CoVDB Coronavirus Database (v3)   
Strain
Bat_NC_048212 (Region: Cameroon;  Strain: Bat coronavirus;  Date: Dec-13)
Gene
Membrane protein
Description
Annotated in NCBI,  Membrane protein
Location
NC_048212(+):25568-26233
GenBank Accession
YP_009824992.1
Full name
Membrane protein      
Alternative Name
E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein
 

Sequence

CDS
ATGTCCTCGAGTAATTCGACCTTCTCTAAGGAGGAGGTTTTTAAAGCCGTCAAGGATTGGAATTTTGCAGTTGCAATCCTTTTACTTTTCGTGACCATATTGCTGCAGTGGGGTTACCCTTCTCGCGTTAAGGCGATATGGGTCGTGAAAATGTTCATCTTGTGGTTGCTGTGGCCAGTGTCCATAGCTGCCTCAGTCTTTGCCGCTGTCTACCCTATTAATAAGGTAGCCTTCGGCTTTGCTATAGCTTTTGCTTGCATTACTGCGCTTATGTGGCTCAGTTATTTTGTAAGCTCGCTCAGATTACTTTGCAGAACTGGTTCCTGGTGGGCATTTATGCCCGAGACCAATATGCTGCTTAATGTGCCTTTCATCGGGCGCACAGTAACCAGACCAATCTTGAATGACTCCGCTGCTTTGCAGTTTTTCATTCTCAGAGGCCAGGTTCAATTTGAAGGATTTGTGCTGGGGAAATGTGCCCCAACAGAAATGCCCGAAGTCGTCACAGTTGCCAAGGCAGGGTCCTTGGTATGGTACAAGAAGGCTCTCACGCGAACTGTGGGCCCGAAGTCAGGTGTGGTTGTCTACATAAAATTTAAAGTAGGCAATCACAGAGTGCAAAATGCAAATGATGATGACGGACAATTGGCCATGTTTTTGGCTTAA
Protein
MSSSNSTFSKEEVFKAVKDWNFAVAILLLFVTILLQWGYPSRVKAIWVVKMFILWLLWPVSIAASVFAAVYPINKVAFGFAIAFACITALMWLSYFVSSLRLLCRTGSWWAFMPETNMLLNVPFIGRTVTRPILNDSAALQFFILRGQVQFEGFVLGKCAPTEMPEVVTVAKAGSLVWYKKALTRTVGPKSGVVVYIKFKVGNHRVQNANDDDGQLAMFLA

Summary

Function
Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.
Subunit
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Similarity
Belongs to the betacoronaviruses M protein family.
Uniprot
Q66VB9  
EMBL
AY702026    AAU07933.1   
Pfam
PF01635   Corona_M
Interpro
IPR002574   Corona_M
ProteinModelPortal
Q66VB9  

Ontologies

GO
GO:0019058  P:viral life cycle
 GO:0039660  F:structural constituent of virion
 GO:0044178  C:host cell Golgi membrane
 GO:0030683  P:evasion or tolerance by virus of host immune response
 GO:0019031  C:viral envelope
 GO:0016021  C:integral component of membrane
 GO:0055036  C:virion membrane

Subcellular Location

From MSLVP

Topology

Length:
221
Number of predicted TMHs:
3
Exp number of AAs in TMHs:
64.29514
Exp number, first 60 AAs:
30.09861
Total prob of N-in:
0.23181
POSSIBLE N-term signal
sequence
outside
1  -  19
TMhelix
20  -  39
inside
40  -  51
TMhelix
52  -  71
outside
72  -  75
TMhelix
76  -  98
inside
99  -  221
 
 
Copyright@ 2018-2023    Any Comments and suggestions mail to:  zhuzl@cqu.edu.cn, mg@cau.edu.cn   渝ICP备19006517号

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