Strain

CANADA_HS_2003_NC_004718 (Region: Canada: Toronto;  Strain: SARS coronavirus, complete genome.;  Date: 2003)

Gene

hypothetical protein sars7a

Description

Annotated in NCBI,  hypothetical protein sars7a

Location

NC_004718(+):27273-27641

GenBank Accession

NP_828857.1

Full name

SARS_X4 domain-containing protein       + More
Protein 7a      

Alternative Name

Accessory protein 7a
Protein U122
Protein X4

CDS

ATGAAAATTATTCTCTTCCTGACATTGATTGTATTTACATCTTGCGAGCTATATCACTATCAGGAGTGTGTTAGAGGTACGACTGTACTACTAAAAGAACCTTGCCCATCAGGAACATACGAGGGCAATTCACCATTTCACCCTCTTGCTGACAATAAATTTGCACTAACTTGCACTAGCACACACTTTGCTTTTGCTTGTGCTGACGGTACTCGACATACCTATCAGCTGCGTGCAAGATCAGTTTCACCAAAACTTTTCATCAGACAAGAGGAGGTTCAACAAGAGCTCTACTCGCCACTTTTTCTCATTGTTGCTGCTCTAGTATTTTTAATACTTTGCTTCACCATTAAGAGAAAGACAGAATGA

Protein

MKIILFLTLIVFTSCELYHYQECVRGTTVLLKEPCPSGTYEGNSPFHPLADNKFALTCTSTHFAFACADGTRHTYQLRARSVSPKLFIRQEEVQQELYSPLFLIVAALVFLILCFTIKRKTE

Function

Non-structural protein which is dispensable for virus replication in cell culture.

Subunit

Interacts with the spike glycoprotein, M protein, E protein and the accessory protein 3a. Interacts with human SGT.
Interacts with the spike glycoprotein, M protein, E protein and the accessory protein 3.

Miscellaneous

Bat coronavirus rp3 is highly similar to SARS-CoV (SARS-like).
Bat coronavirus HKU3 is highly similar to SARS-CoV (SARS-like).
Bat coronavirus 279/2005 is highly similar to SARS-CoV (SARS-like).

Keywords

3D-structure   Host endoplasmic reticulum   Host Golgi apparatus   Host membrane   Host-virus interaction   Membrane   Modulation of host cell cycle by virus   Reference proteome   Signal   Transmembrane   Transmembrane helix   Virion  

Feature

chain  Protein 7a

Uniprot

D2E2E4   Q6RD14   Q6SRQ5   Q692D8   Q6RD58   Q6T1D6   + More
Q6VA94   Q6SRX0   Q6VA72   Q6SRT0   Q6RCY1   C4P6R3   Q1EFN9   Q6RD25   Q6RD03   Q6SRT5   Q1EFM6   Q6SRV5   Q3ZTB9   Q6RCX0   Q4JDP8   Q4JDR1   Q3S2B9   Q6SRV0   Q3ZTD4   Q6SRW5   Q6RD36   Q6SRW0   Q6SRS5   Q6R7Y0   Q6VA83   Q6SRY5   Q6SRU0   Q6SRR5   Q5Y181   Q6SRR0   Q6SRY0   Q6S8D1   Q6SRS0   Q6RCV9   Q6RCZ2   Q3ZTE7   Q6SRX5   Q6SRZ0   Q6RD47   Q76XZ9   Q6SRU5   Q19QW4   Q6SZ88   D2E1F3   D2E227   D2E1D8   D2E271   D3KDN1   P59635   A7J8M0   D2E2I7   Q6GYQ5   J9TEN5   J9T5H6   J9SF21   A0A0K1Z075   A0A0K1Z059   A0A1W6S796   D2DJX0   U5WI44   U5WIM6   A0A2D1PX67   A0A2D1PXH7   A0A2D1PXE3   Q3I5J0   D5HJV0   D5HJT9   A0A023PUX1   A0A2D1PXB5   D5HJS8   D5HJW3   D5HJR7   D5HJX4   D5HJQ6   D5HJY5   Q3LZU5   D5HK07   Q3LZX7   A0A2D1PXB6   A0A0U2ND36   U5WI16   A0A0U1UZF3   Q3LZU8   A0A0U1UZE6   A0A0U1UZE3   A0A0U1UZD9   A0A0U1UZE9   Q0QDX4   Q0Q470   Q0QDY4   Q0Q479   A0A166ZLD3   A0A221ZS13   D5HJZ6  

Pubmed

14569023    20463816    14983045    15809907    15757562    14709660    + More
14654320    16625834    16485471    16140765    14527350    14733771    16112670    17222058    30393776    22412934    12730500    12730501    12853594    12876307    15642263    15194747    15220404    15564512    16840309    17037516    16580632    16328780    19370068    20016037    24172901    29190287    16195424    20071579    24719429    16169905    26719272    16840328    26847648   

EMBL

FJ882950    ACZ72114.1    AY502927    AAR87553.1    AY451873    AAS44684.1    + More
AY654624    AAT76154.1    AY502923    AAR87509.1    AH013657    AAS01070.1    AY345986    AAP94743.1    AY451860    AAS44619.1    AY345988    AAP94765.1    AY451868    AAS44659.1    AY502930    AAR87586.1    FJ882963    ACQ82731.1    AY864805    AAY60786.1    AY502926    AAR87542.1    AY502928    AAR87564.1    AY451867    AAS44654.1    AY864806    AAY60799.1    AY451863    AAS44634.1    AY572038    AAU04670.1    AY502931    AAR87597.1    AY686864    AAV49736.1    AY686863    AAV91637.1    DQ182595    ABA02273.1    AY451864    AAS44639.1    AY572035    AAU04655.1    AY451861    AAS44624.1    AY502925    AAR87531.1    AY451862    AAS44629.1    AY451869    AAS44664.1    AY508724    AAR91592.1    AY345987    AAP94754.1    AY451857    AAS44604.1    AY451866    AAS44649.1    AY451871    AAS44674.1    AY714217    AAU81615.1    AY451872    AAS44679.1    AY451858    AAS44609.1    AY463060    AAR86781.1    AY451870    AAS44669.1    AY502932    AAR87608.1    AY502929    AAR87575.1    AY572034    AAU04640.1    AY451859    AAS44614.1    AY451856    AAS44599.1    AY502924    AAR87520.1    AY290752    AAR27474.1    AY451865    AAS44644.1    DQ497008    JX163924    JX163926    JX163928    ABF65842.1    AFR58692.1    AFR58720.1    AFR58748.1    AY444813    MK062179    MK062180    MK062181    MK062182    MK062183    MK062184    AAR27055.1    AYV99753.1    FJ882927    FJ882932    FJ882933    FJ882934    FJ882935    FJ882936    FJ882937    FJ882938    FJ882939    FJ882946    FJ882947    FJ882949    JF292921    KF514388    KF514392    KF514394    KF514396    KF514397    KF514398    KF514399    KF514400    KF514404    KF514408    KF514409    KF514413    KF514415    KF514418    KF514419    KF514421    KF514422    KF514423    ACZ71773.1    ACZ71847.1    AEA11004.1    AGT20799.1    AGT20859.1    AGT20889.1    AGT20919.1    AGT20934.1    AGT20949.1    AGT20964.1    AGT20979.1    AGT21039.1    AGT21099.1    AGT21114.1    AGT21174.1    AGT21204.1    AGT21249.1    AGT21264.1    AGT21294.1    AGT21309.1    AGT21324.1    FJ882942    FJ882943    FJ882951    FJ882959    FJ882962    HQ890526    HQ890527    HQ890528    HQ890529    HQ890530    HQ890531    HQ890532    HQ890533    HQ890534    HQ890535    HQ890536    HQ890537    HQ890538    HQ890539    HQ890540    JF292902    JF292903    JF292904    JF292905    JF292906    ACZ71997.1    AEA10404.1    FJ882926    FJ882928    FJ882929    FJ882930    FJ882931    FJ882940    FJ882941    FJ882944    FJ882954    FJ882955    FJ882956    FJ882960    JF292922    JX162087    KF514389    KF514390    KF514391    KF514393    KF514395    KF514401    KF514402    KF514403    KF514405    KF514406    KF514407    KF514410    KF514411    KF514412    KF514414    KF514416    KF514417    KF514420    ACZ71758.1    ACZ71802.1    ACZ71967.1    AEA11019.1    AFM43873.1    AGT20814.1    AGT20829.1    AGT20844.1    AGT20874.1    AGT20904.1    AGT20994.1    AGT21009.1    AGT21024.1    AGT21054.1    AGT21069.1    AGT21084.1    AGT21129.1    AGT21144.1    AGT21159.1    AGT21189.1    AGT21219.1    AGT21234.1    AGT21279.1    FJ882945    FJ882948    FJ882952    FJ882957    FJ882958    FJ882961    HQ890541    HQ890542    HQ890543    HQ890544    HQ890545    HQ890546    JF292907    JF292908    JF292909    JF292910    JF292911    JF292912    JF292913    JF292914    JF292915    JF292916    JF292917    JF292918    JF292919    JF292920    ACZ72041.1    AEA10629.1    GU553363    GU553364    GU553365    JQ316196    JN854286    ADC35489.1    AFD56979.1    AFK10260.1    AY278741    AY274119    AY282752    AY278554    AY278491    AY278487    AY278488    AY278489    AY278490    AY279354    AY291451    AY310120    AY291315    AY338174    AY338175    AY348314    AP006557    AP006558    AP006559    AP006560    AP006561    AY323977    AY427439    AY463059    AY322208    DQ898174    ABI96964.1    FJ882953    ACZ72157.1    AY595412    AAT52336.1    JX163927    AFR58734.1    JX163925    AFR58706.1    JX163923    AFR58678.1    KP886808    AKZ19081.1    KP886809    AKZ19092.1    KU973692    ARO76387.1    FJ588686    ACU31037.1    KC881006    AGZ48824.1    KC881005    AGZ48812.1    KY417142    KY417143    KY417144    KY417145    KY417146    KY417147    KY417149    ATO98114.1    ATO98126.1    ATO98138.1    ATO98151.1    ATO98163.1    ATO98175.1    ATO98199.1    KY417152    ATO98237.1    KY417148    ATO98187.1    DQ071615    GQ153543    ADE34771.1    GQ153542    ADE34760.1    KF569996    AHX37563.1    KY417151    ATO98225.1    GQ153541    ADE34749.1    GQ153544    ADE34784.1    GQ153540    ADE34738.1    GQ153545    ADE34795.1    GQ153539    ADE34727.1    GQ153546    ADE34806.1    DQ084200    AAZ41345.1    GQ153548    ADE34828.1    DQ022305    KY417150    ATO98212.1    KT444582    ALK02464.1    KF367457    AGZ48838.1    KJ473816    AIA62335.1    DQ084199    AAZ41334.1    KJ473814    AIA62315.1    KJ473813    AIA62305.1    KJ473812    AIA62295.1    KJ473815    AIA62325.1    DQ412043    ABD75328.1    DQ648857    DQ412042    ABD75319.1    DQ648856    ABG47065.1    KU182964    ANA96033.1    KY938558    ASO66814.1    GQ153547    ADE34817.1   

Proteomes

UP000180371    UP000174857    UP000101079    UP000148533    UP000133546    UP000115935    + More
UP000125082    UP000112237    UP000133349    UP000148329    UP000124386    UP000149347    UP000153024    UP000132037    UP000126514    UP000115496    UP000163176    UP000141980    UP000139901    UP000117876    UP000129608    UP000171372    UP000133987    UP000110133    UP000099158    UP000127950    UP000166558    UP000116351    UP000135071    UP000180361    UP000180362    UP000097931    UP000121467    UP000125925    UP000128288    UP000150617    UP000151673    UP000151756    UP000153830    UP000155701    UP000157930    UP000160899    UP000161442    UP000161729    UP000162782    UP000164349    UP000169779    UP000173963    UP000174280    UP000180434    UP000180435    UP000180436    UP000180437    UP000180438    UP000180439    UP000180440    UP000180441    UP000180442    UP000180443    UP000180444    UP000180445    UP000180446    UP000120111    UP000180409    UP000180410    UP000180411    UP000180413    UP000180414    UP000180415    UP000180416    UP000180417    UP000180418    UP000180419    UP000180420    UP000180421    UP000180422    UP000180423    UP000180424    UP000180425    UP000180426    UP000180427    UP000180428    UP000180429    UP000180430    UP000180431    UP000180432    UP000180433    UP000097852    UP000106870    UP000114004    UP000117796    UP000119316    UP000119820    UP000124542    UP000125968    UP000130610    UP000133348    UP000141212    UP000143912    UP000145152    UP000149516    UP000159535    UP000166143    UP000171773    UP000180363    UP000180364    UP000180365    UP000180366    UP000180367    UP000180368    UP000180369    UP000180370    UP000180372    UP000180373    UP000180374    UP000180375    UP000180376    UP000180377    UP000180378    UP000145008    UP000180383    UP000180384    UP000180385    UP000180386    UP000180387    UP000180388    UP000180389    UP000180390    UP000180391    UP000180393    UP000180394    UP000180395    UP000180396    UP000180397    UP000180398    UP000180399    UP000180400    UP000180401    UP000180402    UP000180403    UP000180404    UP000180405    UP000180406    UP000180407    UP000180408    UP000112510    UP000152329    UP000180379    UP000180381    UP000180382    UP000000354    UP000103670    UP000109640    UP000116947    UP000121636    UP000131569    UP000131955    UP000137377    UP000138690    UP000143093    UP000145651    UP000146108    UP000146181    UP000146296    UP000148194    UP000153467    UP000160648    UP000164441    UP000172416    UP000166757    UP000180412    UP000158790    UP000180360    UP000148108    UP000105036    UP000174731    UP000143681    UP000122532    UP000157984    UP000138593    UP000006570    UP000118513    UP000131329    UP000150494    UP000126363    UP000128919    UP000159980    UP000102617    UP000157996    UP000172322    UP000143770    UP000128853    UP000007450    UP000100289    UP000110240    UP000128606    UP000164299    UP000140614    UP000161940    UP000154720    UP000129833    UP000125672    UP000006573    UP000133539    UP000136409    UP000102490    UP000144982   

PRIDE

P59635   

Pfam

PF08779   SARS_X4

Interpro

IPR036495   SARS_X4_sf
IPR014888   SARS_X4

SUPFAM

SSF117066   SSF117066

Gene 3D

2.60.40.1550    

ProteinModelPortal

D2E2E4   Q6RD14   Q6SRQ5   Q692D8   Q6RD58   Q6T1D6   + More
Q6VA94   Q6SRX0   Q6VA72   Q6SRT0   Q6RCY1   C4P6R3   Q1EFN9   Q6RD25   Q6RD03   Q6SRT5   Q1EFM6   Q6SRV5   Q3ZTB9   Q6RCX0   Q4JDP8   Q4JDR1   Q3S2B9   Q6SRV0   Q3ZTD4   Q6SRW5   Q6RD36   Q6SRW0   Q6SRS5   Q6R7Y0   Q6VA83   Q6SRY5   Q6SRU0   Q6SRR5   Q5Y181   Q6SRR0   Q6SRY0   Q6S8D1   Q6SRS0   Q6RCV9   Q6RCZ2   Q3ZTE7   Q6SRX5   Q6SRZ0   Q6RD47   Q76XZ9   Q6SRU5   Q19QW4   Q6SZ88   D2E1F3   D2E227   D2E1D8   D2E271   D3KDN1   P59635   A7J8M0   D2E2I7   Q6GYQ5   J9TEN5   J9T5H6   J9SF21   A0A0K1Z075   A0A0K1Z059   A0A1W6S796   D2DJX0   U5WI44   U5WIM6   A0A2D1PX67   A0A2D1PXH7   A0A2D1PXE3   Q3I5J0   D5HJV0   D5HJT9   A0A023PUX1   A0A2D1PXB5   D5HJS8   D5HJW3   D5HJR7   D5HJX4   D5HJQ6   D5HJY5   Q3LZU5   D5HK07   Q3LZX7   A0A2D1PXB6   A0A0U2ND36   U5WI16   A0A0U1UZF3   Q3LZU8   A0A0U1UZE6   A0A0U1UZE3   A0A0U1UZD9   A0A0U1UZE9   Q0QDX4   Q0Q470   Q0QDY4   Q0Q479   A0A166ZLD3   A0A221ZS13   D5HJZ6  

PDB

1YO4     E-value=1.42549e-43,     Score=437