Strain

CHINA_BAT_2006_NC_009020 (Region: China: Guangdong province;  Strain: Bat coronavirus HKU5-1, complete genome.;  Date: 2006)

Gene

spike glycoprotein

Description

Annotated in NCBI,  spike glycoprotein

Location

NC_009020(+):21735-25793

GenBank Accession

YP_001039962.1

Full name

Spike glycoprotein      

Alternative Name

E2
Peplomer protein

CDS

ATGATACGCTCAGTGTTAGTACTGATGTGCTCGTTAACTTTTATAGGAAACCTCACAAGAGGTCAAAGTGTTGATATGGGACACAATGGCACTGGTTCATGTTTAGATTCCCAGGTACAACCTGATTATTTTGAATCTGTGCATACTACTTGGCCCATGCCTATTGACACGAGTAAGGCTGAAGGTGTCATTTATCCTAATGGCAAGTCCTACTCTAATATTACTCTAACTTATACGGGACTGTACCCCAAGGCTAATGACCTTGGTAAACAGTATTTATTCTCTGACGGACATAGTGCCCCAGGACGTCTTAATAACTTATTTGTCAGTAATTACTCCTCACAAGTGGAGTCCTTTGATGATGGCTTTGTGGTCCGTATTGGTGCTGCTGCCAATAAAACTGGAACCACTGTCATATCTCAATCCACATTTAAACCCATTAAGAAAATCTATCCAGCCTTTTTGCTTGGACATTCTGTGGGTAATTATACACCGTCCAATAGGACAGGTCGTTATCTCAACCACACGCTTGTCATCCTACCGGATGGCTGTGGTACTATTTTACATGCATTCTATTGTGTTCTTCACCCTCGCACACAACAAAATTGTGCTGGTGAAACAAATTTCAAATCCCTCTCGCTTTGGGATACTCCTGCATCAGACTGTGTCTCTGGTTCTTATAACCAAGAAGCCACATTAGGTGCTTTCAAAGTGTATTTTGACTTGATTAATTGCACGTTCAGATACAATTATACTATAACAGAGGATGAAAACGCTGAGTGGTTCGGCATTACCCAAGACACACAAGGCGTTCACCTCTATTCATCTCGAAAAGAGAACGTGTTCAGAAATAACATGTTCCACTTTGCTACTTTACCTGTGTACCAGAAAATCCTCTATTACACAGTCATTCCTCGCAGCATCCGAAGTCCTTTCAATGACAGAAAAGCCTGGGCTGCATTCTACATTTATAAACTACATCCACTCACATATTTGCTAAATTTTGATGTGGAGGGCTATATAACTAAAGCTGTAGACTGTGGCTACGATGATCTAGCACAGCTACAATGTTCCTACGAATCCTTCGAAGTCGAAACAGGCGTTTATTCCGTTTCATCGTTCGAAGCTTCTCCTAGAGGTGAGTTCATTGAACAGGCAACAACTCAAGAGTGTGATTTCACACCTATGTTGACTGGTACACCTCCTCCTATATATAATTTCAAAAGGTTGGTCTTCACCAATTGCAATTACAACTTAACAAAACTCCTTTCACTGTTTCAAGTGAGCGAGTTTTCTTGTCATCAAGTTTCACCTAGTAGTCTTGCTACCGGTTGTTACTCTTCTCTTACAGTGGACTATTTCGCTTATTCCACTGATATGAGTTCTTACCTGCAACCTGGCTCCGCTGGAGCAATTGTGCAGTTTAATTACAAACAAGACTTTAGCAATCCCACGTGTAGAGTGCTTGCTACTGTTCCACAAAATCTTACTACAATTACTAAACCTAGTAATTATGCTTATCTTACAGAGTGTTATAAAACCAGTGCATATGGCAAGAATTACTTGTACAATGCGCCTGGCGCTTACACTCCTTGCTTATCTTTAGCCTCTCGTGGGTTCTCTACTAAATACCAGTCACATAGTGATGGCGAGCTAACCACTACTGGTTACATTTATCCTGTCACTGGAAATCTTCAAATGGCTTTCATAATTTCTGTTCAGTATGGAACTGACACTAACAGTGTCTGCCCCATGCAAGCATTAAGAAATGATACTAGCATTGAAGATAAGCTAGACGTTTGTGTTGAATACTCGCTCCATGGTATAACTGGAAGGGGGGTTTTCCACAATTGCACATCTGTTGGACTGAGAAACCAGCGGTTTGTGTATGATACTTTCGACAATTTAGTTGGTTACCATTCTGACAATGGTAATTACTATTGTGTCAGACCTTGTGTCAGTGTGCCTGTCTCTGTGATTTACGACAAGGCATCTAATTCTCATGCTACATTATTCGGAAGCGTTGCATGTTCGCACGTTACCACAATGATGTCGCAATTTTCACGCATGACCAAAACTAATTTGCTCGCGCGTACAACTCCAGGTCCATTGCAAACTACTGTTGGTTGTGCAATGGGCTTTATCAATTCCTCAATGGTAGTTGACGAATGTCAACTTCCGCTTGGTCAATCACTTTGTGCTATTCCACCAACTACTTCTTCACGCGTTCGACGTGCTACTTCTGGTGCATCTGATGTGTTTCAAATCGCCACTCTTAACTTTACTAGTCCATTAACACTCGCACCAATAAATTCTACTGGATTTGTTGTTGCTGTGCCGACTAATTTCACATTTGGTGTCACTCAAGAATTCATTGAGACTACCATTCAAAAGATTACTGTCGATTGCAAGCAGTACGTTTGTAATGGTTTTAAGAAGTGCGAAGACTTGCTCAAAGAATATGGCCAGTTTTGCTCTAAAATTAACCAGGCTCTTCATGGTGCAAACCTACGTCAAGACGAGTCTATTGCTAATCTATTTTCAAGTATTAAAACCCAGAATACCCAGCCTCTTCAGGCGGGATTGAATGGTGATTTTAACTTGACTATGCTTCAAATACCTCAAGTTACTACAGGTGAACGTAAGTACAGGAGTACTATCGAAGACCTTCTTTTCAATAAGGTTACTATTGCTGATCCTGGCTATATGCAAGGCTATGATGAATGTATGCAGCAAGGTCCTCAGTCAGCTCGAGACTTGATCTGTGCACAATATGTTGCTGGCTACAAAGTGCTGCCACCCTTATATGACCCCTATATGGAAGCTGCTTACACTTCTTCCCTATTGGGCAGTATTGCTGGTGCTAGTTGGACAGCAGGTCTGTCGTCTTTCGCAGCAATACCATTTGCACAAAGTATCTTTTATCGCTTGAATGGTGTTGGCATCACTCAGCAGGTTCTGTCTGAGAATCAGAAGATCATTGCCAACAAATTCAATCAAGCTCTTGGTGCCATGCAAACTGGCTTTACTACTACTAACCTTGCTTTCAACAAGGTTCAGGATGCAGTAAATGCTAATGCAATGGCTCTTTCCAAACTAGCTGCGGAATTGTCTAACACTTTCGGTGCTATTTCATCATCAATCAGTGACATCCTTGCAAGGCTTGACACTGTTGAACAAGAGGCTCAAATTGATCGGTTGATCAATGGACGTCTTACATCCCTTAACGCATTCGTTGCGCAACAACTCGTGCGTACTGAAGCTGCTGCTAGATCTGCCCAATTGGCTCAAGATAAGGTCAATGAGTGCGTGAAGTCGCAATCCAAACGGAATGGATTCTGCGGAACTGGCACACATATTGTTTCATTTGCCATTAATGCTCCTAATGGCCTCTACTTCTTCCATGTTGGTTACCAGCCAACATCCCATGTCAATGCAACTGCCGCTTATGGCCTTTGCAACACTGAAAATCCACAAAAGTGCATTGCACCTATTGATGGATACTTCGTCTTAAACCAAACTACCAGCACTGTCGCAGACAGTGACCAACAATGGTATTATACTGGTAGTTCCTTCTTCCATCCTGAACCCATCACAGAAGCAAATTCTAAGTATGTGTCCATGGATGTAAAATTCGAAAACCTCACTAATAGGCTTCCTCCACCGCTCCTTAGTAATTCAACAGATTTGGATTTCAAGGAAGAGCTGGAAGAATTCTTCAAAAACGTCTCCTCACAAGGACCAAACTTCCAGGAGATTTCTAAGATTAACACTACACTGCTTAACCTCAACACAGAGTTGATGGTGCTGAGTGAAGTTGTTAAACAATTAAATGAATCCTATATCGACTTGAAAGAGTTGGGGAATTATACTTTTTACCAAAAATGGCCATGGTATATATGGCTTGGCTTTATTGCAGGGCTTGTTGCTCTTGCTCTTTGTGTGTTCTTCATCTTATGCTGTACTGGCTGTGGTACTAGCTGTTTGGGGAAACTAAAATGTAATCGTTGTTGTGACTCGTATGATGAGTATGAGGTCGAGAAGATCCATGTTCATTGA

Protein

MIRSVLVLMCSLTFIGNLTRGQSVDMGHNGTGSCLDSQVQPDYFESVHTTWPMPIDTSKAEGVIYPNGKSYSNITLTYTGLYPKANDLGKQYLFSDGHSAPGRLNNLFVSNYSSQVESFDDGFVVRIGAAANKTGTTVISQSTFKPIKKIYPAFLLGHSVGNYTPSNRTGRYLNHTLVILPDGCGTILHAFYCVLHPRTQQNCAGETNFKSLSLWDTPASDCVSGSYNQEATLGAFKVYFDLINCTFRYNYTITEDENAEWFGITQDTQGVHLYSSRKENVFRNNMFHFATLPVYQKILYYTVIPRSIRSPFNDRKAWAAFYIYKLHPLTYLLNFDVEGYITKAVDCGYDDLAQLQCSYESFEVETGVYSVSSFEASPRGEFIEQATTQECDFTPMLTGTPPPIYNFKRLVFTNCNYNLTKLLSLFQVSEFSCHQVSPSSLATGCYSSLTVDYFAYSTDMSSYLQPGSAGAIVQFNYKQDFSNPTCRVLATVPQNLTTITKPSNYAYLTECYKTSAYGKNYLYNAPGAYTPCLSLASRGFSTKYQSHSDGELTTTGYIYPVTGNLQMAFIISVQYGTDTNSVCPMQALRNDTSIEDKLDVCVEYSLHGITGRGVFHNCTSVGLRNQRFVYDTFDNLVGYHSDNGNYYCVRPCVSVPVSVIYDKASNSHATLFGSVACSHVTTMMSQFSRMTKTNLLARTTPGPLQTTVGCAMGFINSSMVVDECQLPLGQSLCAIPPTTSSRVRRATSGASDVFQIATLNFTSPLTLAPINSTGFVVAVPTNFTFGVTQEFIETTIQKITVDCKQYVCNGFKKCEDLLKEYGQFCSKINQALHGANLRQDESIANLFSSIKTQNTQPLQAGLNGDFNLTMLQIPQVTTGERKYRSTIEDLLFNKVTIADPGYMQGYDECMQQGPQSARDLICAQYVAGYKVLPPLYDPYMEAAYTSSLLGSIAGASWTAGLSSFAAIPFAQSIFYRLNGVGITQQVLSENQKIIANKFNQALGAMQTGFTTTNLAFNKVQDAVNANAMALSKLAAELSNTFGAISSSISDILARLDTVEQEAQIDRLINGRLTSLNAFVAQQLVRTEAAARSAQLAQDKVNECVKSQSKRNGFCGTGTHIVSFAINAPNGLYFFHVGYQPTSHVNATAAYGLCNTENPQKCIAPIDGYFVLNQTTSTVADSDQQWYYTGSSFFHPEPITEANSKYVSMDVKFENLTNRLPPPLLSNSTDLDFKEELEEFFKNVSSQGPNFQEISKINTTLLNLNTELMVLSEVVKQLNESYIDLKELGNYTFYQKWPWYIWLGFIAGLVALALCVFFILCCTGCGTSCLGKLKCNRCCDSYDEYEVEKIHVH

Function

attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.
mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.
Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
Spike protein S1: attaches the virion to the cell membrane by interacting with host receptor, initiating the infection.
Spike protein S2': Acts as a viral fusion peptide which is unmasked following S2 cleavage occurring upon virus endocytosis.
Spike protein S2: mediates fusion of the virion and cellular membranes by acting as a class I viral fusion protein. Under the current model, the protein has at least three conformational states: pre-fusion native state, pre-hairpin intermediate state, and post-fusion hairpin state. During viral and target cell membrane fusion, the coiled coil regions (heptad repeats) assume a trimer-of-hairpins structure, positioning the fusion peptide in close proximity to the C-terminal region of the ectodomain. The formation of this structure appears to drive apposition and subsequent fusion of viral and target cell membranes.

Subunit

Homotrimer; each monomer consists of a S1 and a S2 subunit. The resulting peplomers protrude from the virus surface as spikes.

Similarity

Belongs to the betacoronaviruses spike protein family.

Keywords

3D-structure   Coiled coil   Disulfide bond   Fusion of virus membrane with host endosomal membrane   Fusion of virus membrane with host membrane   Glycoprotein   Host cell membrane   Host membrane   Host-virus interaction   Lipoprotein   Membrane   Palmitate   Reference proteome   Signal   Transmembrane   Transmembrane helix   Viral attachment to host cell   Viral envelope protein   Viral penetration into host cytoplasm   Virion   Virulence   Virus entry into host cell  

Feature

chain  Spike glycoprotein

Uniprot

A3EXD0   S4WZQ4   S4X422   S4WWR8   S4WZR3   S4WWS3   + More
A0A0U1WHM0   S4WZR0   S4X278   S4X284   S4WWR5   A3EXD9   A3EXE8   A3EXF7   S4WYF2   S4WYE5   S4X419   S4WYE8   S4X425   S4X276   Q0Q4F7   A0A2I6PIW5   A0A2I6PIX8   A0A023Y9K3   A0A2I4R8V9   A0A2I4R888   A0A2R4KP93   A0A2R4KP86   A0A5H2WTJ3   A0A1Z1W230   A0A1Z1W244   S4WYD2   Q0Q4F2   A0A1Z1W227   S4WWQ3   S4WZQ1   A0A166ZLN4   S4WYD6   A3EXA3   A3EX94   A3EXC1   A3EXB2   A0A0U1WJZ6   A0A140AZ05   A0A0A0Q4U2   A0A0P0HTL4   A0A291I6G6   A0A0U2J5T6   A0A0U2INY2   A0A126G7Z3   A0A0U2MGJ8   A0A0U2MS80   A0A2H1YPP7   A0A0P0GPV1   A0A140AQ46   A0A0U2NTX5   A0A0U4AGH8   A0A0P0HJE7   A0A2D0YM48   A0A2D0YGK8   A0A0P0HBE6   A0A0U2P9C9   A0A0A0Q7F8   A0A0U2NE92   A0A0A0Q7G4   A0A2D0YIQ0   A0A1D6Y6X4   A0A0U2P188   A0A0U2J5U2   A0A2D0YCT4   T2B9T0   A0A0U2GMX5   T2B999   A0A0U2GLS2   W5ZZF5   A0A0U2MS90   A0A0U2NXW5   A0A3T0I8D8   A0A0G3U597   A0A2D0YCE0   R9UCW7   A0A1C8EAZ2   A0A0U2GPS7   A0A0U2P195   A0A291I6B7   A0A3S7R2I2   K0BRG7   A0A384VXU1   W6A028   A0A411PBL8   A0A2D0YNJ0   A0A2D0YPZ8   A0A2D0YAP4   A0A0U3SQE0   A0A2D0Y380   A0A0U2NE84   A0A2D0YDA3   A0A1W5LGU2   A0A5J6ED89   A0A140AZ15  

Pubmed

17121802    23720729    16840328    29258555    24960574    28589292    + More
26847648    26933050    25323704    26678874    27486688    26814649    29116217    24055451    24549846    24857749    24896817    31553909    31022948    26272558    23782859    23170002    26391698    24781747    26079346    26584223    26272560    26691200    26981770    27999424    26839489    30753126   

EMBL

EF065509    KC522090    AGP04929.1    KC522099    AGP04938.1    KC522098    + More
AGP04937.1    KC522100    AGP04939.1    KC522103    AGP04942.1    KJ473820    AIA62343.1    KC522095    AGP04934.1    KC522096    AGP04935.1    KC522101    AGP04940.1    KC522093    AGP04932.1    EF065510    ABN10884.1    EF065511    ABN10893.1    EF065512    ABN10902.1    KC522102    AGP04941.1    KC522092    AGP04931.1    KC522094    AGP04933.1    KC522097    AGP04936.1    KC522104    AGP04943.1    KC522091    AGP04930.1    DQ648790    ABG11962.1    MG596802    AUM60014.1    MG596803    AUM60024.1    KJ473821    AHY61337.1    KX442564    ASL68941.1    KX442565    ASL68953.1    MG021452    AVV62537.1    MG021451    AVV62526.1    LC469308    BBJ36008.1    KY783843    ARX80139.1    KY783844    ARX80140.1    KC522049    AGP04916.1    DQ648794    KY783842    ARX80138.1    KC522050    AGP04917.1    KC522057    AGP04924.1    KU182965    ANA96039.1    KC522051    KC522052    KC522053    KC522054    KC522055    KC522056    KC522058    KC522059    KC522060    KC522061    AGP04918.1    AGP04919.1    AGP04920.1    AGP04921.1    AGP04922.1    AGP04923.1    AGP04925.1    AGP04926.1    AGP04927.1    AGP04928.1    EF065506    ABN10848.1    EF065505    EF065508    ABN10866.1    EF065507    ABN10857.1    KJ473822    AIA62352.1    KT868875    KX034094    KX034095    ALK80291.1    ANC28645.1    ANC28656.1    KM027279    KT368824    AID55090.1    ALA49341.1    KR912188    KR912195    KU710264    ALJ76278.1    AMQ48993.1    MG011356    ATG84855.1    KT806006    ALJ54486.1    KT806041    ALJ54521.1    KT374057    ALB08322.1    KT806016    ALJ54496.1    KT805987    ALJ54467.1    MF598597    ASU89955.1    KR912187    ALJ76277.1    KT374056    ALB08311.1    KT806028    ALJ54508.1    KT806049    ALW82691.1    KR912196    ALJ76286.1    MF598638    ASU90406.1    MF598608    MF598650    MF598700    ASU90076.1    ASU90538.1    ASU91087.1    KT368828    KT368843    KT368844    KT368845    KT368849    KT368850    KT368851    KT368855    KT368887    KT368888    KT805995    KT805997    KT805998    KT805999    KT806000    KT806013    KR912189    KR912190    KR912191    KR912192    KR912193    KR912194    KT877351    ALA49385.1    ALA49550.1    ALA49561.1    ALA49572.1    ALA49616.1    ALA49627.1    ALA49638.1    ALA49682.1    ALA50034.1    ALA50045.1    ALJ54475.1    ALJ54477.1    ALJ54478.1    ALJ54479.1    ALJ54480.1    ALJ54493.1    ALJ76282.1    ALL26409.1    KT805970    KT806001    KT806004    ALJ54450.1    ALJ54481.1    ALJ54484.1    KM027273    AID55084.1    KT806010    ALJ54490.1    KM027288    AID55099.1    MF598711    ASU91208.1    KT861627    ALX27232.1    KT806021    ALJ54501.1    KT806038    ALJ54518.1    MF598641    ASU90439.1    KF600652    KT806040    AGV08584.1    ALJ54520.1    KT368880    KT368881    ALA49957.1    ALA49968.1    KF600612    KF600620    AGV08379.1    AGV08408.1    KT368866    KT368867    ALA49803.1    ALA49814.1    KF917527    KF958702    KJ156949    KJ156952    KJ556336    AHE78097.1    AHE78108.1    AHI48594.1    AHI48605.1    AHN10812.1    KT805978    KT806003    ALJ54458.1    ALJ54483.1    KT805972    KT806055    ALJ54452.1    ALW82753.1    MK280984    AZU90731.1    KT029139    AKL59401.1    MF598631    ASU90329.1    KF192507    AGN52936.1    KT877350    ALL26396.1    KT368852    ALA49649.1    KT806037    ALJ54517.1    MG011354    ATG84833.1    MG757597    AXN73437.1    JX869059    AFS88936.1    MF741827    MF741832    ASY99811.1    ASY99864.1    KJ156934    KJ156873    KJ713295    KJ713296    KM015348    KM027281    KM210278    KP966104    KT006149    KT026453    KT026454    KT026455    KT026456    KT036372    KT036373    KT036374    KT182953    KT275306    KT275307    KT275308    KT368833    KT368868    KT368870    KT368871    KT368872    KT368873    KT368874    KT368876    KT368877    KT368878    KT368882    KT368883    KT368884    KT368885    KT368886    KT368889    KT805964    KT805965    KT805967    KT805969    KT805974    KT805977    KT805979    KT805980    KT805982    KT805984    KT805989    KT805990    KT805993    KT805996    KT806002    KT806005    KT806007    KT806009    KT806012    KT806014    KT806018    KT806019    KT806023    KT806024    KT806025    KT806026    KT806027    KT806029    KT806030    KT806031    KT806033    KT806034    KT806035    KT806039    KT868870    KU233362    KU233363    KU233364    KT806044    KT806045    KT806046    KT806047    KT806048    KT806050    KT806051    KT806052    KT806053    KU851859    KU851860    KU851861    KU851862    KU851863    KU851864    KX154684    KX108945    KY688118    KY688120    KY688121    KY688122    KY688123    KY688124    MF598594    MF598595    MF598603    MF598604    MF598606    MF598607    MF598611    MF598612    MF598613    MF598615    MF598620    MF598625    MF598627    MF598628    MF598633    MF598643    MF598644    MF598645    MF598646    MF598652    MF598654    MF598657    MF598660    MF598661    MF598662    MF598664    MF598665    MF598666    MF598668    MF598670    MF598677    MF598680    MF598682    MF598684    MF598685    MF598686    MF598687    MF598688    MF598691    MF598692    MF598694    MF598695    MF598697    MF598698    MF598701    MF741837    MF741825    MF741826    MF741828    MF741829    MF741831    MF741833    MF741834    MF741835    MF741836    MG011343    MG011352    MG011353    MG011355    MF679172    MG366880    MG912608    MH306207    MH371127    MH432120    MG757593    MG757594    MG757595    MG757596    MG757598    MG757599    MG757600    MG757601    MG757602    MG757603    MH029552    MK129253    MH978888    MK462248    MH259486    MK858156    MK858158    MK858163    AHI48572.1    AHI48662.1    AHY22525.1    AHY22535.1    AID50418.1    AID55092.1    AJD81451.1    AKA63509.1    AKJ80137.2    AKK52582.1    AKK52592.1    AKK52602.1    AKK52612.1    AKL80593.1    AKL80604.1    AKL80615.1    AKN11071.1    AKQ21055.1    AKQ21064.1    AKQ21073.1    ALA49440.1    ALA49825.1    ALA49847.1    ALA49858.1    ALA49869.1    ALA49880.1    ALA49891.1    ALA49913.1    ALA49924.1    ALA49935.1    ALA49979.1    ALA49990.1    ALA50001.1    ALA50012.1    ALA50023.1    ALA50056.1    ALJ54444.1    ALJ54445.1    ALJ54447.1    ALJ54449.1    ALJ54454.1    ALJ54457.1    ALJ54459.1    ALJ54460.1    ALJ54462.1    ALJ54464.1    ALJ54469.1    ALJ54470.1    ALJ54473.1    ALJ54476.1    ALJ54482.1    ALJ54485.1    ALJ54487.1    ALJ54489.1    ALJ54492.1    ALJ54494.1    ALJ54498.1    ALJ54499.1    ALJ54503.1    ALJ54504.1    ALJ54505.1    ALJ54506.1    ALJ54507.1    ALJ54509.1    ALJ54510.1    ALJ54511.1    ALJ54513.1    ALJ54514.1    ALJ54515.1    ALJ54519.1    ALK80242.1    ALT66802.1    ALT66813.1    ALT66824.1    ALW82636.1    ALW82647.1    ALW82658.1    ALW82669.1    ALW82680.1    ALW82702.1    ALW82709.1    ALW82720.1    ALW82731.1    AMQ49015.1    AMQ49026.1    AMQ49037.1    AMQ49048.1    AMQ49059.1    AMQ49070.1    ANF29162.1    ANI69911.1    AQZ41311.1    AQZ41332.1    AQZ41343.1    AQZ41354.1    AQZ41365.1    AQZ41376.1    ASU89921.1    ASU89933.1    ASU90021.1    ASU90032.1    ASU90054.1    ASU90065.1    ASU90109.1    ASU90120.1    ASU90131.1    ASU90153.1    ASU90208.1    ASU90263.1    ASU90285.1    ASU90295.1    ASU90351.1    ASU90461.1    ASU90472.1    ASU90483.1    ASU90494.1    ASU90560.1    ASU90582.1    ASU90615.1    ASU90648.1    ASU90659.1    ASU90670.1    ASU90692.1    ASU90703.1    ASU90714.1    ASU90736.1    ASU90758.1    ASU90835.1    ASU90868.1    ASU90890.1    ASU90912.1    ASU90923.1    ASU90934.1    ASU90945.1    ASU90956.1    ASU90988.1    ASU90999.1    ASU91021.1    ASU91032.1    ASU91054.1    ASU91065.1    ASU91098.1    ASY99778.1    ASY99789.1    ASY99800.1    ASY99820.1    ASY99831.1    ASY99853.1    ASY99873.1    ASY99884.1    ASY99895.1    ASY99906.1    ATG84712.1    ATG84811.1    ATG84822.1    ATG84844.1    ATW75478.1    ATY74381.1    AVK87461.1    AWM99582.1    AXG21643.1    AXG21665.1    AXN73393.1    AXN73404.1    AXN73415.1    AXN73426.1    AXN73448.1    AXN73459.1    AXN73470.1    AXN73481.1    AXN73492.1    AXN73503.1    AYO86699.1    AZK15900.1    QBF44115.1    QBF80510.1    QCI31480.1    QCQ28828.1    QCQ28830.1    QCQ28835.1    MK462253    MK462254    MK462255    QBF80565.1    QBF80576.1    QBF80587.1    MF598600    MF598678    ASU89988.1    ASU90846.1    MF598632    ASU90340.1    MF598679    ASU90857.1    KT806054    ALW82742.1    MF598623    ASU90241.1    KT805994    ALJ54474.1    MF598651    ASU90549.1    KX154693    ANF29261.1    MN403102    QEU56412.1    KT868872    KT868876    ALK80261.1    ALK80301.1   

Proteomes

UP000007451    UP000148908    UP000164987    UP000143769    UP000100668    UP000124656    + More
UP000007449    UP000107989    UP000163538    UP000006574    UP000123539    UP000110642    UP000104899    UP000145271    UP000167218    UP000138672    UP000162302    UP000149108    UP000146591    UP000098431    UP000104003    UP000112676    UP000126955    UP000128936    UP000136645    UP000137287    UP000146604    UP000151733    UP000159793    UP000148810    UP000113143    UP000152659    UP000140430    UP000154518    UP000134703    UP000157238    UP000119765    UP000120438    UP000135014    UP000148657    UP000159930    UP000117213    UP000118772    UP000104220    UP000112550    UP000112279    UP000095864    UP000096875    UP000102966    UP000104540    UP000109666    UP000112022    UP000115322    UP000118563    UP000119223    UP000121965    UP000122049    UP000125198    UP000128184    UP000128186    UP000128651    UP000142239    UP000144056    UP000144472    UP000147538    UP000151795    UP000153269    UP000157492    UP000158935    UP000159306    UP000161565    UP000163035    UP000163895    UP000170921    UP000171516    UP000171892    UP000174054    UP000174558    UP000180347    UP000180348    UP000171389   

PRIDE

A3EXD0    Q0Q4F2    A3EX94   

Pfam

PF09408   Spike_rec_bind
PF01601   Corona_S2

Interpro

IPR002552   Corona_S2
IPR018548   Spike_rcpt-bd
IPR027400   S_HR2
IPR036326   Spike_rcpt-bd_sf
IPR042578   BETA_CORONA_SPIKE
IPR043002   Spike_N_sf

SUPFAM

SSF143587   SSF143587

Gene 3D

1.20.5.790     2.60.120.960    

ProteinModelPortal

A3EXD0   S4WZQ4   S4X422   S4WWR8   S4WZR3   S4WWS3   + More
A0A0U1WHM0   S4WZR0   S4X278   S4X284   S4WWR5   A3EXD9   A3EXE8   A3EXF7   S4WYF2   S4WYE5   S4X419   S4WYE8   S4X425   S4X276   Q0Q4F7   A0A2I6PIW5   A0A2I6PIX8   A0A023Y9K3   A0A2I4R8V9   A0A2I4R888   A0A2R4KP93   A0A2R4KP86   A0A5H2WTJ3   A0A1Z1W230   A0A1Z1W244   S4WYD2   Q0Q4F2   A0A1Z1W227   S4WWQ3   S4WZQ1   A0A166ZLN4   S4WYD6   A3EXA3   A3EX94   A3EXC1   A3EXB2   A0A0U1WJZ6   A0A140AZ05   A0A0A0Q4U2   A0A0P0HTL4   A0A291I6G6   A0A0U2J5T6   A0A0U2INY2   A0A126G7Z3   A0A0U2MGJ8   A0A0U2MS80   A0A2H1YPP7   A0A0P0GPV1   A0A140AQ46   A0A0U2NTX5   A0A0U4AGH8   A0A0P0HJE7   A0A2D0YM48   A0A2D0YGK8   A0A0P0HBE6   A0A0U2P9C9   A0A0A0Q7F8   A0A0U2NE92   A0A0A0Q7G4   A0A2D0YIQ0   A0A1D6Y6X4   A0A0U2P188   A0A0U2J5U2   A0A2D0YCT4   T2B9T0   A0A0U2GMX5   T2B999   A0A0U2GLS2   W5ZZF5   A0A0U2MS90   A0A0U2NXW5   A0A3T0I8D8   A0A0G3U597   A0A2D0YCE0   R9UCW7   A0A1C8EAZ2   A0A0U2GPS7   A0A0U2P195   A0A291I6B7   A0A3S7R2I2   K0BRG7   A0A384VXU1   W6A028   A0A411PBL8   A0A2D0YNJ0   A0A2D0YPZ8   A0A2D0YAP4   A0A0U3SQE0   A0A2D0Y380   A0A0U2NE84   A0A2D0YDA3   A0A1W5LGU2   A0A5J6ED89   A0A140AZ15  

PDB

5X5F     E-value=0,     Score=4117