Strain

CHINA_MURINE_2013_NC_032730 (Region: China;  Strain: Lucheng Rn rat coronavirus isolate Lucheng-19, complete genome.;  Date: 2013)

Gene

nucleocapsid protein

Description

Annotated in NCBI,  nucleocapsid protein

Location

NC_032730(+):26974-28149

GenBank Accession

YP_009336487.1

Full name

Nucleoprotein      

CDS

ATGAGTTCTAATGTCTCCTGGGCCGACCAAGTTGAAACCGTCAACAGACGCCAACGTTCTCGCTCCAGAGGCAGATCTCAAAACAGAACCAATGCTTCGAATCCGTTGTCTTGGTTTACCTCAATCATTGATGAGTCTAATGGAAACTTCATTAGTCTTATGCCTCATAGTGGTGTACCTACTGGTATGGGCACTGCAGCTCAGCAGTGTGGTTACTGGTATCGTGCACCAACCGTCTATCAGGTGCGCCGCGGTAAGAGAGTACCTCTACCTCCTGTATGGTACTTCTACTTTCTGGGTACTGGTCCTCATGCTAATGCCGCTTACGGAACAGCAATGGACGGAGTCTTCTGGGTTAAGACGAAAAATGGTCAGATTGACCCTAAGTCTACTAAAGCTCTTGGTGTACGTGACAGTGGTACAGATCCTAGGCGCGCTAACATACCTAACCTTCCTGAAGGGCTGCGTGTGAACGTTCCTAATGCTTCTAGACCACAGTCTCGCGCTCAGTCTCAGACTAGATCGCAGAATACTTCACGTGCATCCTCTGTCAGCAGAAACGGCTCCAGAGCTCCTAGTGTTGATAGAACTAAAGAAGACCTCAAAGCAGTTGTTTCACAGCTCCTTGCGGAGATGGGTATAAGTAAAAATTCCAAACAGACTCAAAATCAGAAAAAGCAGAAAGGCTCCACACCAGCTGCCACGCCACACCCCAATCAGGATGGCAAACCAGTATGGAAGAAAAAGCCTAACAAGGAAGAAACTGTTGCTCAATGTTTTGGCCCTCGCAGCGATAATAAGAATTTTGGTGATGCTGAGTTTCTCAGGCTGGGCGTTGATGACCCTCGGTTTAAAACCGCCTCTTATTACGCTCCTGGTGCTGCAGCTTCCTTGTTTGATTCCATGGTCACTGTGAGTGATGGCCCTGATGGTAAGAAGAGAGTTACCTTTCATACCACAATTGAGGTTGACCCTACTAAACCAGGTTTCGAAGTTTTCCTAGCTCAAATTGATGCATTCAAAAAGCCAGCCACCTTCCAGCAGACTCAGAACTTCTGGGAGAATCAGGCTTCTACTCAGAATAACATCTCTGAGTATTTTAGAGGTACCACACCTGGTGCCGGTGGTTCTGCAGTTGAAATTGAAACTTTTGAAATGACTGATGAAACTAATTGA

Protein

MSSNVSWADQVETVNRRQRSRSRGRSQNRTNASNPLSWFTSIIDESNGNFISLMPHSGVPTGMGTAAQQCGYWYRAPTVYQVRRGKRVPLPPVWYFYFLGTGPHANAAYGTAMDGVFWVKTKNGQIDPKSTKALGVRDSGTDPRRANIPNLPEGLRVNVPNASRPQSRAQSQTRSQNTSRASSVSRNGSRAPSVDRTKEDLKAVVSQLLAEMGISKNSKQTQNQKKQKGSTPAATPHPNQDGKPVWKKKPNKEETVAQCFGPRSDNKNFGDAEFLRLGVDDPRFKTASYYAPGAAASLFDSMVTVSDGPDGKKRVTFHTTIEVDPTKPGFEVFLAQIDAFKKPATFQQTQNFWENQASTQNNISEYFRGTTPGAGGSAVEIETFEMTDETN

Function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.

Uniprot

A0A1L7HJ39   A0A493R5G0   A0A2H4MX13   A0A2H4MWX9   A0A2H4MZ50   A0A1X9JRR1   + More
A0A493R5F8   A0A493R5F6   A0A0U1WHB5   A0A0U1WHB1   B1PHJ9   A0A482JZN4   B1PHJ2   A0A3G8EWJ3   Q0Q0A1   A0A2P1G6H8   A0A3G8EWJ5   A0A2P1G6J5   A8JP04   A0A2R3NG38   A0A2P1G6P9   A0A3G1II26   A0A2P1G739   A0A410N738   A0A5B9Y683   A0A2P1G6K4   A0A482JX97   A0A482K1U9   A0A482K014   A0A2S1WCF9   A0A2D1BNM3   A0A4Y5WWA6   A0A4Y5QL59   A0A411NPT1   A0A411NPN9   A0A411NPM6   A0A411NPM0   A0A411NPM2   A0A168SP43   A0A286R3Q3   J7IL21   A0A411NPS3   A0A411NPR9   A0A4P8GMH2   A0A411NPR3   A0A3G2LYG4   A7LKV4   A0A411NPU4   A0A075ED93   B7UCN1   A0A411NPQ8   A0A411NPV0   A0A2U8QMV0   A0A068BIG8   A0A023J7B8  

Pubmed

25463600    30704076    30285857    28549438    27125516    18420807    + More
30447246    16894183    29618817    17617433    28654418    30171801    30103259    31419711    29704627    31207129    31067830    27103490    22966198    25279722    23381394    29770590    26512689   

EMBL

KF294380    APU57648.1    MK163627    QBG64662.1    KY370050    ATP66770.1    + More
KY370045    ATP66741.1    KY370054    ATP66792.1    KX964649    AQW43028.1    MK249069    QBG64652.1    MK249068    QBG64642.1    KJ473796    AIA62210.1    KJ473795    AIA62204.1    EU420138    ACA52168.1    MG916904    QBP43296.1    EU420137    ACA52161.1    MH938450    AZF86134.1    DQ666342    ABG75577.1    MF094686    AVM80488.1    MH938449    AZF86128.1    MF094687    AVM80496.1    EF203065    ABQ57220.1    MF094702    AVM80791.1    MF094685    AVM80479.1    MF167434    ASK51721.1    MG557844    MF094681    MF094682    MF094683    MF094684    MF769416    MF769417    MF769418    MF769419    MF769420    MF769421    MF769422    MF769423    MF769424    MF769425    MF769426    MF769427    MF769428    MF769429    MF769430    MF769431    MF769432    MF769433    MF769434    MF769435    MF769436    MF769437    MF769438    MF769439    MF769440    MF769441    MF769442    MF769443    MF769444    MH615810    MG605087    MG605088    MG605089    MG605090    MG605091    MG775251    MG775253    AVM41574.1    AVM80443.1    AVM80452.1    AVM80461.1    AVM80470.1    AVM80528.1    AVM80537.1    AVM80546.1    AVM80555.1    AVM80564.1    AVM80573.1    AVM80582.1    AVM80591.1    AVM80600.1    AVM80609.1    AVM80618.1    AVM80627.1    AVM80636.1    AVM80645.1    AVM80654.1    AVM80663.1    AVM80672.1    AVM80681.1    AVM80690.1    AVM80699.1    AVM80708.1    AVM80717.1    AVM80726.1    AVM80735.1    AVM80744.1    AVM80753.1    AVM80762.1    AVM80771.1    AVM80780.1    AXP98443.1    AXY04078.1    AXY04079.1    AXY04080.1    AXY04087.1    AXY04096.1    MH539766    MH697599    QAS69032.1    QBP43304.1    MK977618    QEH62673.1    MF094688    AVM80504.1    MG916902    QBP43274.1    MG916901    QBP43263.1    MG916903    QBP43285.1    MG742313    AWJ64267.1    MF370205    ATN23893.1    MK651076    QDE12101.1    MK720944    QCX35164.1    MH744307    QBF53976.1    MH744280    QBF53949.1    MH744273    QBF53942.1    MH744274    QBF53943.1    MH744275    QBF53944.1    KU252649    ANC68211.1    MF577027    ASV51729.1    JX188454    AFQ37602.1    MH744322    QBF53991.1    MH744308    QBF53977.1    MH891587    QCO95414.1    MH744287    QBF53956.1    MG778701    AYN79040.1    EU031893    ABS72127.1    MH744344    QBF54013.1    KJ645697    AID57043.1    FJ473394    ACK77288.1    MH744300    QBF53969.1    MH744301    QBF53970.1    MH052682    MH891590    AWM11466.1    QCO95431.1    KJ642642    AIC83851.1    KF761675    KT021227    KT021228    AHG97489.1    ALM09362.1    ALM09368.1   

Proteomes

UP000204448    UP000203395    UP000157060    UP000137012    UP000100808    UP000147155    + More
UP000096660    UP000105572    UP000133882    UP000097949    UP000111801    UP000113720    UP000152961   

Pfam

PF00937   Corona_nucleoca

Interpro

IPR001218   Corona_nucleocap
IPR037179   Nucleocapsid_C
IPR037195   Nucleocapsid_N
IPR042548   ALPHA_CORONA_NCAP

SUPFAM

SSF103068   SSF103068
SSF110304   SSF110304

ProteinModelPortal

A0A1L7HJ39   A0A493R5G0   A0A2H4MX13   A0A2H4MWX9   A0A2H4MZ50   A0A1X9JRR1   + More
A0A493R5F8   A0A493R5F6   A0A0U1WHB5   A0A0U1WHB1   B1PHJ9   A0A482JZN4   B1PHJ2   A0A3G8EWJ3   Q0Q0A1   A0A2P1G6H8   A0A3G8EWJ5   A0A2P1G6J5   A8JP04   A0A2R3NG38   A0A2P1G6P9   A0A3G1II26   A0A2P1G739   A0A410N738   A0A5B9Y683   A0A2P1G6K4   A0A482JX97   A0A482K1U9   A0A482K014   A0A2S1WCF9   A0A2D1BNM3   A0A4Y5WWA6   A0A4Y5QL59   A0A411NPT1   A0A411NPN9   A0A411NPM6   A0A411NPM0   A0A411NPM2   A0A168SP43   A0A286R3Q3   J7IL21   A0A411NPS3   A0A411NPR9   A0A4P8GMH2   A0A411NPR3   A0A3G2LYG4   A7LKV4   A0A411NPU4   A0A075ED93   B7UCN1   A0A411NPQ8   A0A411NPV0   A0A2U8QMV0   A0A068BIG8   A0A023J7B8  

PDB

5EPW     E-value=1.25247e-13,     Score=186