Strain
Porcine_MF280390
(Region: China; Strain: Porcine deltacoronavirus strain CHN-GD-2016, complete genome.; Date: 2016)
Gene
ORF1a protein
Description
Annotated in NCBI,
ORF1a protein
Location
GenBank Accession
Sequence
CDS
ATGGCCAAGAACAAGTCCAAGCGTGACGCTATTGCGTTGCCTGAAAATGTACCACCACCTCTGCAACTTTTCATTCACGTTGCAGCTGCTGAAGAGGGTCACTCTAAGGTTACTACTTACCTTGGCAACTATAACCTCTATGCCACCAAGGCTCCGCCTGGCGTGCAGGTTCTTAGTGCTAAAACCTCTCTTACTGACTTTGAGAATGTCTTTGGAGCCCAACCCACCTTGCGATCAATTCGTAATCTGGTTTGTGAGGCTCGCTCGGCTGAATGGACAACTTCCAAGAATGCTTTTGCACTCAAAGCCACTCAACTTGACTACTCTGATGCCGTTTTGAGGGCAATGATTCGTTTCTGCCCTCCAAAGGTGTCCACACTCGCTGCCTTTGCTCTTTTTGGCCGATTGGTTAAAATTGAGGACAAGGAACTTGCTGAGTTAGCTCGTGATACTGCCCTTGAGTTGGCGTACACGGCTAAAATTGGTACATCTCTTGCTGACACGAGATCTGTCTCACTTATTCATAAGGACGCTTATCTAACTCTCAGTAATGAGGTTGTTGGCGTAACTTTTACTGCCGCACTTATGGCAAAGGCTACCACTGTTAATGGAGCAATGCAATACTCAAACTTTTACCTCTACCCTCGTGCCACTATTAAGGTGACCGATGGTAAGGCTGAAGCAATTGCAACTAAGCCTCTGCCTGCTGCCACTAAAGGCAAGCCAATCACAGAGGATGTCAACCTTCTCCCTGACTATCAGCAGCTGCTTGTTGATCAAGTGACTGGCACTGAGGTTAAGGTTGGAGCTCTAACCTATGTTAAAACCACTGATACACCACCCCTTTACTTTCCCAAAGTCAAGGGTGGTGTTATTGGTATTGCACTTAAGCAGCAGGGCACTGCGGCTAAGAAGCTCAATGTAGTCTTCCATGCTCAACCTGATGATGTTCTGCTAGCCTTCATACAACTTCAGCAATTCTTGAACCGTACTTCGGATTCAAGTGTTGAAATTACTGACTGCCAGAGTTATGAAGTATCTCCAACTGTGACGGTCAAAATTGGCCCGTCTAAACCTGGGGATGTCATCGTGGCTACTGATGAGGAATACCTTAAATGCTTTGAAACCCCTGAGGTAGGTAGGCTCTATAAGGTTTTCCAAACTCAATCTTGGGCTATCATTGAGCGTGCCTTCTCCAGTATGAAGATCCGCGTGTCCAAAGCTTTATCAGCATTTATAAGTTTTCTGCAAAACCTTGCAGATAACTTTACTGCAATAAGTGGTGTTGTCACTGCACTCATTCGTGAACTCCAGGATCTTACCCTGGATGTGGCGACACGTATCACTAACATACAATTTGTTTACCGTGCCGGTAAGCTTATTGTCGACACGACAAGTGTCATAGCTAAACTTTTCCAGCCATTTTGTGATTTTATATCACCTTTCCTTCGGAAAGTTGCTGGTTTTGCAATTTACACTGTTGGTAATCGCATGCTTATGTTTACCAGCACTGGCACCTTTCTTCTCACAAAGGCAACTACTAAGATACTCAATAAGGCAAAGTACATCTTTGATGTGGAGCCTGAGTACCCAGTAGATGTAACAACATCCAAAGTTGTAGTACATGAAGCACTCCAGCAAATCGACACTAAGCCTACTAGAGCTCTAGAGGCTGTTGATGTCGTTGTTGGTAATACTGTACTGCAAATGGCTACTGATGGCACTGCGTTCTACCCATCGGATGGTACGCACGCCTCTCTTCCAGGATTCAAAGCAGGCTCGGATGAGCTTTTTATAAGCTTCAACTGCGACCTCTTTGATGATGAGACTAATGCTCAAATCAACGAAACACTCGCTGCATATGAGCTTAACCAACTAGTGGCTCCAGGTGATTCTACACCGCGTCAAATTGCGACATTGGTTGTCGATACACTTGCAGATGCTATAACAGACCACTTTCCGGAGAAAACCATTGATCTACCTGAAGACTATCAAGTCTTTTCTGACCATGATGACCTCCCACTCGCACAATACCACATCCCTGATCACCTGAGCCTGTATATTCAGGCTATGGAAGGTGAAGATGATAGTGGTGATGAAATATGTATTGAGGACGATGATTACGACTGTCCTCAAGCTGACGAAGACACAGAAGGAGTAATTCCCCAACAGTGGGAACTTCCTGATGTTGATAAATTTTTACTCAAGATCCAGGAACGGAAGACCAGCAGCGACGAAGTACTTAGCGTCGACGTCTATCCTAAACCAGAGCCGGTCGGCAATGTTGGGATTGACGACAGCGCGTCGGAAAAGAAGCCAAATGGGGACCCAGTACCGGATCCTGAGGTCCATCCAACACTAGAGAGTGTGGATGTTGAACGACCAATCGAAACAGCAAACCAGGCTGTTGAATACAAACCTTCTGATACCACCTTTGTGGTTGATGAGGAACAATTACAAGAATCAACACCAGAACATGAACTCCGCTCCTATGAAGGAGAGTTTGATTCTGATGATGAAATTATTATTCCTATAGTACCAGTAACACCTGCGGATTTAAAACCACAGACTATTACTATAAAGGAGTACTTTAAGTCTGAAAAACTTGAGACTATTAACGAAGGATCCACAGAGTCAGTTACACAATCTGACGATTCGTTCGACGAGTCATTTGTTGATGCTGAGTCTGATGATCCACAAGATCCTGCTGTATATGATGATACAACAATTATAACGGACAGCACTGATGTAGGCGATGAGCCTGAGACAACTCTAGCTACCATCGTTAACACACCTCTGACACTCGATAATAACTTGCCACCTGAAGCCATTAAACAACCCAGCCCGACTAAGGTTGAGTTAGTTGTTGGTGAATTGGCAAGTATTAAATTTGACAATTCTGTCCTAGTCAACCCTGCTAATGCGCAATTAACAAATGGCGGTGGAGCTGCCCGTGCAATTGCAAAATTAGCTGGTCCAAAATACCAAGAGTACTGTAATAGTGTGGCTCCTATCTCAGGACCGCTTACCACGGACTCTTTTGATGCCAAGAAACTTGGTGTAGCCTGCATCTTGCATGTAGTGCCACCCAAAGGTTCTGACCCTAATGTACAAGAACTCCTGTATCAAGCTTACAAGAGTATCCTTACTGAACCAGCACACTATGTTATACCTATACTAGGTGCTGGTATCTTTGGATGCAACCCAGTCCACTCTCTGGATGCGTTCAGGAAAGCATGTCCAAGTGACATAGGTCGTGTCACCCTTGTCACTATGAACAAAAACCATTTGCAGGTGTGGGATGCTCTCAATAGAACCATTGTACGCACCACTACTGACTATGATCAAGTTACCACCAAGGCCCTTACACCCCAGGGAGTGTTAGAAGCCAATCTCTTTGATGGTGAGGACTTTGTTCAAGAACCAAAACCCGGTCAAATCTACCTTGAGGTTACTGAAGAAGTTCAGAACCAAGCCAAGGAACTTGACCTTAACCTTCAGCAATATTGTGTCTACCTGAAGACTTGCCACCATAAATGGGTTGTGAGTCGTATGAACGGGTTGATGCATCTAAAACAAAAAGATAACAATTGTTTTGTTAGTGCAGGTGTAAACCTGTTTCAAAACACTGCTTATCAACTTAGACCTGCTATTGATGCTCTCTATAGGGAGTATCTCAATGGTAATCCAAACAGATTTGTTGCTTGGATCTACGCATCCACTAACCGTCGTGTTGGTGAGATGGGTTGTCCACAGCAAGTTATTTCTTTGCTCGTTAGTAACTCTGACGCAGCATTTTCAGCAACTACAGCCTGTTGTAACACCTACTTTAACCACACAGGTGTTATTTCAGTAGCTCGTGAATATGACCCAATACAACCAAAGGTCTACTGCATGAAGTGTGATGTGTGGACTCCCTTTACACCCCAGAGTGGAAAAGGTGCAGTTGCAATTGGTACTTCTGCAGATGAACCTACAGGTCCTGCCATTAAATTTGCCGCAGCTCACTGCTGGTACACTAATGGCAAGAAAACAGTTAATGGCTATGACACTAAAGCTAATGTTGTAGCTACTTATCATAGGTTTGACGTGCCTAAGCCTCAACTTGTCGAGGACGTGGTTGCGCTGCCTACTAAAAATGACTTTGAAGTTCTCAATGTTGAAGAACTGCCACAGGATAGTGTGCTCCATTTGGACCCACCTCCTGTACAGGCCTTACAACCTAAGGCTAACCAACACATTGAGATTTTAGAAAACCCAGATTATCTGGACATTTTGGATCTTTGGATTCGTAAACCCAAATTCATCCTCGTAAAGTCGTGGAGTGTTTTGGGTAGAGCACTATGTAAGGCAGGTAAAGTTGTCTTTGTCAGTGCTTCGCTTTTGACCCGTTTTTACAATTACCTTGTAGAGATTGGTGCTCTTGACTCAACAATAAGGTTGTCAGTCGATCTTACCTGTAAATTTGTTAGAACGGTACTCCCATCGTCTAACACTGTACACAAAACTTGTCTTGGTCTGTATTATTCAGCCCAGACACTTTTTGTTTCTTTAGCACCATTCCTTATGTTACCAGCTGTAGTTAGTCTGCTTAATTCAGGCTATACAATTGGCACATATTTGTATGCAAAAACTGGCTGGCCTTGTAATTACAATGCCACGCAACACTTTGATTATAATTCTTACTGTGCAGGTGACTTGGTTTGTCAAGCCTGTTTTGACGGTCAAGACTCCCTACATTTGTATCCGCATTTACGTGTTAATCAGCAGCCCCTTCAGACCACTGACTACACTGTTTATGCGCTTTCACTAATACTACTATTAGCTAACATGACTCTTGTCATGGGCACGCTAATAGTTACCTTCTTTGTGAACTTCTATGGTGTGCAAATACCATTTTATGGTACACTTCTGATAGATTATCAGTCCGCGCTGATGATGACTTTCTCAGTGTACTACTTTTATAAGGTAATGAAGTTTTTCCGCCATCTCACACATGGATGTAAAATTCCAACGTGTATGGTATGTGCTAAACTTCGTACCCCACCTACTATAACAGTTGAGACTGTCGTTCAAGGCAGGAAATACCCATCTGTTATTGAAACAAATGGCGGGTTTACAATTTGTAAAGAACACAACTTCTATTGCAAAGACTGCTCTCTACAAACACCCGGCACTTTCATCCCGACAGAAGCTATTGAGTCGCTCTCACGAGCTACCAGGCTTAGTGTCAAACCAACAGCACCAGCATTCTTACTTGCTAGAGATGTTGAGTGCCAAACTGATGTTGTCGTTGCTCGCGCAATGCATAACCAAAATGCGCATGTGTGCATTTCAAAATACTCTGATATCCGTACCGTTGACCAACTACTTAAGCCTACTCCACTGTTTTCATACACTCCCGATGTTATCATCGCGGCAGACTTTGACAACAGAGGTAGTCTTAAGACAGCTAAAGAATTAGCTGTGGTTTTGTCAATGGACCTTAAACGTACTATAATTATCATTGATCAGGCCTATTCTAGACCCATTGACAATTATCAGGAAGTTGCTTCTCGTATTGAGAAGTATTACCCAGTTGCAAAGATTACACCCACAGGTGACATCTTTACAGACATTAAGCAAGCGACCAATGGCCAAGCTAGTGACTCTGCTATTAATGCAGCTGTTCTGGCTGTCCAGCGCGGTCTTGATTTTACAATTGACAACCCTAACAATATATTACCACATTACGCCTTTGACTTTTCAACCCTCAATGCAGAAGACCAGTCTACCATTTTGGAGAGTGGTTGTGCTAAAGGCAATCTCAAGGGCACTAATGTTGGTGTTGTTCTTTCAGCTAGCCTTGTTACACGTCTTAGTCAGCAGGCTATACGTGTGATTGCTAATGCTGCTTCACGTAATGGTGTAACATGCGCTGTTACTCCATCTACACTTGTTATGCGTGGGAATATTGCAACACAGCCCTTGACTCGCATCAAAGCTGGTGCACCTCCCATGCGTCAAAAAATTTTATGTGTTATCCTGGCACTTGCTATTGTGTACTTTGCTGCTATGGCTTTTGGCTTTTTGGCAAGTCAAATTACGCTTAATACAGTGCCTACGATTAAATCTGATATCCGCGCCTCTACCTTCTACGTTGTTAGAGATGGAGTCTTGGATACTGTTCGCTCAAATGACAAGTGCTTTGCAAATAAGTTTTTGGCATTTGATAGCTTCATTCAAGCACCTTACACTAATTCACCTGACTGTCCAGTCGTTGTGGGAGTTGTTGAAGTAACGACGCACTCTATTCCTGGAATTCCAGCAGGTGTCATTCATAGAGATGGTCTCATACTTAACATTTATGAACAGTCTCTTTATGAAACCCATCAGCGTCAGTCTATGGTTAGGGATGCGTTGTCACTCAAGACAGCAAATCTCTTTAACCTAGGCAAGCGTGTTGTAGTAGGATACACTCAACATGAAGTTGTTGTGGGTACCTCCTATTTTAATTCTCCTGCACTTTTTAACGCAAAGTGCACCTTCTTACAGTATCAGGACACTAGACAACTCTATTGCTATGATACTGTTCCTACTGAACATAAGCTTTACTCTGATGTGCTTCCGCACGTCGAGTATAAGGCTATTGACATTAATGGTGATCTTGTTCCTTTCAAGATACCGGAGCAGATAATGTTCTATCCACATATTGTGCGCTATACTAGCAATTCCTATTGCCGTATGGGGCATTGTTTTAATACTAACCCTGGTATTTGCATTTCATTTACGGACGAATTTCCGTATAGTGAAAATGTTAAACCCGGTGTATACTGTGCTGATACCTCTTTGCAGTTGTTTTCAAACCTCGTTTTGGGCACTGTATCTGGTATTCACATCTTTACATCAACAGCTGCATTGCTTGGATCTACTATTGTGATCATACTATGCGTTGTTGCTGTTCTTGCAGTTCAGCGATTCTTCAAGGAGTACACAACTTTTGTTATGTACACTTGTGGTCTTGCTCTTGTCAACATTGTGGGCATTGCACTTATGTACAAGTGCCTTGTCTTCGCGATCTTCTATTATGCAATCTACCTTTACTTTGTCCTTACTTTCCCCTCCTTTAAGAGGAATGTGGCATTGTTTTACTTCGCTGTAGTGATCGTGCCGCACGTGAGTAACATGCAATTGCTTGCGCTCATTGTGTGTAGCATTATCTACTTTCTCTACACCTATGTTCATACTGTAGCTAAGACAGCTGGGAAATTCTCTTCCTTCTTAGACGCAGCTAAAGCTACTTTTGTCATTGACAATGAAAAGTACGTGTTGCTTAAAGACCTCGCTGGTGCTGAATTTGACCAGTATCTGGCCTCTTACAACAAGTACAAATATTTTTCTGGTACTGCTTCTGATAAGGATTATGATAAGGTCTGTATGGCATTTCTTGCCAAGGCCTTGTCATCTTTTCGTGAAGGAGGCGGTTCACAGTTGTACACACCACCTAAATTTGCAGTTGTTCAGAGTCTTAAGACCAAGCTGCAAGCAGGTATCAAAATCCTCCTGCACCCTTCAGGTGTAGTTGAGCGATGTATGGTCTCAGTTGTCTACAATGGATCTGCATTGAATGGCATCTGGCTTAAGAATGTTGTCTACTGCCCACGCCATGTAATTGGAAAATTCCGTGGTGACCAGTGGACTCACATGGTCTCAATTGCTGATTGCCGCGACTTTATAGTCAAGTGTCCAATACAGGGTATTCAGCTAAATGTCCAATCAGTTAAGATGGTAGGAGCTCTCCTCCAGTTAACTGTTCATACCAACAACACAGCCACTCCAGACTATAAGTTTGAAAGGCTCCAACCAGGATCATCGATGACAATTGCTTGTGCTTATGATGGCATTGTACGGCATGTCTATCACGTGGTCCTCCAACTTAATAATCTTATTTATGCAAGCTTCCTTAACGGAGCTTGTGGTAGTGTGGGTTACACTCTTAAGGGTAAAACACTCTACTTACATTACATGCACCACATTGAGTTTAACAACAAAACTCATAGTGGTACAGATCTTGAAGGTAACTTCTATGGCCCCTATGTGGATGAGGAAGTTATTCAGCAACAAACAGCATTCCAGTATTACACTGATAATGTTGTTGCTCAATTATATGCACACTTACTGACTGTTGATGCTAGACCAAAATGGCTGGCACAATCTCAGATAAGTATCGAGGATTTCAACTCATGGGCTGCTAACAATTCCTTTGCTAACTTCCCATGCGAACAAACTAATATGTCCTACATTATGGGACTCTCGCAAACTGCTCGAGTCCCCGTAGAACGTATCCTCAATACCATTATACAGCTAACCACCAATAGAGATGGTGCTTGTATTATGGGATCTTATGATTTCGAGTGTGATTGGACGCCAGAGATGGTATACAATCAGGCTCCAATTTCATTGCAGTCAGGAGTAGTTAAGAAAACTTGTACGTGGTTCTTCCACTTCTTGTTTATGGCTATTACCATGCTACTCGCTGCCATGCATGTTTTCCCTGTACACCTGTACCCAATAGTACTGCCATGCTTCACTGTCGTGGCATTCCTGTTGACTTTAACCATTAAACACACTGTTGTGTTTACCACTACATATTTGCTTCCGTCACTTTTGATGATGGTTGTAAATGCTAACACTTTTTGGATACCGAACACATTTCTGCGCACCTGCTACGAAACTATATTCGGTTCCCCAATTGCTCAGCGACTGTATGGTTACACTGTTGCTCTTTATATGCTGATCTATGCTGGACTTGCAATCAACTATACGTTGAAAACACTCCGGTATAGAGCAACTTCATTCTTATCTTTTTGCATGCAGTGGTTTCAATATGGTTATGTTGCACACATTGCGTACAAACTGCTTAATAAACCCTGGACAGAATCACTACTCTTCACAGCCTTCACAATGCTAACCAGTCATCCTTTGTTGGCTGCTCTTAGCTGGTGGCTAGCTGGTCGCGTAACTCTGCCCATTATCATGCCTGACTTAGCTATTCGTGTTTTGGCGTATAACGTCATTGGCTATGTCATATGTGTTCGATTTGGCCTTATGTGGCTTGCAAATCGATTCACAACTGTACCTATGGGCACATACCAGTATATGGTGTCTGTAGAGCAACTTAAGTACATGATGGCAGTTAAGATGTCCCCACCGCGTAATGCGTTTGAGGTGCTTATAGCCAACATTAGACTTCTTGGTTTGGGTGGAAACCGTAACATTGCTGTTTCTACTGTCCAAAACAAAATTCTTGATGCAAAAGCTACTGCTGTTGTTGTTGCTAACCTTCTTGAAAAGGCTGGCGTCACAAACAAGCACGCTATTTGCAAAAAGATTGTGAAACTCCACAATGATACCCTTAAAGCCACCACTTATGAGGAGGTTGAGGTAGCACTTGTGAAACTTCTTTCTCACATAATTGAGTTCTTGCCAACTGATCAGGTAGATGCTTATCTAGCTGATGCGGCCAATGCTCAACATGTTAATACCTATTTCGACAACTTGCTTGAGAACAAAGCTGTTGTTCAGGCTGTTGCCGATATCAACATTAATCTGGATTCTTATAGAATTTATAAGGAGGCAGATGCTATTTACAAACGATCTGTTGAGATGAGCGAATCTCCACAGGAGCAAAAGAAAAAGCTTAAAGCTGTTAACATTGCAAAGGCGGAATGGGAGCGTGAGGCTGCTTCTCAGCGTAAGCTTGAAAAGCTTGCTGATGCTGCTATGAAGTCTATGTATCTTGCAGAACGTGCTGAGGACCGTCGCATTAAGCTAACCTCTGGACTTACTGCAATGCTTTACCATATGCTTAGACGTCTTGACTCAGATAGGGTAAAAGCTCTGTTTGAGTGTGCTAAGGCACAAATCTTGCCAATACATGCTGTAGTTGGAATTTCTAATGACAACCTTAAAGTTATTTTTAACGATAAGGACAGCTACTCTCATTATGTAGAGGGCAACACACTTATACATAAGGGAGTTCGCTACACTATTGTGAAGAAACTCTCCTTAGATAATGCACCTATTGAAGGCGTACCAGAAGAATTCCCTGTGGTCGTTGAGACTGTTAGGGAAGGTGTGCCCCAGTTGCAAAACAATGAGCTATGTTTGCGCAATGTCTTCACTGCTCAGAACACAGCTCAGGACTTCAATGGCAATGAATCCACTGTAAAATCTTTTTATGTTACTAGAACCGGTAAGAAGATTTTGGTTGCCATTACATCAACTAAAGACAATCTTAAGACTGTGACCTGCCTTACTGAGACCGGTAAGACAGTCCTTAACTTGGACCCCCCTATGCGCTTCGCACATACCGTAGGTGGAAAACAGTCTGTTGTCTATCTCTATTTTATTCAGAATATTAGTTCACTCAACAGAGGTATGGTTATTGGCCACATCTCTGAAACTACTATCCTTCAGGCAAGTGGCACTCAAATTGAGTACCAGCAAAATGCCTCCCTTTTGACCTATTTGGCTTTCGCTGTAGACCCTAAGACAGCCTACCTTAAGCATCTTGCTGATGGTGGGTCTCCTATACAGGGTTGTATTCAGATGATTGCTACTATGGGTCCTGGATTTGCAGTTACTACTAAACCACAACCTAATGAGCATCAGTATTCTTATGGTGGTGCTTCAATTTGTCTTTATTGCCGTGCTCATATACCACATCCTGGTGTTGATGGACGGTGCCCCTACAAAGGCCGCTTTGTTCACATCGACAAAGATAAGGAACCTGTTTCCTTCGCCTTGATTCATGAGCCATGCAGTTCTTGTCAACGGTGGGTCAATTATGACTGCACCTGTGGATCTAGTCTGCAGAATTCGGCTTATTTAAACGAGTAA
Protein
MAKNKSKRDAIALPENVPPPLQLFIHVAAAEEGHSKVTTYLGNYNLYATKAPPGVQVLSAKTSLTDFENVFGAQPTLRSIRNLVCEARSAEWTTSKNAFALKATQLDYSDAVLRAMIRFCPPKVSTLAAFALFGRLVKIEDKELAELARDTALELAYTAKIGTSLADTRSVSLIHKDAYLTLSNEVVGVTFTAALMAKATTVNGAMQYSNFYLYPRATIKVTDGKAEAIATKPLPAATKGKPITEDVNLLPDYQQLLVDQVTGTEVKVGALTYVKTTDTPPLYFPKVKGGVIGIALKQQGTAAKKLNVVFHAQPDDVLLAFIQLQQFLNRTSDSSVEITDCQSYEVSPTVTVKIGPSKPGDVIVATDEEYLKCFETPEVGRLYKVFQTQSWAIIERAFSSMKIRVSKALSAFISFLQNLADNFTAISGVVTALIRELQDLTLDVATRITNIQFVYRAGKLIVDTTSVIAKLFQPFCDFISPFLRKVAGFAIYTVGNRMLMFTSTGTFLLTKATTKILNKAKYIFDVEPEYPVDVTTSKVVVHEALQQIDTKPTRALEAVDVVVGNTVLQMATDGTAFYPSDGTHASLPGFKAGSDELFISFNCDLFDDETNAQINETLAAYELNQLVAPGDSTPRQIATLVVDTLADAITDHFPEKTIDLPEDYQVFSDHDDLPLAQYHIPDHLSLYIQAMEGEDDSGDEICIEDDDYDCPQADEDTEGVIPQQWELPDVDKFLLKIQERKTSSDEVLSVDVYPKPEPVGNVGIDDSASEKKPNGDPVPDPEVHPTLESVDVERPIETANQAVEYKPSDTTFVVDEEQLQESTPEHELRSYEGEFDSDDEIIIPIVPVTPADLKPQTITIKEYFKSEKLETINEGSTESVTQSDDSFDESFVDAESDDPQDPAVYDDTTIITDSTDVGDEPETTLATIVNTPLTLDNNLPPEAIKQPSPTKVELVVGELASIKFDNSVLVNPANAQLTNGGGAARAIAKLAGPKYQEYCNSVAPISGPLTTDSFDAKKLGVACILHVVPPKGSDPNVQELLYQAYKSILTEPAHYVIPILGAGIFGCNPVHSLDAFRKACPSDIGRVTLVTMNKNHLQVWDALNRTIVRTTTDYDQVTTKALTPQGVLEANLFDGEDFVQEPKPGQIYLEVTEEVQNQAKELDLNLQQYCVYLKTCHHKWVVSRMNGLMHLKQKDNNCFVSAGVNLFQNTAYQLRPAIDALYREYLNGNPNRFVAWIYASTNRRVGEMGCPQQVISLLVSNSDAAFSATTACCNTYFNHTGVISVAREYDPIQPKVYCMKCDVWTPFTPQSGKGAVAIGTSADEPTGPAIKFAAAHCWYTNGKKTVNGYDTKANVVATYHRFDVPKPQLVEDVVALPTKNDFEVLNVEELPQDSVLHLDPPPVQALQPKANQHIEILENPDYLDILDLWIRKPKFILVKSWSVLGRALCKAGKVVFVSASLLTRFYNYLVEIGALDSTIRLSVDLTCKFVRTVLPSSNTVHKTCLGLYYSAQTLFVSLAPFLMLPAVVSLLNSGYTIGTYLYAKTGWPCNYNATQHFDYNSYCAGDLVCQACFDGQDSLHLYPHLRVNQQPLQTTDYTVYALSLILLLANMTLVMGTLIVTFFVNFYGVQIPFYGTLLIDYQSALMMTFSVYYFYKVMKFFRHLTHGCKIPTCMVCAKLRTPPTITVETVVQGRKYPSVIETNGGFTICKEHNFYCKDCSLQTPGTFIPTEAIESLSRATRLSVKPTAPAFLLARDVECQTDVVVARAMHNQNAHVCISKYSDIRTVDQLLKPTPLFSYTPDVIIAADFDNRGSLKTAKELAVVLSMDLKRTIIIIDQAYSRPIDNYQEVASRIEKYYPVAKITPTGDIFTDIKQATNGQASDSAINAAVLAVQRGLDFTIDNPNNILPHYAFDFSTLNAEDQSTILESGCAKGNLKGTNVGVVLSASLVTRLSQQAIRVIANAASRNGVTCAVTPSTLVMRGNIATQPLTRIKAGAPPMRQKILCVILALAIVYFAAMAFGFLASQITLNTVPTIKSDIRASTFYVVRDGVLDTVRSNDKCFANKFLAFDSFIQAPYTNSPDCPVVVGVVEVTTHSIPGIPAGVIHRDGLILNIYEQSLYETHQRQSMVRDALSLKTANLFNLGKRVVVGYTQHEVVVGTSYFNSPALFNAKCTFLQYQDTRQLYCYDTVPTEHKLYSDVLPHVEYKAIDINGDLVPFKIPEQIMFYPHIVRYTSNSYCRMGHCFNTNPGICISFTDEFPYSENVKPGVYCADTSLQLFSNLVLGTVSGIHIFTSTAALLGSTIVIILCVVAVLAVQRFFKEYTTFVMYTCGLALVNIVGIALMYKCLVFAIFYYAIYLYFVLTFPSFKRNVALFYFAVVIVPHVSNMQLLALIVCSIIYFLYTYVHTVAKTAGKFSSFLDAAKATFVIDNEKYVLLKDLAGAEFDQYLASYNKYKYFSGTASDKDYDKVCMAFLAKALSSFREGGGSQLYTPPKFAVVQSLKTKLQAGIKILLHPSGVVERCMVSVVYNGSALNGIWLKNVVYCPRHVIGKFRGDQWTHMVSIADCRDFIVKCPIQGIQLNVQSVKMVGALLQLTVHTNNTATPDYKFERLQPGSSMTIACAYDGIVRHVYHVVLQLNNLIYASFLNGACGSVGYTLKGKTLYLHYMHHIEFNNKTHSGTDLEGNFYGPYVDEEVIQQQTAFQYYTDNVVAQLYAHLLTVDARPKWLAQSQISIEDFNSWAANNSFANFPCEQTNMSYIMGLSQTARVPVERILNTIIQLTTNRDGACIMGSYDFECDWTPEMVYNQAPISLQSGVVKKTCTWFFHFLFMAITMLLAAMHVFPVHLYPIVLPCFTVVAFLLTLTIKHTVVFTTTYLLPSLLMMVVNANTFWIPNTFLRTCYETIFGSPIAQRLYGYTVALYMLIYAGLAINYTLKTLRYRATSFLSFCMQWFQYGYVAHIAYKLLNKPWTESLLFTAFTMLTSHPLLAALSWWLAGRVTLPIIMPDLAIRVLAYNVIGYVICVRFGLMWLANRFTTVPMGTYQYMVSVEQLKYMMAVKMSPPRNAFEVLIANIRLLGLGGNRNIAVSTVQNKILDAKATAVVVANLLEKAGVTNKHAICKKIVKLHNDTLKATTYEEVEVALVKLLSHIIEFLPTDQVDAYLADAANAQHVNTYFDNLLENKAVVQAVADININLDSYRIYKEADAIYKRSVEMSESPQEQKKKLKAVNIAKAEWEREAASQRKLEKLADAAMKSMYLAERAEDRRIKLTSGLTAMLYHMLRRLDSDRVKALFECAKAQILPIHAVVGISNDNLKVIFNDKDSYSHYVEGNTLIHKGVRYTIVKKLSLDNAPIEGVPEEFPVVVETVREGVPQLQNNELCLRNVFTAQNTAQDFNGNESTVKSFYVTRTGKKILVAITSTKDNLKTVTCLTETGKTVLNLDPPMRFAHTVGGKQSVVYLYFIQNISSLNRGMVIGHISETTILQASGTQIEYQQNASLLTYLAFAVDPKTAYLKHLADGGSPIQGCIQMIATMGPGFAVTTKPQPNEHQYSYGGASICLYCRAHIPHPGVDGRCPYKGRFVHIDKDKEPVSFALIHEPCSSCQRWVNYDCTCGSSLQNSAYLNE
Summary
Catalytic Activity
ATP + H2O = ADP + H(+) + phosphate
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)
Similarity
Belongs to the coronaviruses polyprotein 1ab family.
Uniprot
Pubmed
EMBL
Proteomes
Pfam
Interpro
IPR032505
Corona_NSP4_C
IPR009469 RNA_pol_N_coronovir
IPR008740 Peptidase_C30
IPR027352 CV_ZBD
IPR001205 RNA-dir_pol_C
IPR036333 NSP10_sf
IPR037227 EndoU-like
IPR014822 NSP9
IPR009003 Peptidase_S1_PA
IPR027417 P-loop_NTPase
IPR037230 NSP8_sf
IPR038123 NSP4_C_sf
IPR029063 SAM-dependent_MTases
IPR018995 RNA_synth_NSP10_coronavirus
IPR009466 NSP11
IPR014829 NSP8
IPR014827 Viral_protease
IPR042515 Nsp15_N
IPR009461 Coronavirus_NSP16
IPR002589 Macro_dom
IPR027351 (+)RNA_virus_helicase_core_dom
IPR007094 RNA-dir_pol_PSvirus
IPR036499 NSP9_sf
IPR009469 RNA_pol_N_coronovir
IPR008740 Peptidase_C30
IPR027352 CV_ZBD
IPR001205 RNA-dir_pol_C
IPR036333 NSP10_sf
IPR037227 EndoU-like
IPR014822 NSP9
IPR009003 Peptidase_S1_PA
IPR027417 P-loop_NTPase
IPR037230 NSP8_sf
IPR038123 NSP4_C_sf
IPR029063 SAM-dependent_MTases
IPR018995 RNA_synth_NSP10_coronavirus
IPR009466 NSP11
IPR014829 NSP8
IPR014827 Viral_protease
IPR042515 Nsp15_N
IPR009461 Coronavirus_NSP16
IPR002589 Macro_dom
IPR027351 (+)RNA_virus_helicase_core_dom
IPR007094 RNA-dir_pol_PSvirus
IPR036499 NSP9_sf
SUPFAM
Gene 3D
ProteinModelPortal
PDB
2Q6F
E-value=2e-71 Score= 242 Identity=44.44%
Cov(Q)=8.44% Cov(P)=99.03%
3D Structure
Ontologies
GO
GO:0039694 P:viral RNA genome replication
GO:0033644 C:host cell membrane
GO:0044165 C:host cell endoplasmic reticulum
GO:0005524 F:ATP binding
GO:0019082 P:viral protein processing
GO:0008270 F:zinc ion binding
GO:0016896 F:exoribonuclease activity, producing 5'-phosphomonoesters
GO:0016021 C:integral component of membrane
GO:0004197 F:cysteine-type endopeptidase activity
GO:0003724 F:RNA helicase activity
GO:0039520 P:induction by virus of host autophagy
GO:0008168 F:methyltransferase activity
GO:0003968 F:RNA-directed 5'-3' RNA polymerase activity
GO:0032259 P:methylation
GO:0006351 P:transcription, DNA-templated
GO:0003723 F:RNA binding
GO:0044220 C:host cell perinuclear region of cytoplasm
GO:0008242 F:omega peptidase activity
GO:0033644 C:host cell membrane
GO:0044165 C:host cell endoplasmic reticulum
GO:0005524 F:ATP binding
GO:0019082 P:viral protein processing
GO:0008270 F:zinc ion binding
GO:0016896 F:exoribonuclease activity, producing 5'-phosphomonoesters
GO:0016021 C:integral component of membrane
GO:0004197 F:cysteine-type endopeptidase activity
GO:0003724 F:RNA helicase activity
GO:0039520 P:induction by virus of host autophagy
GO:0008168 F:methyltransferase activity
GO:0003968 F:RNA-directed 5'-3' RNA polymerase activity
GO:0032259 P:methylation
GO:0006351 P:transcription, DNA-templated
GO:0003723 F:RNA binding
GO:0044220 C:host cell perinuclear region of cytoplasm
GO:0008242 F:omega peptidase activity
Subcellular Location
From MSLVP
Capsid
From Uniprot
Host cytoplasm
Host perinuclear region
Host endoplasmic reticulum
Host membrane
Host perinuclear region
Host endoplasmic reticulum
Host membrane
Topology
Length:
3626
Number of predicted TMHs:
14
Exp number of AAs in TMHs:
326.251789999999
Exp number, first 60 AAs:
0.00569
Total prob of N-in:
0.07414
outside
1 - 1512
TMhelix
1513 - 1535
inside
1536 - 1600
TMhelix
1601 - 1623
outside
1624 - 1632
TMhelix
1633 - 1655
inside
1656 - 2003
TMhelix
2004 - 2026
outside
2027 - 2292
TMhelix
2293 - 2315
inside
2316 - 2335
TMhelix
2336 - 2358
outside
2359 - 2372
TMhelix
2373 - 2404
inside
2405 - 2824
TMhelix
2825 - 2844
outside
2845 - 2847
TMhelix
2848 - 2865
inside
2866 - 2871
TMhelix
2872 - 2894
outside
2895 - 2913
TMhelix
2914 - 2936
inside
2937 - 2942
TMhelix
2943 - 2960
outside
2961 - 2974
TMhelix
2975 - 2997
inside
2998 - 3008
TMhelix
3009 - 3031
outside
3032 - 3626
