Strain

AMERICA_WHALE_2007_NC_010646 (Region: North America;  Strain: Beluga Whale coronavirus SW1, complete genome.;  Date: 2007)

Gene

matrix glycoprotein

Description

Annotated in NCBI,  matrix glycoprotein

Location

NC_010646(+):25145-25927

GenBank Accession

YP_001876439.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGGTGAATATGTATGAAGTAGCGCTTCGTGTGCTTCGTGATTACAATTTAGCATTATCAGCGTTTCTGACATTGATTATTTGTGTGTTACAGTTTGGTTATGCCTCCCGTAACAGGTTCTTTTATTGGATTAAGATTATTACTTTGTGGCTTATGTGGCCGTTTGCTATTGTAACGTCGGTGTTTTCATGTTTGTATCCACCATGTTATAGTTATGCCTCTAGGTTTAGTAATAACACTTCCACCACTCCAACACCAGTTGAAGGTAATGGTTTGTGGTCATGTGGTTCTAGTTATGCAATTTCTGTTAACCTTACTGCATTTGTGTTTGCAATAATTTTTGCAATTTTCACATGTGCGGCATGGCTATTTTATTGGATACAATCCACACGCCTGTATTTGAGAGTAAGATCATGGTGGGCTTTCTCACCAGACACTAACTACGTTGCTGTATTTAAAATGGCTAATGACCAGTATTTCACGCTGCCTTTGCTTGAAGTGCCTATGGTTCTTAGTCTTGTTTATAAGAATAATTTTGTTTATTGTAATGGTACATATCTTGGCAGAATACCCAGTATGGGTTATTTACCCGCTAGTTGTATAGTAGGTAGTGCCGAGAAAATTGCTAGATACAGAAAAATTACAGTTTCAGCAGCAGATGGCAGTGATGCTAATGTTGCGCGTTTTGGTACTGTGATTTATGCTAAAGATAAATATATAAGTGCAGGGCTTGCGTATACTAAGAGAGAGAAAACTGAGACAGAGAAGCTTTATTCCGTTTAA

Protein

MVNMYEVALRVLRDYNLALSAFLTLIICVLQFGYASRNRFFYWIKIITLWLMWPFAIVTSVFSCLYPPCYSYASRFSNNTSTTPTPVEGNGLWSCGSSYAISVNLTAFVFAIIFAIFTCAAWLFYWIQSTRLYLRVRSWWAFSPDTNYVAVFKMANDQYFTLPLLEVPMVLSLVYKNNFVYCNGTYLGRIPSMGYLPASCIVGSAEKIARYRKITVSAADGSDANVARFGTVIYAKDKYISAGLAYTKREKTETEKLYSV

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.

Similarity

Belongs to the gammacoronaviruses M protein family.

Keywords

Glycoprotein   Host Golgi apparatus   Host membrane   Membrane   Transmembrane   Transmembrane helix   Viral envelope protein   Viral matrix protein   Virion   Reference proteome  

Feature

chain  Membrane protein

Uniprot

B2BW35   V5TGF3   V5TFF2   C5IZI4   B3VZS5   A0A481NU89   + More
C5IZJ0   C5IZJ2   C5IZI5   C5IZI6   A0A5J6RCQ6   G4RJ98   G3C785   K7RWV4   C5IUA3   C6KCX8   A5Z0Z4   A0A5J6RC67   A0A1W6AWK4   K7S5A6   C1KAC3   C6KCX1   A0A140HEW9   A0A0A1G0F9   A0A5J6RDV5   E9LUF4   A4ZCQ8   A5Z142   C6KCY2   B3GPG8   A0A5J6RDK2   A0A5J6RDL5   J9WMJ2   J9WRY4   A0A1B2CWH4   A0A0U1WJZ5   G4RJ75   A0A1B0Z544   P12649   A0A1P8SFM3   A0A1P8FCL8   C5IUA4   Q6DTU8   Q64FZ0   A5Z149   C6KCX4   C6KCX5   A0A140DP47   Q80RY9   A0A1L1XGR3   A0A516UWB7   A0A1P8SMJ8   C6KCY0   U5U9J5   C7DY52   G4RJ95   A0A0D4CG32   C4PE61   F4MIY0   Q9J3N8   J9WLU4   I7B3F0   A0A1W6AWL0   Q6VUR2   P69606   P69607   A0A142IJS1   A0A5J6RDM6   A4ZCM9   Q6R4P1   Q58J43   A4ZCJ2   C7S863   A0A481NUK2   Q7T9P6   G3FEJ2   G4RJ86   A0A1P8FCE8   C9DST0   B3VN11   C7S7Z4   U5YDU7   Q7TEH1   A0A0C5GXD2   Q91SA2   A0A4V6MBA0   Q6W9D6   P69604   P69603   P69605   I7AZ79   A0A346M350   G4RJA1   A4ZCV6   A0A1P8VF79   A0A0U1UZF0   A0A0U1WK58   Q910H8   A0A346M361  

Pubmed

18353961    24227844    31561498    21994806    18295413    23171741    + More
22966194    18045937    29141204    2841803    27793730    15722532    26482289    26616599    15019237    21539870    11087096    21909766    23203570    28495648    28646651    30526618    16934878    21049275    22542436    25721384    15183070    16927130    23182435    20022075    25843651    19100792    20652731    23178317   

EMBL

EU111742    ABW87822.1    KF793825    AHB63497.1    KF793824    KF793826    + More
AHB63483.1    AHB63510.1    FJ976459    ACR16060.1    EU826085    ACE95721.1    MH151328    QAV53736.1    FJ976465    ACR16066.1    FJ976467    ACR16068.1    FJ976460    ACR16061.1    FJ976461    ACR16062.1    MK887107    QEY95712.1    FJ849823    ACZ67645.1    GU393332    ADV71743.1    JX565012    MH924835    MK142676    AFV92602.1    AZA07518.1    QCX41899.1    FJ965348    GQ174475    ACR55677.1    ACS45207.1    GQ174481    ACS45213.1    EF602444    ABQ84802.1    MK887111    QEY95716.1    KY626044    ARJ35785.1    JX565011    AFV92601.1    FJ807653    GQ179645    JF893452    KF663560    ACO37578.1    ACS45205.1    AEJ80242.1    AHB74003.1    GQ174474    HQ283475    HQ850618    ACS45206.1    ADT91599.1    AEB00719.1    KT886454    AMO03296.1    KM213963    AIY51832.1    MK887104    MK887108    QEY95709.1    QEY95713.1    HQ141058    ADW77296.1    DQ490214    ABF61535.1    EF602450    KY799582    ABQ84850.1    AVI69489.1    GQ174485    ACS45217.1    EU714034    GQ227602    KF377577    KP036503    KP036504    KP118880    KP118881    KP118882    KP118883    KP118884    KP118885    KP118887    KP118888    KP118891    KP118893    MK032177    MK032179    MK032180    ACD93207.1    ACT55271.1    AGY56144.1    AJP16725.1    AJP16734.1    AJT47846.1    AJT47855.1    AJT47864.1    AJT47873.1    AJT47882.1    AJT47891.1    AJT47909.1    AJT47918.1    AJT47945.1    AJT47963.1    AZA07828.1    AZA07846.1    AZA07854.1    MK887092    QEY95697.1    MK887102    QEY95707.1    JX273191    AFS18111.1    JX273197    AFS18117.1    KX258195    ANY58998.1    KF834569    KM365468    AIB54160.1    AJP08841.1    FJ849797    FJ849800    ACZ67619.1    ACZ67622.1    KU361187    ANO81447.1    M21515    KX272465    APY20698.1    KX219801    APV46188.1    FJ965349    ACR55678.1    AY646283    AAT70776.1    AY702975    KJ425496    KP343691    KT852992    KR608272    KU356856    KT002187    AAU14252.1    AHX25996.1    AKJ66257.1    AMD40267.1    AMH39309.1    ANI21153.1    AOG62366.1    EF602451    KX252791    ABQ84857.1    APY26731.1    GQ174477    ACS45209.1    GQ174478    ACS45210.1    KT736032    AMK51952.1    AF470628    AAO33466.1    KJ940499    KR265090    AJP08751.1    ART35337.1    MK581200    MK581201    QDQ69099.1    QDQ69112.1    KX252773    APY23492.1    GQ174483    ACS45215.1    KF574761    KF558356    KX236008    KX275391    KX372250    AGZ20166.1    AHJ77582.1    APY26811.1    APZ73820.1    AQY03972.1    GQ227603    ACT55272.1    FJ849820    ACZ67642.1    KP118886    AJT47900.1    FJ919617    ACQ91091.1    FJ904721    ADA83551.1    AF202999    AF206266    AF206267    AF206268    AF206269    AF206270    AF206271    JX273195    AFS18115.1    JX014375    AFN88521.1    KY626045    ARJ35795.1    AY325728    AY325729    GQ174486    FJ904720    FJ904723    GQ504724    GQ504725    JQ693036    KJ425504    KJ425508    KY805845    KY273667    MH539771    MH539772    MK728875    MK937830    MK937833    AAP86204.1    ACS45218.1    ADA83541.1    ADA83571.1    ADP06501.1    ADP06511.1    AFZ88831.1    AHX26068.1    AHX26104.1    ARS23143.1    ASF20084.1    AZP23934.1    AZP23944.1    QCE31537.1    QDA76313.1    QDA76340.1    AF363609    AF343343    AF286184    DQ834384    AY851295    AY044184    AF286185    KT946798    MG517474    AMR60484.1    AYD78153.1    MK887112    QEY95717.1    DQ490210    DQ490211    DQ490213    DQ490218    JN983807    KF460437    KF931628    ABF61506.1    ABF61514.1    ABF61527.1    ABF61567.1    AFK30957.1    AIG54287.1    AIG54299.1    AY514485    AAS00084.1    AY942743    AAX39762.1    DQ490205    ABF61469.1    EU817497    ACJ12838.1    MH151329    QAV53737.1    AY325735    KC013541    KC119407    AAP86210.1    AFY11702.1    AFY11711.1    JF705860    JF699749    AEO86772.1    AEO88932.1    FJ849811    ACZ67633.1    KX219796    APV46143.1    GQ427173    ACV87238.1    EU780078    ACE88707.2    EU714029    ACH72808.1    KF411041    AGZ89685.1    AY302747    AAP68695.1    KP036502    AJP16716.1    AF363599    AAK50026.1    MK071267    QCS40644.1    AY302742    AY302743    AY325732    AY846835    AY856347    EF602437    EF602438    EF602439    EF602443    EU714028    EU822341    FJ807652    FJ888351    FJ919614    FJ849808    GU393335    JF330899    JF828981    JX273198    KF188434    KJ425486    KJ425487    KJ425488    KJ425490    KJ425491    KJ425492    KJ425493    KJ425494    KJ425495    KJ425497    KJ425498    KJ425499    KJ425500    KJ425501    KJ425502    KJ425503    KJ425505    KJ425506    KJ425507    KJ425509    KJ425510    KJ425511    KJ425512    KJ435284    KT203557    MG763935    MK937829    MK887093    MK887097    MK887099    MK887106    AAP68690.1    AAP68691.1    AAP86207.1    AAW56626.1    AAW83033.1    ABQ84746.1    ABQ84754.1    ABQ84762.1    ABQ84794.1    ACH72797.1    ACJ50203.1    ACO37570.1    ACQ55234.1    ACQ91088.1    ACZ67630.1    ADV71781.1    ADY62556.1    AEP84750.1    AFS18118.1    AGW24531.1    AHX25906.1    AHX25915.1    AHX25924.1    AHX25942.1    AHX25951.1    AHX25960.1    AHX25969.1    AHX25978.1    AHX25987.1    AHX26005.1    AHX26014.1    AHX26023.1    AHX26032.1    AHX26041.1    AHX26050.1    AHX26059.1    AHX26077.1    AHX26086.1    AHX26095.1    AHX26113.1    AHX26122.1    AHX26131.1    AHX26140.1    AHX26158.1    ALE71335.1    AVX27616.1    QDA76304.1    QEY95698.1    QEY95702.1    QEY95704.1    QEY95711.1    AY028295    AF203004    AF322367    JX014367    KY407556    KY407558    AFN88513.1    AQY61309.1    AQY61327.1    MG913342    AXQ05194.1    FJ849796    FJ849805    FJ849807    FJ849826    JQ801377    ACZ67618.1    ACZ67627.1    ACZ67629.1    ACZ67648.1    AFJ24941.1    DQ490221    ABF61583.1    KX302867    APZ73719.1    KF975407    KJ669722    KJ940498    KR265091    AIB54164.1    AJP08745.1    AJP08750.1    ART35345.1    KF975408    KR265087    AIB54165.1    ART35313.1    AF363601    AF363604    AY325727    EF602457    GQ504723    KX236001    MK937828    MK887103    MK887109    AAK50028.1    AAK50031.1    AAP86202.1    ABQ84905.1    ADP06488.1    APY26749.1    QDA76295.1    QEY95708.1    QEY95714.1    MG913343    AXQ05205.1   

Proteomes

UP000125413    UP000134696    UP000101112    UP000126730    UP000160499    UP000156427    + More
UP000170434    UP000107262    UP000133437    UP000174764    UP000100522    UP000105510    UP000108163    UP000109170    UP000111271    UP000121165    UP000124537    UP000136129    UP000142905    UP000146859    UP000147307    UP000149934    UP000170218    UP000118234    UP000102195    UP000138732    UP000139325    UP000159001    UP000107304    UP000102415    UP000166017    UP000169726    UP000098752    UP000107291    UP000114242    UP000117985    UP000155946    UP000165485    UP000007642    UP000096468    UP000099500    UP000123393    UP000128029    UP000160278    UP000107830    UP000119449    UP000165290    UP000172963    UP000123786    UP000139954    UP000096908    UP000105210    UP000097868    UP000102121    UP000102163    UP000103149    UP000106511    UP000108224    UP000113245    UP000113896    UP000113939    UP000118008    UP000120286    UP000120642    UP000132365    UP000136241    UP000136440    UP000138146    UP000146865    UP000149404    UP000155572    UP000158124    UP000158949    UP000159206    UP000163887    UP000165788    UP000166253    UP000167410    UP000170189    UP000170844    UP000173109    UP000173215    UP000180343    UP000132955   

Pfam

PF01635   Corona_M

Interpro

IPR002574   Corona_M
IPR042550   GAMMA_CORONA_M

ProteinModelPortal

B2BW35   V5TGF3   V5TFF2   C5IZI4   B3VZS5   A0A481NU89   + More
C5IZJ0   C5IZJ2   C5IZI5   C5IZI6   A0A5J6RCQ6   G4RJ98   G3C785   K7RWV4   C5IUA3   C6KCX8   A5Z0Z4   A0A5J6RC67   A0A1W6AWK4   K7S5A6   C1KAC3   C6KCX1   A0A140HEW9   A0A0A1G0F9   A0A5J6RDV5   E9LUF4   A4ZCQ8   A5Z142   C6KCY2   B3GPG8   A0A5J6RDK2   A0A5J6RDL5   J9WMJ2   J9WRY4   A0A1B2CWH4   A0A0U1WJZ5   G4RJ75   A0A1B0Z544   P12649   A0A1P8SFM3   A0A1P8FCL8   C5IUA4   Q6DTU8   Q64FZ0   A5Z149   C6KCX4   C6KCX5   A0A140DP47   Q80RY9   A0A1L1XGR3   A0A516UWB7   A0A1P8SMJ8   C6KCY0   U5U9J5   C7DY52   G4RJ95   A0A0D4CG32   C4PE61   F4MIY0   Q9J3N8   J9WLU4   I7B3F0   A0A1W6AWL0   Q6VUR2   P69606   P69607   A0A142IJS1   A0A5J6RDM6   A4ZCM9   Q6R4P1   Q58J43   A4ZCJ2   C7S863   A0A481NUK2   Q7T9P6   G3FEJ2   G4RJ86   A0A1P8FCE8   C9DST0   B3VN11   C7S7Z4   U5YDU7   Q7TEH1   A0A0C5GXD2   Q91SA2   A0A4V6MBA0   Q6W9D6   P69604   P69603   P69605   I7AZ79   A0A346M350   G4RJA1   A4ZCV6   A0A1P8VF79   A0A0U1UZF0   A0A0U1WK58   Q910H8   A0A346M361  

PDB

5H3O     E-value=1.26658,     Score=71