTAATGGTAGCAACACCTGGTAATACCATTGTCTATCATCAAGTGGGCAAGTCCCTCAAGGCTGCAAATTCTACTGGATGGTCTTATTATGTTCGTGCTAAAGCAGGCGATTACTCAACAGAAGCAAGAAATGACAATTTGAGTGAGCATGAAAAATTATTACATATGGTATAA
Protein
MEVLLVAATAVLSAIPTSHAENLYCLMNTTDGANMTCQNSSGSCTSCINEGNLIWHLMNWNFSWSVLLILFITILQYGRPQVSWFIYGIKMLIMWLLWPLVLALTIFNAYSEYMNSRYVMFGFSVTGAVLTFILWVMYFVRSIQLWRRTRTWWSFNPETNAILCLNAVGNRFVLPLNGAPTGITLTLLSGNLYAEGFKVGGGVNVENLPKYVMVATPGNTIVYHQVGKSLKAANSTGWSYYVRAKAGDYSTEARNDNLSEHEKLLHMV
Summary
Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the alphacoronaviruses M protein family.
Uniprot
Pubmed
EMBL
Pfam
PF01635
Corona_M
ProteinModelPortal
Ontologies
GO
Subcellular Location
From MSLVP
Host nucleus. Host cytoplasm.
Topology
Length:
268
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
74.7892799999999
Exp number, first 60 AAs:
11.25925
Total prob of N-in:
0.28531
POSSIBLE N-term signal
sequence
outside
1 - 52
TMhelix
53 - 75
inside
76 - 81
TMhelix
82 - 104
outside
105 - 118
TMhelix
119 - 141
inside
142 - 268
