Strain

USA_MURINE_1998_NC_023760 (Region: USA: Wisconsin;  Strain: Mink coronavirus strain WD1127, complete genome.;  Date: 1998)

Gene

non-structural protein 3c

Description

Annotated in NCBI,  non-structural protein 3c

Location

NC_023760(+):24656-25399

GenBank Accession

YP_009019183.1

Full name

Non-structural protein 3b       + More
Putative non-structural protein 3b      

Alternative Name

Accessory protein 3b
Protein X2
Non-structural protein 3-1
X2b protein

CDS

ATGATAGGTAGTCTCATTACCGGTTTGTTTATAACATCTATTTCGTTTTTAAAGGAAGATGTTACCATTAAAACTACAGATGTCCAAGCAGACACTAATTGTAGTACTATTGTGCAGCGCTCTGTCGCCGCACCTAAAAGTTACACAGATGATGTTTCTGTGTTTATTATTTCTTTATTGTTTTCTATATTTTTGGCTATGTACCGTAGTACAAGCTTTAAATCAAATGTAGCTCTGTCTCTGTTTAAGATTGCTACTATTTGTTTCATATCACCATTCCTTATAGGTTTAGGTCTATATGTTGATGGTATTGTTACGTTAGTGGTACTCTTAAGTCGCTACTTTTATTTGAGTTACTTTTGGTTTAAGTTTGAACGTTTTGAATTTTTATTCTACAATGTTTCAACTTTAATGTTTGTACATGGTAAAGCTGCACCGTATTTGAGAAGTTCTAATCACGCTCATTATGTGACACTTTATGGTAGTCTTAATCATATGAGAGTGGATGACTTTACGTTGTACTTTGTAGACCCAATGCTAGTTAAAATAGCAATTAGAGGCTTTGTTCAATTAGATCTTAATGTTGTAAGGTCTATAGAACTTCTTAACGGTGATTTTATTTACATATTTTCACCAGAGCCTGTTGTTGGTGTTTATAATGCAGCGTTTTCTCAAGACATTGTAAACGAAATTAAATTAGACGATCATAGTTATGAGATTCCCGAACGTCTTGACTGTGATTGA

Protein

MIGSLITGLFITSISFLKEDVTIKTTDVQADTNCSTIVQRSVAAPKSYTDDVSVFIISLLFSIFLAMYRSTSFKSNVALSLFKIATICFISPFLIGLGLYVDGIVTLVVLLSRYFYLSYFWFKFERFEFLFYNVSTLMFVHGKAAPYLRSSNHAHYVTLYGSLNHMRVDDFTLYFVDPMLVKIAIRGFVQLDLNVVRSIELLNGDFIYIFSPEPVVGVYNAAFSQDIVNEIKLDDHSYEIPERLDCD

Similarity

Belongs to the coronaviruses NS3b protein family.

Keywords

Host membrane   Membrane   Transmembrane   Transmembrane helix   Reference proteome  

Feature

chain  Non-structural protein 3b

Uniprot

D9J1Z5   A0A222UC37   A0A222UBX8   D3XGJ5   A0A172AZB2   D3YGU6   + More
A0A1B4X970   A0A224ANW5   D3YGU5   A0A0K2SF38   H9TEX3   D2WXM0   F6M1R2   Q5VJT9   A0A0K2BMQ8   E7E029   Q7T6T1   B7T4B1   B7T064   I0B0R3   Q0ZVX3   E7E038   G8J7G7   Q5VJU5   B7T4C0   H9TEW4   S6BUL5   B7T074   Q0PL02   Q1W2P0   A0A1S6KDU9   P09047   Q0PKZ3   G3CI06   V9IMK5   V9IMT5   A0A0U2U3A1   A0A077ERP6   A0A1Y0AXV1   D1LT74   D1LT49   A0A077EV34   C0LLP5   T1STP8   V9ILT6   A0A1D8ELQ9   A0A0C5CJG0   V9IMT0   A0A1Z2WU98   D1LT59   C6GHA9   A0A088NDD8   A0A2Z6FAA5   D1LT68   A0A2H5BX15   A0A2H4KI10   V9IMK2   A0A2Z6FAB3   G1FEY9   V9ILW1   A0A077EV74   A0A2Z6FA98   A0A2H4KI32   D1LT76   C0LLN1   A0A088NDC7   D1LT54   D3KDL7   D3KDK6   A0A2Z6FAC2   D1LT70   V9ILU5   Q9YRA6   A0A077EVA2   D1LT79   A0A077ER27   D1LT50   D1LT82   E0AH00   D1LT52   A0A077EV84   D1LT57   A0A077EVB0   A0A077ER66   A0A2Z6FAD3   Q85084   A0A2Z6FAB4   Q88512   A0A1X9Y2H9   A0A077ER53   A0A077ERN3   D1LT58   V9IMT7   Q0PL28   C0LLN8   D1LT66   V9ILU1   C6GHI1   D1LT56   A0A077EXD9  

Pubmed

21346029    20079778    22002680    26221765    21481551    15177889    + More
19036814    25953186    22438554    16704791    17275120    22609354    25180686    17023013    2825819    2548340    2549745    10805807    23043168    25890036    25150756    19889934    27619563    25667330    29769478    10365166    7707547    8546012    20229183    26822958   

EMBL

HM245925    ADI80514.1    KX512810    ASR18947.1    KX512809    ASR18939.1    + More
GU338457    ADD49359.1    KM347965    AKG92641.1    GU459060    ADD26776.1    LC119077    BAV31350.1    LC215871    BBA21169.1    GU459059    ADD26775.1    LC029419    BAS25711.1    JQ404410    KY063616    AFG19741.1    ASB15741.1    GQ477367    ADB28910.1    JF682842    AEE69325.1    AY426984    AAR88621.1    KP849472    AKZ66474.1    HQ450376    ADU17728.1    AY342160    EU924790    ACJ64178.1    EU856361    KP981644    ACJ63234.1    AKA65832.1    JQ408980    AFH55114.1    DQ112226    AAZ91439.1    HQ450377    ADU17737.1    JN856008    AEQ61970.1    AY426983    AAR88615.1    EU924791    ACJ64187.1    JQ404409    AFG19732.1    AB781789    BAN67912.1    EU856362    ACJ63245.1    DQ811788    ABG89326.1    DQ443743    ABD97837.1    HQ462571    KP202848    KX499468    KX900393    KX900394    KX900402    ADY39742.1    AKA60056.1    AQT01351.1    ASV64279.1    ASV64288.1    ASV64360.1    X06371    X12800    AJ271965    DQ811789    ABG89332.1    HM776941    KC962433    KU729220    AEM55568.1    AGM75128.1    AML22778.1    JQ304287    AEY69252.1    JQ304285    AEY69251.1    KR061459    ALR84921.1    KJ665822    AIL54149.1    KX532152    ART29867.1    GU053633    ACY69062.1    GU053608    JQ304289    ACY69037.1    AEY69254.1    KJ665819    AIL54140.1    FJ718992    ACN79559.1    KF530123    AGT52083.1    JQ304281    AEY69248.1    KX689261    AOT21921.1    KP143509    KP143510    KP143511    AJO26996.1    AJO27006.1    AJO27016.1    JQ304279    AEY69246.1    KY292377    ASB16890.1    GU053618    ACY69047.1    FJ938053    ACT10879.1    KJ879420    KJ879424    KJ879425    KJ879427    AIN55964.1    AIN55976.1    AIN55979.1    AIN55985.1    LC316060    BBE15201.1    GU053627    ACY69056.1    KY566209    KY566210    KY566211    AUG98122.1    AUG98133.1    AUG98144.1    KX722529    ASU62491.1    JQ304280    AEY69247.1    LC316074    BBE15213.1    JN183883    AEK25524.1    JQ304278    AEY69245.1    KJ665816    KJ665818    AIL54131.1    AIL54137.1    LC316054    LC316055    LC316056    LC316057    LC316058    BBE15195.1    BBE15196.1    BBE15197.1    BBE15198.1    BBE15199.1    KX722530    ASU62502.1    GU053635    ACY69064.1    FJ718988    ACN79545.1    KJ879419    AIN55961.1    GU053613    ACY69042.1    GU553362    ADC35475.1    GU553361    ADC35464.1    LC316083    BBE15221.1    GU053629    GU053631    ACY69058.1    ACY69060.1    JQ304273    AEY69240.1    AF104420    AAC96005.1    KJ665831    AIL54176.1    GU053638    ACY69067.1    KJ665815    AIL54128.1    GU053609    ACY69038.1    GU053644    ACY69070.1    HQ012372    ADL71500.1    GU053611    GU053634    JQ304274    JQ304275    ACY69040.1    ACY69063.1    AEY69241.1    AEY69242.1    KJ665821    AIL54146.1    GU053616    ACY69045.1    KJ665836    AIL54191.1    KJ665830    AIL54173.1    LC316103    BBE15240.1    U26210    AAA67951.1    LC316072    BBE15211.1    Z35758    CAA84808.1    KX527917    ARS22396.1    KJ665824    KJ665825    KJ665827    KJ665828    KJ665838    AIL54155.1    AIL54158.1    AIL54164.1    AIL54167.1    AIL54197.1    KJ665817    AIL54134.1    GU053617    ACY69046.1    JQ304293    AEY69256.1    DQ811785    ABG89294.1    FJ755618    FJ718990    JX013850    ACN71198.1    ACN79552.1    AFN88474.1    GU053625    ACY69054.1    JQ304288    AEY69253.1    FJ938060    ACT10951.1    GU053615    KU215419    KU215420    KU215421    KU215422    KU215423    KU215424    KU215425    KU215426    KU215427    KU215428    ACY69044.1    AMD11133.1    AMD11145.1    AMD11156.1    AMD11167.1    AMD11178.1    AMD11189.1    AMD11200.1    AMD11211.1    AMD11222.1    AMD11233.1    KJ665823    AIL54152.1   

Proteomes

UP000156811    UP000150460    UP000272061    UP000106470    UP000129066    UP000174600    + More
UP000115330    UP000096172    UP000153699    UP000119169    UP000137024    UP000158504    UP000098772    UP000113525    UP000001440    UP000158285    UP000123026    UP000131894    UP000166047    UP000125818    UP000113324    UP000100168    UP000105943    UP000140032    UP000123646    UP000173564    UP000138585    UP000137357    UP000110620    UP000145148    UP000111647    UP000118118    UP000102801    UP000113596    UP000117806    UP000125896    UP000126919    UP000135072    UP000135717    UP000143834    UP000158395    UP000161862   

PRIDE

P09047   

Pfam

PF03053   Corona_NS3b

Interpro

IPR004293   Coronavirus_Orf3b

ProteinModelPortal

D9J1Z5   A0A222UC37   A0A222UBX8   D3XGJ5   A0A172AZB2   D3YGU6   + More
A0A1B4X970   A0A224ANW5   D3YGU5   A0A0K2SF38   H9TEX3   D2WXM0   F6M1R2   Q5VJT9   A0A0K2BMQ8   E7E029   Q7T6T1   B7T4B1   B7T064   I0B0R3   Q0ZVX3   E7E038   G8J7G7   Q5VJU5   B7T4C0   H9TEW4   S6BUL5   B7T074   Q0PL02   Q1W2P0   A0A1S6KDU9   P09047   Q0PKZ3   G3CI06   V9IMK5   V9IMT5   A0A0U2U3A1   A0A077ERP6   A0A1Y0AXV1   D1LT74   D1LT49   A0A077EV34   C0LLP5   T1STP8   V9ILT6   A0A1D8ELQ9   A0A0C5CJG0   V9IMT0   A0A1Z2WU98   D1LT59   C6GHA9   A0A088NDD8   A0A2Z6FAA5   D1LT68   A0A2H5BX15   A0A2H4KI10   V9IMK2   A0A2Z6FAB3   G1FEY9   V9ILW1   A0A077EV74   A0A2Z6FA98   A0A2H4KI32   D1LT76   C0LLN1   A0A088NDC7   D1LT54   D3KDL7   D3KDK6   A0A2Z6FAC2   D1LT70   V9ILU5   Q9YRA6   A0A077EVA2   D1LT79   A0A077ER27   D1LT50   D1LT82   E0AH00   D1LT52   A0A077EV84   D1LT57   A0A077EVB0   A0A077ER66   A0A2Z6FAD3   Q85084   A0A2Z6FAB4   Q88512   A0A1X9Y2H9   A0A077ER53   A0A077ERN3   D1LT58   V9IMT7   Q0PL28   C0LLN8   D1LT66   V9ILU1   C6GHI1   D1LT56   A0A077EXD9  

KEGG

vg:18585630     vg:27963645     vg:26626390    

GO

GO:0016021  C:integral component of membrane
GO:0033644  C:host cell membrane

From MSLVP

Multi-Pass Membrane

From Uniprot

Host membrane  

Length:

247

Number of predicted TMHs:

3

Exp number of AAs in TMHs:

68.0393099999999

Exp number, first 60 AAs:

9.6438

Total prob of N-in:

0.10698

outside

1  -  51

TMhelix

52  -  70

inside

71  -  76

TMhelix

77  -  99

outside

100  -  102

TMhelix

103  -  122

inside

123  -  247