Coronavirus Database

Strain

Goat_NC_034976 (Region: China; Strain: Goat torovirus strain SZ, complete genome.; Date: 29-Sep-12)

Gene

membrane glycoprotein

Description

Annotated in NCBI, membrane glycoprotein

Location

NC_034976(+):25772-26473

GenBank Accession

YP_009380538.1

Full name

Membrane protein

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGTTTGATACCAATTATTGGCCCTTCCCTGACCAGGCTCCAAACCCATTTAATGCTCAAGTTGAGCAGTTATCAGCAACTGAAAATGTTTATATTTTTCTTACTACACTTTTTGGAATACTCCAACTAGTGTATGTAATGTTTAAGTTGCTATGTACTATGTTTCCAGCTTTGCATTGGTCGCCTATATGGCGCGGTTTGGAGAATTTTTGGCTTTTCTTGAGTCTTGCATCCCTTGCAATTGCCTATTGGTGGCTTCCCAGTATGACTTTTACTGGCTATTGGGCATTGACTATTATTGCCACCATTTTGGTTTTGATTATGTTGATAATGATGTTTATTAAGTTTGTTAGTTTTGTTAGTTTGTTTTATAGGACTGGTAGTTTTGCAATTGCTATACGGGGACCAATTGTGCTTGTTGCACTTGATGTTACCATAAAGCTTCACTGTACACCTTTTGCAATTCTTGTTAAGGAGGTTGGCAATATCTTTTATTTATCAGAATATTGCAATAAACCATTAACGGCTGCTCAGGTTGCCGCATTGCGGATTTGTGTTGGTGGACAGTGGTTTGCTTATACGCGGTCCACTACTACCAGCGCCGCTAAAGTAGCTGCAGCTAACAGCACTGCAAAGTATCATCTTTTTATTTTGCAAGGTGTTGCAGATTACACACAATTGTCTAGTGTTAAGTTTGAGTAG

Protein

MFDTNYWPFPDQAPNPFNAQVEQLSATENVYIFLTTLFGILQLVYVMFKLLCTMFPALHWSPIWRGLENFWLFLSLASLAIAYWWLPSMTFTGYWALTIIATILVLIMLIMMFIKFVSFVSLFYRTGSFAIAIRGPIVLVALDVTIKLHCTPFAILVKEVGNIFYLSEYCNKPLTAAQVAALRICVGGQWFAYTRSTTTSAAKVAAANSTAKYHLFILQGVADYTQLSSVKFE

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Interacts with many viral proteins in infected cells. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in the viral mRNA packaging into the virus (By similarity).
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus (By similarity).

Similarity

Belongs to the torovirinae M protein family.

Keywords

Host Golgi apparatus Host membrane Membrane Reference proteome Transmembrane Transmembrane helix Viral envelope protein Viral matrix protein Virion

Feature

chain Membrane protein

Uniprot

A0A1X9H814 A0A481W694 Q70KN2 O90305 A0A3G4S8J8 A0A3G4S8L7 + More
A0A0U5AKT7 A0A3G1RGD1 P27904 D2K6C8 A0A097P9L3 D2K6D8 A0A513Q9X6 A0A513QA15 A0A060L1F8 D2K6D4 Q70KN6 A0A481ZJZ2 Q70KN9 A7BI34 D2K6D5 A0A239QPW0 U5IJ81 C1J1E2 Q70KN7 A0A513QA03 V5J424

Pubmed

12915570 9879765 16137782 26708248 2024492 20558206 + More
24903213 17567770 24122107

EMBL

KR527150 ANA57417.1 MK521914 QBJ04616.1 AJ575374 AJ575375 + More
AJ575376 AJ575377 CAE01340.1 CAE01341.1 CAE01342.1 CAE01343.1 AF076621 AY427798 MG957145 AYU75158.1 MG957146 AYU75162.1 LC088094 LC088095 BAU21407.1 BAU21413.1 MG996765 AWV66920.1 X52505 GU181240 GU181241 GU181242 GU181243 GU181244 ACZ71735.1 ACZ71736.1 ACZ71737.1 ACZ71738.1 ACZ71739.1 KM403390 AIU41586.1 GU181250 MK379077 MK379137 MK379161 ACZ71745.1 QBJ02014.1 QBJ02092.1 QBJ02120.1 MK379100 QBJ02042.1 MK379131 QBJ02083.1 KF727566 KF727567 KF727568 KF727569 KF727570 KF727571 KF727572 KF727573 KF727574 KF727575 KF727576 KF727577 KF727578 KF727579 KF727580 KF727583 KF727584 HG764752 HG764753 HG764754 HG764755 HG764756 HG764757 HG764758 HG764759 HG764760 HG764761 HG764762 HG764763 HG764764 HG764765 HG764766 HG764769 HG764770 AIC65772.1 AIC65773.1 AIC65774.1 AIC65775.1 AIC65776.1 AIC65777.1 AIC65778.1 AIC65779.1 AIC65780.1 AIC65781.1 AIC65782.1 AIC65783.1 AIC65784.1 AIC65785.1 AIC65786.1 AIC65789.1 AIC65790.1 CDJ80020.1 CDJ80021.1 CDJ80022.1 CDJ80023.1 CDJ80024.1 CDJ80025.1 CDJ80026.1 CDJ80027.1 CDJ80028.1 CDJ80029.1 CDJ80030.1 CDJ80031.1 CDJ80032.1 CDJ80033.1 CDJ80034.1 CDJ80037.1 CDJ80038.1 GU181246 GU181248 KF727581 KF727582 HG764767 HG764768 ACZ71741.1 ACZ71743.1 AIC65787.1 AIC65788.1 CDJ80035.1 CDJ80036.1 GU181245 AJ575369 AJ575371 ACZ71740.1 CAE01335.1 CAE01337.1 MH603532 QBK95469.1 AJ575368 CAE01334.1 AB285126 BAF75424.1 GU181247 GU181249 MK379062 MK379166 ACZ71742.1 ACZ71744.1 QBJ01994.1 QBJ02128.1 LT900503 SNT95685.1 JQ860350 AGB05583.1 FJ232069 ACO48289.1 AJ575370 CAE01336.1 MK379125 QBJ02074.1 JQ740196 AFZ75472.1

Proteomes

UP000207672 UP000000355 UP000102793 UP000138412 UP000006571 UP000119381 + More
UP000269215 UP000111898

Pfam

PF10943 DUF2632

Interpro

IPR024251 M_Torovirus

ProteinModelPortal

A0A1X9H814 A0A481W694 Q70KN2 O90305 A0A3G4S8J8 A0A3G4S8L7 + More
A0A0U5AKT7 A0A3G1RGD1 P27904 D2K6C8 A0A097P9L3 D2K6D8 A0A513Q9X6 A0A513QA15 A0A060L1F8 D2K6D4 Q70KN6 A0A481ZJZ2 Q70KN9 A7BI34 D2K6D5 A0A239QPW0 U5IJ81 C1J1E2 Q70KN7 A0A513QA03 V5J424

KEGG

vg:3707769 vg:17603138

GO

GO:0016021  C:integral component of membrane
GO:0044178  C:host cell Golgi membrane
GO:0055036  C:virion membrane
GO:0039660  F:structural constituent of virion
GO:0019031  C:viral envelope

From MSLVP

Host nucleus. Host cytoplasm.

From Uniprot

Virion membrane
Host Golgi apparatus membrane

Length:

233

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

81.8668000000001

Exp number, first 60 AAs:

21.83725

Total prob of N-in:

0.08015

POSSIBLE N-term signal

sequence

outside

1 - 29

TMhelix

30 - 52

inside

53 - 64

TMhelix

65 - 87

outside

88 - 96

TMhelix

97 - 119

inside

120 - 233

Sequence

Summary

Ontologies

Subcellular Location

Topology