Strain

CHINA_AVIAN_2007_NC_016992 (Region: China: Hong Kong;  Strain: Sparrow coronavirus HKU17, complete genome.;  Date: 2007)

Gene

nucleocapsid protein

Description

Annotated in NCBI,  nucleocapsid protein

Location

NC_016992(+):24150-25178

GenBank Accession

YP_005352850.1

Full name

Nucleoprotein      

CDS

ATGGCCACTCCATCAGTACCCACTACTGACGCGTCGTGGTTCCAGGTGCTCAAAGCTCAAAACAAAAAGGCTACTCATCCTCAGTTTCGTGGCAATGGAGTTCCGCTTAACTCTGCCATCAAGCCCGCTGAAAACCATGGCTATTGGCTGCGTTACACCAGACAAAAGCCAGGTGGTACTCAAATTCCTCCATCCTATGCCTTCTATTATACAGGCACAGGTCCGAGAGGAAATCTTAAGTATGGTGAACTCCCTCCTAATGATACCCAGGCAACCACTCGTGTTACTTGGGTTAAGGGTCCGGGAGCAGACACTTCTATTAAGCCTCATGTTGCCAAACGCAACCCCAACAATCCTAAACATCAGCTGCTACCTCTCCGATTTCCAACCGGAGATGGCCCAGCTCAAGGTTTCAGAGTTGACCCCTTCAACGCTAGAGGAAGACCTCAGGAGCGTGGAAGTGGCCCAAGATCTCAATCTGCTAACCCCAGAGGCACTAACAATCAGCCAAGGAAACGCGACCAGTCCGCACCTGCTGCGGTACGTCGTAAGACCCAACATCAAGCTCCCAAGCGGACTTTGCCCAAGGGCAAAACCATCTCTCAGGTATTTGGCAACCGGTCTCGTACTGGCGCCAATGTCGGCTCTGCAGACACTGAGAAGACGGGTATGGCTGATCCTCGCATCATGGCTCTAGCCAGACATGTGCCTGGTGTTCAGGAAATGTTGTTTGCTGGCCACCTCGAGAGCAACTTTCAGGCGGGAGCAATCACCCTGACCTTTTCATACTCAATCACAGTCAAGGAGGGCTCTCCTGACTATGAACGACTAAAGGATGCGCTCAACACTGTGGTCAACCAGACCTATGAGCCTCCAACAAAACCAACTAAGGACAAGAAGCCTGAAAAACAAGACCAGTCTGCAAAACCCAAACAGCAGAAGAAACCCAAAAAGGTGACTCTGCCTGCAGACAAACAGGACTTGGAGTGGGATGATGCTTTTGAGATAAAGCAAGAATCAGCTGCGTAG

Protein

MATPSVPTTDASWFQVLKAQNKKATHPQFRGNGVPLNSAIKPAENHGYWLRYTRQKPGGTQIPPSYAFYYTGTGPRGNLKYGELPPNDTQATTRVTWVKGPGADTSIKPHVAKRNPNNPKHQLLPLRFPTGDGPAQGFRVDPFNARGRPQERGSGPRSQSANPRGTNNQPRKRDQSAPAAVRRKTQHQAPKRTLPKGKTISQVFGNRSRTGANVGSADTEKTGMADPRIMALARHVPGVQEMLFAGHLESNFQAGAITLTFSYSITVKEGSPDYERLKDALNTVVNQTYEPPTKPTKDKKPEKQDQSAKPKQQKKPKKVTLPADKQDLEWDDAFEIKQESAA

Function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.

Uniprot

H9BR04   A0A2H5CUI5   A0A145YPD2   A0A141ZUW2   A6N256   H9BQY9   + More
A0A141ZUZ3   A0A2H5A4I6   X2EXX6   A0A075E3D3   A0A075E3K6   A0A097EU39   A0A075E3J0   A0A1L3HEF1   A0A218PFD5   A0A1J0F3T0   A0A1Z4F682   H9BQY2   A0A0E3N3M9   A0A1V0K0R5   A0A222YTQ4   A0A1V0K0Q9   A0A060A850   A0A346JFE5   A0A1P8VJV9   A0A140ESE1   A0A0E3Y4M2   A0A075X152   A0A060A4F5   A0A191Z552   A0A172PY73   A0A140ES57   A0A172PY74   A0A0D5Z9E4   A0A1V0K0S6   A0A172PY72   A0A0K0PUY6   A0A2R4Q8U8   A0A1V0K0R8   A0A172PY66   A0A223DMX2   A0A343ERD2   A0A140ESG9   A0A1P8JPU1   A0A1S6K7S4   A0A1J0F4N6   A0A0M4KLU8   A0A191TBX5   A0A4P8FBU5   A0A3Q8TDL8   A0A075E3L1   W8QHP7   A0A222YWH3   A0A2Z4EVY3   A0A1D9CJT9   A0A2Z4EVW1   A0A2Z4EVX0   A0A161CGH2   A0A1S6KJP5   A0A1S6KJP7   A0A161CMH4   A0A2Z4G611   A0A2Z4G5Z1   A0A2Z4G610   A0A2Z5XXV0   A0A2Z5XXV3   A0A2Z4G614   A0A346IMW6   B6VDY2   B6VDZ1   H9BR12   H9BQZ6   A0A2Z5XXS5   A0A2Z5XXU0   A0A2Z5XXQ6   A0A5B8KGZ7   B6VDW4   B6VDX3  

Pubmed

22278237    27424024    27231358    27718337    26982324    17459938    + More
24723718    28634353    24964136    25153521    24744332    26584185    26250097    25817405    28345292    29621617    29695146    29569144    25759498    25740769    26337879    28758347    26514769    24723704    29872066    27496131    29363281    30758768    18971277    31239538   

EMBL

JQ065045    AFD29213.1    MF041982    MG242062    AUH28254.1    AVZ61086.1    + More
KU984334    KX118627    KU870485    KU870486    KU870488    AMW88201.1    AOM53031.1    APC23087.1    APC23088.1    APC23090.1    KU051641    KU051642    KU051643    KU051644    KU051645    KU051646    KU051647    KU051648    KU051649    KU051650    KU051651    KU051653    KU051654    KU051655    KU051656    AMN91625.1    AMN91631.1    AMN91637.1    AMN91643.1    AMN91649.1    AMN91655.1    AMN91661.1    AMN91667.1    AMN91674.1    AMN91680.1    AMN91686.1    AMN91698.1    AMN91704.1    AMN91710.1    AMN91716.1    EF584908    ABQ39962.1    JQ065043    AFD29198.1    KU051652    AMN91692.1    KY513725    AUG59168.1    KJ567050    AHM88404.1    KJ601778    AIB07797.1    KJ601777    AIB07789.1    KM820765    AIT11904.1    KJ601780    AIB07811.1    KY065120    APG38202.1    LC260045    BAZ95613.1    KU870487    APC23089.1    LC216914    LC216915    BAY00727.1    BAY00734.1    JQ065042    KJ462462    KJ569769    KJ584355    KJ584357    KJ584358    KJ584360    KJ620016    KM012168    KT381613    AFD29191.1    AHN16224.1    AHN16231.1    AIA60977.1    AIA60991.1    AIA60998.1    AIA61011.1    AIA99522.1    AIP90490.1    ALJ32189.1    KP981395    KP757891    KP757892    KR131621    KT336560    KR150443    KR265849    KR265850    KR265851    KR265852    KR265853    KR265854    KR265855    KR265856    KR265857    KR265858    KR265859    KR265865    KU665558    KU981059    KU981060    KU981061    KU981062    KY354363    KY354364    KY078891    KY078897    KY078898    KY078903    KY364365    KY293677    KX710203    KX710204    MF095123    KY398010    KY513724    MG837130    MG837131    MG837132    MG837133    MG832584    MH715491    LC260038    LC260039    LC260040    LC260041    LC260042    LC260043    LC260044    MK211169    MK355396    MK572803    MK330604    AKA97942.1    AKC54439.1    AKC54446.1    ALA13749.1    ALS54090.1    AML40608.1    AML40794.1    AML40801.1    AML40808.1    AML40815.1    AML40822.1    AML40829.1    AML40836.1    AML40843.1    AML40850.1    AML40857.1    AML40864.1    AML40906.1    AML83920.1    ANA78447.1    AQT34133.1    AQT34139.1    ARD25154.1    ARD25160.1    ARD25161.1    ARD25166.1    ARJ31778.1    ASK86338.1    ASW22235.1    ASW22236.1    ASY98690.1    ATU88974.2    AUG59160.1    AWG96869.1    AWG96876.1    AWG96882.1    AWG96888.1    AYP31076.1    AYU65238.1    BBA66309.1    BBA66316.1    BBA66323.1    BBA66330.1    BBA66337.1    BBA66344.1    BBA66351.1    QDF21514.1    QDH76192.1    QDH76197.1    QDP14515.1    KY078895    KY363868    ARD25158.1    ATV90805.1    MF431743    ASR75150.1    KY078894    KY078896    MF280390    ARD25157.1    ARD25159.1    AVR48523.1    KJ584359    AIA61005.1    MH708123    MH708124    MH708125    AXP32220.1    AXP32227.1    AXP32234.1    KX834351    KX834352    KY078893    KY078901    KY363867    APZ76694.1    APZ76702.1    ARD25156.1    ARD25164.1    ATV90794.1    KR265860    KR265861    AML40871.1    AML40878.1    KP757890    AKC54432.1    KJ769231    AIH06861.1    KJ584356    AIA60984.1    KX083667    ANJ61325.1    KU204700    AND74256.1    KR265847    KR265848    AML40780.1    AML40787.1    KU204701    KY078892    AND74257.1    ARD25155.1    KP995363    KP995364    KP995365    KP995366    KP995367    KP995368    KP995369    KT371504    KT371505    KT371506    KT371507    KR265862    KR265863    KT945051    KU870489    AKA42991.1    AKA42993.1    AKA42994.1    AKA42995.1    AKA42996.1    ALZ48523.1    ALZ48526.1    AML40885.1    AML40892.1    AMW02953.1    APC23091.1    KY078902    ARD25165.1    KU204699    AND74255.1    KT266822    AKQ63087.1    MG738720    AVY03266.1    KY078899    KY078900    ARD25162.1    ARD25163.1    KU204698    AND74254.1    KY926512    ASS83090.1    KY293678    ASK86345.1    KR265864    AML40899.1    KY129986    MF948005    APW35737.1    ATJ00133.1    KX443143    AQS99157.1    KU870490    APC23092.1    KT021234    ALD83760.1    KX022602    KX022603    KX022604    KX022605    ANI85829.1    ANI85836.1    ANI85843.1    ANI85850.1    MK005882    MK330605    QCO76967.1    QDP14522.1    MG897688    AZL30771.1    KJ601779    AIB07804.1    KJ481931    AHL45011.1    MF431742    ASR75143.1    MG812378    AWV67138.1    KX534091    AOY36530.1    MG812375    MG812376    AWV67111.1    AWV67120.1    MG812377    AWV67129.1    KR060085    ALL74103.1    KY586147    KY586148    AQT03441.1    AQT03443.1    KY586149    AQT03445.1    KR060084    ALL74102.1    MF642323    AWV96570.1    MF642322    AWV96563.1    MF642324    AWV96577.1    LC364345    BBC54856.1    LC364346    BBC54865.1    MF642325    AWV96584.1    MH532440    AXP20285.1    FJ376621    ACJ12057.1    FJ376622    ACJ12066.1    JQ065046    AFD29221.1    JQ065044    AFD29205.1    LC364343    BBC54836.1    LC364344    BBC54846.1    LC364342    BBC54826.1    MK204388    QDY92325.1    FJ376619    ACJ12039.1    FJ376620    ACJ12048.1   

Proteomes

UP000142997    UP000112854    UP000108307    UP000141273    UP000103330    UP000126862    + More
UP000129252    UP000160089    UP000114014    UP000172095    UP000103266    UP000122701    UP000124223    UP000149778    UP000152486    UP000152859    UP000156755    UP000161942    UP000174689    UP000115701    UP000116882    UP000118503    UP000120336    UP000130144    UP000131750    UP000136494    UP000144892    UP000147360    UP000150502    UP000151351    UP000154045    UP000156468    UP000158884    UP000162784    UP000163421    UP000169372    UP000170248    UP000171091    UP000180351    UP000180352    UP000147537    UP000117737    UP000137853    UP000172024    UP000139576    UP000118543    UP000097413    UP000148151    UP000132517    UP000161041    UP000100106    UP000118624    UP000120804    UP000104403    UP000102644    UP000011786    UP000103579    UP000162232    UP000135406    UP000161619    UP000116644   

Pfam

PF00937   Corona_nucleoca

Interpro

IPR037179   Nucleocapsid_C
IPR001218   Corona_nucleocap
IPR037195   Nucleocapsid_N

SUPFAM

SSF110304   SSF110304
SSF103068   SSF103068

ProteinModelPortal

H9BR04   A0A2H5CUI5   A0A145YPD2   A0A141ZUW2   A6N256   H9BQY9   + More
A0A141ZUZ3   A0A2H5A4I6   X2EXX6   A0A075E3D3   A0A075E3K6   A0A097EU39   A0A075E3J0   A0A1L3HEF1   A0A218PFD5   A0A1J0F3T0   A0A1Z4F682   H9BQY2   A0A0E3N3M9   A0A1V0K0R5   A0A222YTQ4   A0A1V0K0Q9   A0A060A850   A0A346JFE5   A0A1P8VJV9   A0A140ESE1   A0A0E3Y4M2   A0A075X152   A0A060A4F5   A0A191Z552   A0A172PY73   A0A140ES57   A0A172PY74   A0A0D5Z9E4   A0A1V0K0S6   A0A172PY72   A0A0K0PUY6   A0A2R4Q8U8   A0A1V0K0R8   A0A172PY66   A0A223DMX2   A0A343ERD2   A0A140ESG9   A0A1P8JPU1   A0A1S6K7S4   A0A1J0F4N6   A0A0M4KLU8   A0A191TBX5   A0A4P8FBU5   A0A3Q8TDL8   A0A075E3L1   W8QHP7   A0A222YWH3   A0A2Z4EVY3   A0A1D9CJT9   A0A2Z4EVW1   A0A2Z4EVX0   A0A161CGH2   A0A1S6KJP5   A0A1S6KJP7   A0A161CMH4   A0A2Z4G611   A0A2Z4G5Z1   A0A2Z4G610   A0A2Z5XXV0   A0A2Z5XXV3   A0A2Z4G614   A0A346IMW6   B6VDY2   B6VDZ1   H9BR12   H9BQZ6   A0A2Z5XXS5   A0A2Z5XXU0   A0A2Z5XXQ6   A0A5B8KGZ7   B6VDW4   B6VDX3  

PDB

2C86     E-value=3.80525e-18,     Score=224