Strain

CHINA_MURINE_2011_NC_034972 (Region: China;  Strain: Coronavirus AcCoV-JC34, complete genome.;  Date: 2011)

Gene

membrane protein

Description

Annotated in NCBI,  membrane protein

Location

NC_034972(+):24643-25389

GenBank Accession

YP_009380524.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGGTACTCTTTTGTGAGTTTAATGACACTGCCACCAATGGCTGTGAAGCCTGTGTTAATCAGGGCTGCACAGGTAATGGTGTCACTAGTGCCAGCATCACTTGGCATTTGCTGAACTGGAACTTTAGCTGGAGTGTTATACTCACTGTTTTTGTTGCAGTTCTGCAGTATGGCAATCTTAAGTACAGCATGATTCTGTACATCCTTAAAATGATCATCATGTGGTTGCTATGGCCTATTGTCATAGCACTAACCATTTTTGATGCCATTGAAACCTTCAATCAGGAGCGCTATGTCATGTTTGGATTCAGCATTGCTCTTGGTGTGGTCACGTTGATACTCTGGATTATGTACTTCGTAAACAGCTTTAGGCTTTACAGACGTACTAACTCCTGGTGGAGTTTCAACCCAGAGACCAATGCCATAATCTGTGTTTCAGTCATGGGGCGAAACATAACCATGCCAACCCCAGTCTGCCCCACAGGTGTCACACTAACGCTTCTTTCAGGAACGCTCTATGTTGAAGGGCAACGTGCTGCCACAGGCGTGAATCTTGACAATCTCCCTAGTTACGTTACTGTAGCAAAACCTGGAGTCACTATAGTTTACCACCGTGTTGGTAAATCAGTACGTGTCTCCACAGCTACGGGATGGATGTACTATGTCAAGAGTAAAGCAGGTGATTATTCTGCCTACTCCAGTGGTGGCAATCTATCAGATCAGGAACAACTGCTTCACATGGTCTAA

Protein

MVLFCEFNDTATNGCEACVNQGCTGNGVTSASITWHLLNWNFSWSVILTVFVAVLQYGNLKYSMILYILKMIIMWLLWPIVIALTIFDAIETFNQERYVMFGFSIALGVVTLILWIMYFVNSFRLYRRTNSWWSFNPETNAIICVSVMGRNITMPTPVCPTGVTLTLLSGTLYVEGQRAATGVNLDNLPSYVTVAKPGVTIVYHRVGKSVRVSTATGWMYYVKSKAGDYSAYSSGGNLSDQEQLLHMV

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.

Similarity

Belongs to the alphacoronaviruses M protein family.

Keywords

Glycoprotein   Host Golgi apparatus   Host membrane   Membrane   Transmembrane   Transmembrane helix   Viral envelope protein   Viral matrix protein   Virion   Reference proteome  

Feature

chain  Membrane protein

Uniprot

A0A1X9JJV5   A0A2H4MX25   A0A2H4MXE5   A0A1L7HJ65   A0A2H4MWY4   A0A481S0S6   + More
G8J7G9   F6M1R4   B7T076   B7T066   Q5FX57   Q6TPL0   A0A1D8ELQ6   Q64FR0   B7T4B3   A0A0U2TVR6   Q9DY23   G8A505   M4I7F1   A0A384VGP5   A0A222UC68   H9TEW2   Q6TPL1   A0A0D5ZYB2   M4I7F5   A0A0Y0R0E2   Q0PL26   Q5FX58   Q0PKZ1   A0A384V9R1   A0A384VA81   A0A384V9Q6   R9RZN0   Q88514   A7UJ02   A0A384VIC0   Q7T713   A0A384V9L3   M4I824   Q6PQ04   C0J8Y5   P33464   A0A384V9G9   A0A384V9E4   A0A3S6JCJ2   Q9WKM6   E7E031   Q0PL00   F1CNZ1   P04135   Q5G1S6   A0A514KFM3   A0A514KFK1   S6B903   Q1W2N8   A0A1S6KDW8   D2WXM2   S6CE17   A0A1L7NS55   Q5D578   Q0ZVX1   H9TEX6   Q5G1S5   G3CI08   A0A172B6J4   I3QKR3   U3Q0B8   A0A1B4X968   Q0PL09   C6K2U0   A0A514KFL5   A0A224ANT6   A0A0K2SF30   A0A0E3GM58   Q5DQ89   A0A0K2BMP6   A0A514KFJ6   A0A1L6BQB0   P24412   D3XGJ7   A0A222UBY5   Q09PH1   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   P09175   A0A514KFK2   Q6T524   Q64FQ9   Q7T6S9   Q19NU4   A0A088ND96   Q80RP1   C6GHD0   Q8JVR1   C5IJ46   E0AH02   C5IJ38  

Pubmed

28549438    30285857    25463600    30704076    22609354    22002680    + More
19036814    18306032    27619563    21481551    22542271    25953186    17023013    25890036    8546012    20229183    19162099    1662846    10365166    2841792    3035066    2825819    10805807    3008432    11152504    1309909    7636969    25180686    27840394    16704791    17275120    23043168    20603153    26221765    2174956    20079778    2845226    15177889    12505636    8839428   

EMBL

KX964649    AQW43026.1    KY370054    ATP66791.1    KY370050    ATP66769.1    + More
KF294380    APU57647.1    KY370045    ATP66740.1    MK163627    QBG64660.1    JN856008    AEQ61972.1    JF682842    AEE69327.1    EU856362    ACJ63247.1    EU856361    ACJ63236.1    AY884049    KC175340    KC175341    AAW57899.1    AFX81102.1    AFX81112.1    AY390344    AAQ96368.1    KX689261    AOT21923.1    AY704916    AAU29609.1    EU924790    EU924791    HQ450377    ACJ64180.1    ACJ64189.1    ADU17739.1    KR061459    ALR84918.1    AF302262    AAG30226.1    GU146061    ADB10854.1    JQ693056    AFZ88851.1    KX900410    ASV64433.1    KX512809    ASR18941.1    JQ404409    AFG19730.1    AY390343    AAQ96367.1    KP981644    AKA65834.1    JQ693055    AFZ88850.1    KT696544    AMB66492.1    DQ811785    ABG89300.1    AY884048    AAW57898.1    DQ811789    ABG89329.1    KX900408    KX900409    ASV64415.1    ASV64424.1    KX900397    ASV64317.1    KX900396    KX900399    KX900400    KX900401    KX900403    KX900405    KX900406    KX900407    ASV64308.1    ASV64335.1    ASV64343.1    ASV64353.1    ASV64371.1    ASV64388.1    ASV64397.1    ASV64406.1    KC962433    AGM75130.1    Z35758    CAA84810.1    EU074218    FJ755618    ABU49663.1    ACN71200.1    KX900411    ASV64442.1    AY335549    DQ201447    AAQ02626.1    ABC72418.1    KX900404    ASV64379.1    JQ693053    AFZ88848.1    AY587883    AAT00646.1    FJ009114    ACN60154.1    X55980    X60056    KX900398    ASV64326.1    KX900395    ASV64299.1    KY406735    ASV45152.1    AF104420    AAC96007.1    HQ450376    ADU17730.1    DQ811788    ABG89323.1    HQ462571    ADY39744.1    M21627    X05598    X06371    AJ271965    M14878    AY864661    AAW66660.1    MK986745    QDI78404.1    MK986743    QDI78402.1    AB781790    BAN67923.1    DQ443743    ABD97839.1    JQ693054    KU729220    KX499468    KX900393    KX900394    KX900402    MK166015    AFZ88849.1    AML22781.1    AQT01353.1    ASV64281.1    ASV64290.1    ASV64362.1    QCZ41128.1    GQ477367    ADB28912.1    AB781788    BAN67905.1    LC190907    BAW32707.1    AY899209    AAX18705.1    DQ112226    AAZ91441.1    JQ404410    KY063616    KY063617    KY063618    AFG19744.1    ASB15743.1    ASB15753.1    ASB15761.1    AY864662    AAW66661.1    HM776941    AEM55570.1    KM347965    AKG92643.1    JQ700303    AFK10485.1    KF273109    AGW80452.1    LC119077    BAV31352.1    DQ811787    ABG89312.1    GQ152141    ACS44222.1    MK986744    QDI78403.1    LC215871    BBA21171.1    LC029419    BAS25713.1    KP202848    AKA60058.1    AY548235    AAT45197.1    KP849472    AKZ66477.1    MK986737    QDI78396.1    KX083668    APQ31246.1    Z24675    GU338457    ADD49361.1    KX512810    ASR18949.1    DQ848678    ABI14450.1    MK986742    QDI78401.1    MK986746    QDI78405.1    MK986739    QDI78398.1    MK986741    QDI78400.1    Y00560    MK986740    QDI78399.1    AY436635    AAR11075.1    AY704917    AAU29610.1    AY342160    DQ517438    ABF72147.1    KJ879395    AIN55916.1    AF502583    AAO33711.1    FJ938055    ACT10900.1    AB086903    BAC01158.1    FJ943762    ACR46122.1    HQ012372    ADL71502.1    FJ943761    ACR46114.1   

Proteomes

UP000203395    UP000204448    UP000153699    UP000155481    UP000165378    UP000125818    + More
UP000119169    UP000115330    UP000166023    UP000145148    UP000158285    UP000123026    UP000111647    UP000121388    UP000156732    UP000137024    UP000113525    UP000001440    UP000158504    UP000131894    UP000129066    UP000106470    UP000166047    UP000150460    UP000272061    UP000149523    UP000164750    UP000098772    UP000174600    UP000118215    UP000162682    UP000110620   

PRIDE

P33464    P04135    P24412    P09175    Q7T6S9   

Pfam

PF01635   Corona_M

Interpro

IPR002574   Corona_M
IPR042551   ALPHA_CORONA_M

ProteinModelPortal

A0A1X9JJV5   A0A2H4MX25   A0A2H4MXE5   A0A1L7HJ65   A0A2H4MWY4   A0A481S0S6   + More
G8J7G9   F6M1R4   B7T076   B7T066   Q5FX57   Q6TPL0   A0A1D8ELQ6   Q64FR0   B7T4B3   A0A0U2TVR6   Q9DY23   G8A505   M4I7F1   A0A384VGP5   A0A222UC68   H9TEW2   Q6TPL1   A0A0D5ZYB2   M4I7F5   A0A0Y0R0E2   Q0PL26   Q5FX58   Q0PKZ1   A0A384V9R1   A0A384VA81   A0A384V9Q6   R9RZN0   Q88514   A7UJ02   A0A384VIC0   Q7T713   A0A384V9L3   M4I824   Q6PQ04   C0J8Y5   P33464   A0A384V9G9   A0A384V9E4   A0A3S6JCJ2   Q9WKM6   E7E031   Q0PL00   F1CNZ1   P04135   Q5G1S6   A0A514KFM3   A0A514KFK1   S6B903   Q1W2N8   A0A1S6KDW8   D2WXM2   S6CE17   A0A1L7NS55   Q5D578   Q0ZVX1   H9TEX6   Q5G1S5   G3CI08   A0A172B6J4   I3QKR3   U3Q0B8   A0A1B4X968   Q0PL09   C6K2U0   A0A514KFL5   A0A224ANT6   A0A0K2SF30   A0A0E3GM58   Q5DQ89   A0A0K2BMP6   A0A514KFJ6   A0A1L6BQB0   P24412   D3XGJ7   A0A222UBY5   Q09PH1   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   P09175   A0A514KFK2   Q6T524   Q64FQ9   Q7T6S9   Q19NU4   A0A088ND96   Q80RP1   C6GHD0   Q8JVR1   C5IJ46   E0AH02   C5IJ38  

PDB

3Q2V     E-value=1.02704,     Score=72