Strain

BULGARIA_BAT_2008_NC_014470 (Region: Bulgaria;  Strain: Bat coronavirus BM48-31/BGR/2008, complete genome.;  Date: 2008)

Gene

membrane protein

Description

Annotated in NCBI,  membrane protein

Location

NC_014470(+):26299-26982

GenBank Accession

YP_003858587.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGACTAACAGTAGTGCTTCTCCTCCTACGGAGACCATTACCGTAGAGCAGTTAAAACACCTACTTGAGCAATGGAACCTAGTTATAGGTTTTCTGTTTTTCGCTTGGATTCTGCTACTACAGTTTGCTTACTCCAACAGGAACAGGTTTCTTTACATAATAAAGCTTGTGTTTCTCTGGCTTCTTTGGCCAATTACACTAGCCTGCTTTGTGCTTGCTGCCGTCTACAGAATTAACTGGGTTACAGGAGGCATAGCTATAGCGATGGCCTGCATTGTGGGTCTCATGTGGCTTAGCTACTTTGTGGCTTCATTCAGGCTTTTCGCACGGACCAGGTCTTGGTGGTCTTTTAACCCAGAAACCAACATTTTGCTTAACGTGCCACTACGTGGTACCATTCTGACCAGACCGCTTCTTGAGAGTGAACTTGTCATTGGTGCTGTGATCATTCGTGGTCACCTCCGTATGGCTGGACACTCCCTTGGACGCTGTGACATTAAGGACCTCCCTAAAGAAATCACTGTTGCTACATCACGAACTCTATCTTATTACAGATTAGGAGCCTCCCAGCGTGTAGCATCTGATTCAGGTTTTGCTGTTTACCACCGCTATCGTATCGGTAATTACAAGCTAAATACCGACCACATAGGCAGTGACGACAATATTGCTTTGCTAGTACAGTAA

Protein

MTNSSASPPTETITVEQLKHLLEQWNLVIGFLFFAWILLLQFAYSNRNRFLYIIKLVFLWLLWPITLACFVLAAVYRINWVTGGIAIAMACIVGLMWLSYFVASFRLFARTRSWWSFNPETNILLNVPLRGTILTRPLLESELVIGAVIIRGHLRMAGHSLGRCDIKDLPKEITVATSRTLSYYRLGASQRVASDSGFAVYHRYRIGNYKLNTDHIGSDDNIALLVQ

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.
Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus (By similarity). Interacts with the accessory proteins 3a and 7a.

Miscellaneous

Bat coronavirus 279/2005 is highly similar to SARS-CoV (SARS-like).
Bat coronavirus HKU3 is highly similar to SARS-CoV (SARS-like).
Bat coronavirus rp3 is highly similar to SARS-CoV (SARS-like).

Similarity

Belongs to the betacoronaviruses M protein family.

Keywords

3D-structure   Glycoprotein   Host Golgi apparatus   Host membrane   Host-virus interaction   Membrane   Reference proteome   Transmembrane   Transmembrane helix   Viral envelope protein   Viral immunoevasion   Viral matrix protein   Virion  

Feature

chain  Membrane protein

Uniprot

E0XIZ6   A0A3S6GSH8   A0A0U1WJY5   R9QTB5   Q3ZTC1   Q4JDQ0   + More
Q4JDR3   Q3ZTD6   Q3ZTE9   A0A2D1PX06   A0A0U1WHK3   Q6RD16   Q6TPE4   Q6T1D8   Q6GYQ7   C4P6R1   Q1EFP1   Q6RD27   Q5DIC1   Q1EFM8   Q3S2C1   Q6RD38   Q6R7Y2   A0A2D1PX75   Q5Y183   Q66VB9   A0A4Y6GMF9   A7J8L8   P59596   Q0QDX6   Q0Q472   Q692E0   Q6QJ38   D5HJS6   D5HJW1   A0A0U1WHJ2   D5HJR5   D5HJX2   D5HJQ4   D5HJZ4   D5HJY3   Q3LZT9   D5HK05   Q3LZV0   Q3LZX9   A0A2D1PX77   D3KDM9   R9QTR4   A0A4Y6GMF2   A0A0K1YZZ2   A0A1W6S797   D2DJW8   A0A0K1Z0P4   A0A2D1PXC4   A0A1W5YKU1   A0A096XNN5   A0A2D1PX60   J9TEG5   A0A4Y6GN43   D5HJT7   Q3I5J2   A0A3G5BIZ3   D2E1F1   D2E1D6   A0A2D1PXF0   U5WL98   U5WIN4   A0A4Y6GN51   A0A0U2PLG3   U5WLC5   A0A2D1PXC6   Q19QW6   A0A3G5BJ07   D2E225   D2E269   F2YKG6   J9TBX8   Q6S8D3   Q1T6X2   B8Q8W3   Q6RD60   Q6VA96   Q6UZF3   Q6VA74   Q6JH42   Q6UZE9   B8Q8V2   Q6RCY3   B8Q8Q7   Q6RD05   Q6JH34   Q6RCX2   Q6VA85   B8Q8R8   Q6RCZ4   Q6RCW1   B8Q8T0   B8Q8U1   Q6V584   D2E210  

Pubmed

20686038    23739658    16485471    16140765    29190287    14983045    + More
14709660    18987164    16625834    14527350    14733771    16112670    19370068    12730500    12730501    12853594    12958366    12876307    12781537    12917450    15194747    15763150    16580632    16195424    16840328    15757562    20831383    20071579    16169905    22412934    20016037    28384506    30393776    14569023    20463816    24172901    26719272    17222058    16269264    14654320    16269206   

EMBL

GU190215    ADK66844.1    KY352407    APO40582.1    KJ473815    AIA62323.1    + More
JX993988    AGC74174.1    AY572038    AAU04668.1    AY686864    AAV49734.1    AY686863    AAV91635.1    AY572035    AAU04653.1    AY572034    AAU04638.1    KY417142    ATO98112.1    KJ473816    AIA62333.1    AY502927    AAR87549.1    AY390556    AAS00007.1    AH013657    AAS01068.1    AY595412    AAT52332.1    FJ882963    ACQ82729.1    AY864805    AAY60784.1    AY502926    AAR87538.1    AY772062    AAX16197.1    AY864806    AAY60797.1    DQ182595    ABA02271.1    AY502925    AAR87527.1    AY508724    AAR91590.1    KY417147    ATO98173.1    AY714217    AAU81610.1    AY702026    AAU07933.1    MK211377    QDF43832.1    DQ898174    JX163923    JX163926    JX163927    JX163928    ABI96962.1    AFR58718.1    AFR58732.1    AFR58746.1    AY278741    AY274119    AY278554    AY282752    AY304492    AY304495    AY278491    AY283794    AY283795    AY283796    AY283797    AY283798    AY278487    AY278488    AY278489    AY278490    AY279354    AY291451    AY310120    AY291315    AY463059    AY323974    AY321118    AY338174    AY338175    AY348314    AP006557    AP006558    AP006559    AP006560    AP006561    AY323977    AY362698    AY362699    AY427439    DQ412043    ABD75325.1    DQ648857    AY654624    AAT76152.1    AY536759    AAS48455.1    GQ153541    ADE34747.1    GQ153544    ADE34782.1    KJ473814    AIA62313.1    GQ153540    ADE34736.1    GQ153545    ADE34793.1    GQ153539    ADE34725.1    GQ153547    ADE34815.1    GQ153546    ADE34804.1    DQ084200    AAZ41343.1    GQ153548    ADE34826.1    DQ084199    AAZ41332.1    DQ022305    KY417143    KY417148    ATO98124.1    ATO98185.1    GU553363    GU553364    GU553365    JQ316196    JN854286    ADC35487.1    AFD56977.1    AFK10258.1    JX993987    AGC74168.1    MK211375    QDF43822.1    KP886808    AKZ19079.1    KU973692    ARO76385.1    FJ588686    ACU31036.1    KP886809    AKZ19090.1    KY417145    KY417152    ATO98149.1    ATO98235.1    KY770858    KY770859    ARI44801.1    ARI44806.1    KF294457    AID16718.1    KY417146    ATO98161.1    JX163925    AFR58704.1    MK211374    QDF43817.1    GQ153542    ADE34758.1    DQ071615    MK062179    AYV99751.1    FJ882927    FJ882932    FJ882933    FJ882934    FJ882935    FJ882936    FJ882937    FJ882938    FJ882939    FJ882946    FJ882947    FJ882949    JF292921    KF514388    KF514392    KF514394    KF514396    KF514397    KF514398    KF514399    KF514400    KF514404    KF514408    KF514409    KF514413    KF514415    KF514418    KF514419    KF514421    KF514422    KF514423    ACZ71771.1    ACZ71845.1    AEA11002.1    AGT20797.1    AGT20857.1    AGT20887.1    AGT20917.1    AGT20932.1    AGT20947.1    AGT20962.1    AGT20977.1    AGT21037.1    AGT21097.1    AGT21112.1    AGT21172.1    AGT21202.1    AGT21247.1    AGT21262.1    AGT21292.1    AGT21307.1    AGT21322.1    FJ882926    FJ882928    FJ882929    FJ882930    FJ882931    FJ882940    FJ882944    FJ882950    FJ882954    FJ882955    FJ882956    FJ882960    KF514389    KF514390    KF514391    KF514393    KF514395    KF514401    KF514402    KF514403    KF514405    KF514406    KF514410    KF514411    KF514412    KF514414    KF514416    KF514417    KF514420    ACZ71756.1    ACZ71800.1    ACZ71965.1    AGT20812.1    AGT20827.1    AGT20842.1    AGT20872.1    AGT20902.1    AGT20992.1    AGT21007.1    AGT21022.1    AGT21052.1    AGT21067.1    AGT21127.1    AGT21142.1    AGT21157.1    AGT21187.1    AGT21217.1    AGT21232.1    AGT21277.1    KY417149    ATO98197.1    KC881005    AGZ48810.1    KC881006    AGZ48822.1    MK211376    QDF43827.1    KT444582    ALK02461.1    KF367457    AGZ48835.1    KY417144    KY417151    ATO98136.1    ATO98222.1    DQ497008    ABF65840.1    MK062180    AYV99765.1    FJ882942    FJ882943    FJ882951    FJ882953    FJ882959    FJ882962    HQ890526    HQ890527    HQ890528    HQ890529    HQ890530    HQ890531    HQ890532    HQ890533    HQ890534    HQ890535    HQ890536    HQ890537    HQ890538    HQ890539    HQ890540    JF292902    JF292903    JF292904    JF292905    JF292906    ACZ71995.1    AEA10402.1    FJ882945    FJ882948    FJ882952    FJ882957    FJ882958    FJ882961    HQ890541    HQ890542    HQ890543    HQ890544    HQ890545    HQ890546    JF292907    JF292908    JF292909    JF292910    JF292911    JF292912    JF292913    JF292914    JF292915    JF292916    JF292917    JF292918    JF292919    JF292920    ACZ72039.1    AEA10627.1    JF292922    JX162087    KF514407    AEA11017.1    AFM43871.1    AGT21082.1    JX163924    AFR58690.1    AY463060    AAR86779.1    AB257344    BAE93405.1    EU371564    ACB69909.1    AY502923    AAR87505.1    AY345986    AAP94741.1    AY357075    AAR14808.1    AY345988    AAP94763.1    AY485277    AAR23248.1    AY357076    AAR14812.1    EU371563    ACB69898.1    AY502930    AAR87582.1    EU371559    ACB69853.1    AY502928    AAR87560.1    AY485278    AAR23256.1    AY502931    AAR87593.1    AY345987    AAP94752.1    EU371560    ACB69864.1    AY502929    AAR87571.1    AY502932    AAR87604.1    EU371561    ACB69876.1    EU371562    ACB69887.1    AY350750    AAR14804.1    FJ882941    ACZ71980.1   

Proteomes

UP000149701    UP000129833    UP000127630    UP000153024    UP000126514    UP000115496    + More
UP000141980    UP000127950    UP000128606    UP000174857    UP000166164    UP000158790    UP000112237    UP000133349    UP000148329    UP000156013    UP000149347    UP000163176    UP000139901    UP000117876    UP000171372    UP000105036    UP000166757    UP000180360    UP000180361    UP000180362    UP000000354    UP000103670    UP000109640    UP000116947    UP000121636    UP000131569    UP000131955    UP000137377    UP000138690    UP000143093    UP000145651    UP000146108    UP000146181    UP000146296    UP000148194    UP000153467    UP000160648    UP000164441    UP000172416    UP000125672    UP000006573    UP000101079    UP000126363    UP000128919    UP000140614    UP000159980    UP000102617    UP000157996    UP000144982    UP000172322    UP000143770    UP000128853    UP000164299    UP000007450    UP000112510    UP000152329    UP000180379    UP000180381    UP000180382    UP000106179    UP000174731    UP000122532    UP000143681    UP000119208    UP000148108    UP000131329    UP000006570    UP000097931    UP000121467    UP000125925    UP000128288    UP000150617    UP000151673    UP000151756    UP000153830    UP000155701    UP000157930    UP000160899    UP000161442    UP000161729    UP000162782    UP000164349    UP000169779    UP000173963    UP000174280    UP000180434    UP000180435    UP000180436    UP000180437    UP000180438    UP000180439    UP000180440    UP000180441    UP000180442    UP000180443    UP000180444    UP000180445    UP000180446    UP000097852    UP000106870    UP000117796    UP000119316    UP000119820    UP000124542    UP000125968    UP000130610    UP000133348    UP000141212    UP000143912    UP000145152    UP000149516    UP000166143    UP000171773    UP000180363    UP000180364    UP000180365    UP000180366    UP000180367    UP000180368    UP000180370    UP000180371    UP000180372    UP000180373    UP000180374    UP000180375    UP000180377    UP000180378    UP000138593    UP000157984    UP000100289    UP000110240    UP000116351    UP000120111    UP000180409    UP000180410    UP000180411    UP000180412    UP000180413    UP000180414    UP000180415    UP000180416    UP000180417    UP000180418    UP000180419    UP000180420    UP000180421    UP000180422    UP000180423    UP000180424    UP000180425    UP000180426    UP000180427    UP000180428    UP000180429    UP000180430    UP000180431    UP000180432    UP000180433    UP000145008    UP000180383    UP000180384    UP000180385    UP000180386    UP000180387    UP000180388    UP000180389    UP000180390    UP000180391    UP000180393    UP000180394    UP000180395    UP000180396    UP000180397    UP000180398    UP000180399    UP000180400    UP000180401    UP000180402    UP000180403    UP000180404    UP000180405    UP000180406    UP000180407    UP000180408    UP000114004    UP000159535    UP000180376    UP000135071    UP000133987    UP000113286    UP000117687    UP000148533    UP000133546    UP000118579    UP000115935    UP000123303    UP000147828    UP000144273    UP000125082    UP000099142    UP000124386    UP000168969    UP000132037    UP000129608    UP000105365    UP000099158    UP000110133    UP000171533    UP000129563    UP000170944    UP000180369   

PRIDE

P59596   

Pfam

PF01635   Corona_M

Interpro

IPR002574   Corona_M

ProteinModelPortal

E0XIZ6   A0A3S6GSH8   A0A0U1WJY5   R9QTB5   Q3ZTC1   Q4JDQ0   + More
Q4JDR3   Q3ZTD6   Q3ZTE9   A0A2D1PX06   A0A0U1WHK3   Q6RD16   Q6TPE4   Q6T1D8   Q6GYQ7   C4P6R1   Q1EFP1   Q6RD27   Q5DIC1   Q1EFM8   Q3S2C1   Q6RD38   Q6R7Y2   A0A2D1PX75   Q5Y183   Q66VB9   A0A4Y6GMF9   A7J8L8   P59596   Q0QDX6   Q0Q472   Q692E0   Q6QJ38   D5HJS6   D5HJW1   A0A0U1WHJ2   D5HJR5   D5HJX2   D5HJQ4   D5HJZ4   D5HJY3   Q3LZT9   D5HK05   Q3LZV0   Q3LZX9   A0A2D1PX77   D3KDM9   R9QTR4   A0A4Y6GMF2   A0A0K1YZZ2   A0A1W6S797   D2DJW8   A0A0K1Z0P4   A0A2D1PXC4   A0A1W5YKU1   A0A096XNN5   A0A2D1PX60   J9TEG5   A0A4Y6GN43   D5HJT7   Q3I5J2   A0A3G5BIZ3   D2E1F1   D2E1D6   A0A2D1PXF0   U5WL98   U5WIN4   A0A4Y6GN51   A0A0U2PLG3   U5WLC5   A0A2D1PXC6   Q19QW6   A0A3G5BJ07   D2E225   D2E269   F2YKG6   J9TBX8   Q6S8D3   Q1T6X2   B8Q8W3   Q6RD60   Q6VA96   Q6UZF3   Q6VA74   Q6JH42   Q6UZE9   B8Q8V2   Q6RCY3   B8Q8Q7   Q6RD05   Q6JH34   Q6RCX2   Q6VA85   B8Q8R8   Q6RCZ4   Q6RCW1   B8Q8T0   B8Q8U1   Q6V584   D2E210  

PDB

5UTT     E-value=4.67413,     Score=66