Strain

NETHERLAND_FERRET_2010_NC_030292 (Region: Netherlands;  Strain: Ferret coronavirus isolate FRCoV-NL-2010, complete genome.;  Date: 2010)

Gene

membrane protein

Description

Annotated in NCBI,  membrane protein

Location

NC_030292(+):25448-26245

GenBank Accession

YP_009256200.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGATAGAGATAGTACTATTAGTTTGTTCTGCTATAGCAGCTATGGTTCCAACCACTGCTGCTAGTGGTAATCGCTATTGCTTAGTAAACAATACCGAAGGTGCCACACAGAATTGTTCTATTAATGATTGCATTGATGAGGGAAGTCTTATTTGGCATCTTATGAACTGGAGCTTCAGCTGGTCTGTGGTTTTAATTGTTTTTATTGCAATTTTGCAATATGGCAGACCGCAGTTCAGCTGGTTCATGTATGGGGTTAAAATGTTAATCATGTGGCTTTTATGGCCTCTTGTTTTAGCGCTCACGATTTTTAATGCCTATGCTGAATTTAAAAGTTCTAGATATGTAATGTTTGGCTTTAGCGTATCTGGTGCCATGGTCACATTGGTTATGTGGATTATGTATTTTGCAAGATCTATCCAATTATGGCGTCGTACCAGAACATGGTGGTCTTTCAACCCTGAGACTAACGCTATACTTTGTCTCAGTTCGGTAGGAAAGAGATTTGTTTTACCATTGAGTGGTGCTCCTACTGGTGTGACACTAACTTTGCTTTCTGGCAATTTATATGCTGAGGGTTTTAAAGTTGGAAGTGGTGTCAATGTTGACAATCTACCAAAATACATCATGGTGGCCACACCTGGTAATACAATTGTGTACCATCAGGTTGGAAAATCATTGAAAGCATCGAGTGCGACTGGATGGTCGTACTATGTCAGAGCTAAAGCTGGCGATTACTCAACAGAAGCAAGACATGACAATTTGAGTGAACATGAAAAATTATTACATATGGTATAA

Protein

MIEIVLLVCSAIAAMVPTTAASGNRYCLVNNTEGATQNCSINDCIDEGSLIWHLMNWSFSWSVVLIVFIAILQYGRPQFSWFMYGVKMLIMWLLWPLVLALTIFNAYAEFKSSRYVMFGFSVSGAMVTLVMWIMYFARSIQLWRRTRTWWSFNPETNAILCLSSVGKRFVLPLSGAPTGVTLTLLSGNLYAEGFKVGSGVNVDNLPKYIMVATPGNTIVYHQVGKSLKASSATGWSYYVRAKAGDYSTEARHDNLSEHEKLLHMV

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.

Similarity

Belongs to the alphacoronaviruses M protein family.

Keywords

Glycoprotein   Host Golgi apparatus   Host membrane   Membrane   Transmembrane   Transmembrane helix   Viral envelope protein   Viral matrix protein   Virion   Reference proteome  

Feature

chain  Membrane protein

Uniprot

A0A172B6J4   A0A222UC68   A0A1B4X968   A0A224ANT6   D3XGJ7   A0A0K2SF30   + More
A0A222UBY5   D3XGI9   D9J206   A0A2R4QKX9   D9J1Z7   A0A384V9E4   A0A384V9Q6   A0A384V9L3   A0A384V9R1   A0A384VA81   G8J7G9   A0A3S6JCJ2   Q0PL09   A0A384VIC0   F6M1R4   A0A384V9G9   A0A384VGP5   Q80RP1   A0A0U2TVR6   Q6TPL0   M4I7F5   Q5FX57   Q64FR0   G8A505   M4I7F1   H9TEW2   B7T4B3   Q0PKZ1   A0A0Y0R0E2   Q0PL26   U3Q0B8   Q6PQ04   A0A0D5ZYB2   Q5DQ89   A0A0K2BMP6   A0A0E3GM58   Q5FX58   A7UJ02   A0A514KFM3   B7T076   B7T066   Q9DY23   Q6T524   S6B903   A0A1L7NS55   P33464   Q6TPL1   Q0PL00   F1CNZ1   P04135   C0J8Y5   A0A1D8ELQ6   M4I824   D2WXM2   Q0ZVX1   Q1W2N8   A0A1S6KDW8   Q7T6S9   Q7T713   R9RZN0   Q5G1S6   Q5G1S5   G3CI08   C0J8Y6   Q64FQ9   A0A0K1RM39   A0A514KFL3   A0A514KHD6   A0A514KH02   Q9WKM6   A0A514KFJ5   A0A514KFK4   I3QKR3   P24412   E7E031   Q88514   Q19NU4   Q5D578   H9TEX6   A0A514KFJ6   D6RTP4   A0A514KFK5   A0A514KFJ4   A0A514KFJ0   A0A514KFK1   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   A0A1L6BQB0   A0A2H4KI18   Q8JVR1   A0A514KFL5   C6K2U0  

Pubmed

20079778    21346029    22609354    17023013    22002680    12505636    + More
18306032    22542271    19036814    21481551    25953186    26221765    20229183    25180686    27840394    1662846    2841792    3035066    2825819    10805807    3008432    11152504    1309909    7636969    19162099    27619563    16704791    17275120    15177889    25890036    23043168    26250391    10365166    2174956    8546012    22718568    8839428    20603153   

EMBL

KM347965    AKG92643.1    KX512809    ASR18941.1    LC119077    BAV31352.1    + More
LC215871    BBA21171.1    GU338457    ADD49361.1    LC029419    BAS25713.1    KX512810    ASR18949.1    GU338456    ADD49352.1    HM245926    ADI80525.1    MF113046    AVY53338.1    HM245925    ADI80516.1    KX900395    ASV64299.1    KX900396    KX900399    KX900400    KX900401    KX900403    KX900405    KX900406    KX900407    ASV64308.1    ASV64335.1    ASV64343.1    ASV64353.1    ASV64371.1    ASV64388.1    ASV64397.1    ASV64406.1    KX900404    ASV64379.1    KX900408    KX900409    ASV64415.1    ASV64424.1    KX900397    ASV64317.1    JN856008    AEQ61972.1    KY406735    ASV45152.1    DQ811787    ABG89312.1    KX900411    ASV64442.1    JF682842    AEE69327.1    KX900398    ASV64326.1    KX900410    ASV64433.1    AF502583    AAO33711.1    KR061459    ALR84918.1    AY390344    AAQ96368.1    JQ693055    AFZ88850.1    AY884049    KC175340    KC175341    AAW57899.1    AFX81102.1    AFX81112.1    AY704916    AAU29609.1    GU146061    ADB10854.1    JQ693056    AFZ88851.1    JQ404409    AFG19730.1    EU924790    EU924791    HQ450377    ACJ64180.1    ACJ64189.1    ADU17739.1    DQ811789    ABG89329.1    KT696544    AMB66492.1    DQ811785    ABG89300.1    KF273109    AGW80452.1    AY587883    AAT00646.1    KP981644    AKA65834.1    AY548235    AAT45197.1    KP849472    AKZ66477.1    KP202848    AKA60058.1    AY884048    AAW57898.1    EU074218    FJ755618    ABU49663.1    ACN71200.1    MK986745    QDI78404.1    EU856362    ACJ63247.1    EU856361    ACJ63236.1    AF302262    AAG30226.1    AY436635    AAR11075.1    AB781790    BAN67923.1    LC190907    BAW32707.1    X55980    X60056    AY390343    AAQ96367.1    DQ811788    ABG89323.1    HQ462571    ADY39744.1    M21627    X05598    X06371    AJ271965    M14878    FJ009114    ACN60154.1    KX689261    AOT21923.1    JQ693053    AFZ88848.1    GQ477367    ADB28912.1    DQ112226    AAZ91441.1    DQ443743    ABD97839.1    JQ693054    KU729220    KX499468    KX900393    KX900394    KX900402    MK166015    AFZ88849.1    AML22781.1    AQT01353.1    ASV64281.1    ASV64290.1    ASV64362.1    QCZ41128.1    AY342160    AY335549    DQ201447    AAQ02626.1    ABC72418.1    KC962433    AGM75130.1    AY864661    AAW66660.1    AY864662    AAW66661.1    HM776941    AEM55570.1    FJ009115    ACN60155.1    AY704917    AAU29610.1    KR270796    AKV62759.1    MK986735    QDI78394.1    MK986732    QDI78391.1    MK986736    QDI78395.1    AF104420    AAC96007.1    MK986733    QDI78392.1    MK986734    QDI78393.1    JQ700303    AFK10485.1    Z24675    HQ450376    ADU17730.1    Z35758    CAA84810.1    DQ517438    ABF72147.1    AY899209    AAX18705.1    JQ404410    KY063616    KY063617    KY063618    AFG19744.1    ASB15743.1    ASB15753.1    ASB15761.1    MK986737    QDI78396.1    AB535528    BAJ08260.1    MK986731    QDI78390.1    MK986730    QDI78389.1    MK986738    QDI78397.1    MK986743    QDI78402.1    MK986742    QDI78401.1    MK986746    QDI78405.1    MK986739    QDI78398.1    MK986741    QDI78400.1    KX083668    APQ31246.1    KX722529    ASU62493.1    AB086903    BAC01158.1    MK986744    QDI78403.1    GQ152141    ACS44222.1   

Proteomes

UP000150460    UP000272061    UP000132946    UP000156811    UP000153699    UP000149523    + More
UP000125818    UP000155481    UP000165378    UP000119169    UP000158285    UP000166023    UP000145148    UP000115330    UP000174600    UP000098772    UP000111647    UP000121388    UP000137024    UP000113525    UP000001440    UP000129066    UP000158504    UP000131894    UP000156732    UP000123026    UP000166047    UP000129150    UP000106470    UP000164750   

PRIDE

P33464    P04135    Q7T6S9    P24412   

Pfam

PF01635   Corona_M

Interpro

IPR002574   Corona_M
IPR042551   ALPHA_CORONA_M

ProteinModelPortal

A0A172B6J4   A0A222UC68   A0A1B4X968   A0A224ANT6   D3XGJ7   A0A0K2SF30   + More
A0A222UBY5   D3XGI9   D9J206   A0A2R4QKX9   D9J1Z7   A0A384V9E4   A0A384V9Q6   A0A384V9L3   A0A384V9R1   A0A384VA81   G8J7G9   A0A3S6JCJ2   Q0PL09   A0A384VIC0   F6M1R4   A0A384V9G9   A0A384VGP5   Q80RP1   A0A0U2TVR6   Q6TPL0   M4I7F5   Q5FX57   Q64FR0   G8A505   M4I7F1   H9TEW2   B7T4B3   Q0PKZ1   A0A0Y0R0E2   Q0PL26   U3Q0B8   Q6PQ04   A0A0D5ZYB2   Q5DQ89   A0A0K2BMP6   A0A0E3GM58   Q5FX58   A7UJ02   A0A514KFM3   B7T076   B7T066   Q9DY23   Q6T524   S6B903   A0A1L7NS55   P33464   Q6TPL1   Q0PL00   F1CNZ1   P04135   C0J8Y5   A0A1D8ELQ6   M4I824   D2WXM2   Q0ZVX1   Q1W2N8   A0A1S6KDW8   Q7T6S9   Q7T713   R9RZN0   Q5G1S6   Q5G1S5   G3CI08   C0J8Y6   Q64FQ9   A0A0K1RM39   A0A514KFL3   A0A514KHD6   A0A514KH02   Q9WKM6   A0A514KFJ5   A0A514KFK4   I3QKR3   P24412   E7E031   Q88514   Q19NU4   Q5D578   H9TEX6   A0A514KFJ6   D6RTP4   A0A514KFK5   A0A514KFJ4   A0A514KFJ0   A0A514KFK1   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   A0A1L6BQB0   A0A2H4KI18   Q8JVR1   A0A514KFL5   C6K2U0  

PDB

4FBH     E-value=2.45071,     Score=69