Strain

CHINA_MURINE_2015_NC_035191 (Region: China;  Strain: Wencheng Sm shrew coronavirus isolate Xingguo-101 ORF1ab polyprotein, spike glycoprotein, envelope protein, membrane protein, and nucleocapsid protein genes, complete cds.;  Date: 2015)

Gene

membrane protein

Description

Annotated in NCBI,  membrane protein

Location

NC_035191(+):23546-24235

GenBank Accession

YP_009389427.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGTCTAATAGTAGTGGAAATATAACATTATCTGTGAGTGAACTCACGCAACATTTGACCAATTGGTCATTTAGTTGGAATATAATTCTAACTGTAATGATCATTGTGTTGCAGTATGGTTTTATTAAATATGGAAGGGTTGTTTATGCATTGAAAATGTTTGTGCTGTGGCTTTTATGGCCATTGGTTTTGGCATTGAGTATATTCAATGCTATTGTAAGCTTGAATTATAGCTATGTAATGTTTGCCTTCTGTATTGTATTGATTTGTGTGACATTTGGGTTGTGGTTGGCATACTTTGTAAACAGCATTAAATTGTACAGAAGAACGCATAGTCCTTGGTCTTTTGATCCATCCACTAATGCGGTCCTGTGCTTTTCTGTGCTTGGAAGAAGTCATGCCATTCCAGTGCCAACCGTGCCAACCGGAATCACTTTAACTCTGTTGTCTGGACAATTGAATGTTGAAGGAATTCCAATTTGTAATGGTTTGAATTTTCATGATATGCCTGAGTTCATTAGTGTTGCCAAACCTAATGTTACAATTCTTTATGAAGTGAGATCAAGAAAAGGCAATACGAATACAAAAACTGGTTGGGTTTATTATGTTAGGAGTAAACATGGAGATTATTCCGCATATAGATCTCAACCAACATTGAATAATGACGATTTAATTCTACATTTAGCCTAA

Protein

MSNSSGNITLSVSELTQHLTNWSFSWNIILTVMIIVLQYGFIKYGRVVYALKMFVLWLLWPLVLALSIFNAIVSLNYSYVMFAFCIVLICVTFGLWLAYFVNSIKLYRRTHSPWSFDPSTNAVLCFSVLGRSHAIPVPTVPTGITLTLLSGQLNVEGIPICNGLNFHDMPEFISVAKPNVTILYEVRSRKGNTNTKTGWVYYVRSKHGDYSAYRSQPTLNNDDLILHLA

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.

Miscellaneous

Bat coronavirus 512/2005 is highly similar to porcine epidemic diarrhea virus (PEDV).

Similarity

Belongs to the alphacoronaviruses M protein family.

Keywords

Glycoprotein   Host Golgi apparatus   Host membrane   Membrane   Transmembrane   Transmembrane helix   Viral envelope protein   Viral matrix protein   Virion   Reference proteome  

Feature

chain  Membrane protein

Uniprot

A0A240FW19   A0A240FW14   A0A240FW33   A0A240FW42   A0A240FW28   A0A240FW52   + More
A0A240FW56   F1DB17   A0A0U1WHB0   A0A0U1WJT9   F1DB10   B1PHJ1   A0A482K0E0   B1PHJ8   A0A4Y6GME6   A0A3G8EYW6   A0A3G8EWJ7   A0A482K022   A0A482JXA6   A0A482K1V6   A0A0U1UYW3   A0A0U1UZB2   A0A0U1WJV1   A0A0U1WHF2   A0A2P1G6J7   A8JP03   A0A2P1G6H6   F1DB23   K4KCT7   A0A3G1II33   A0A346LQ18   K4K1Y9   A0A4Y5QL73   A0A0U1WJU7   K4JZP2   A0A1X9JJV5   A0A410N739   A0A2D1BHB6   A0A2P1G6R8   K4JZB1   A0A4Y5QL69   A0A0U1WHF0   F1DAX9   A0A249JPV0   A0A2P1G6K5   A0A0U1YIU9   A0A5B9Y8P9   A0A1P8NPR6   A8JNZ5   A0A0U1YFS8   A0A2K8IYQ4   A0A2H4MXE5   A0A2S1WCF2   A0A0F7L0A6   A0A286L9K5   G8G0X2   P59771   A0A2H4MWY4   A0A2H4MX25   A0A2P1G6J1   I6YQD5   A0A286L9N6   A0A1L7HJ65   A0A5K1KB33   A0A1Y0DD49   A0A481S0S6   A0A3G8EWC3   B1PHK5   A0A482K1Y2   A0A3G3NHN0   A0A3G3NGU8   Q0Q463   A0A4Y6GN26   A0A3G3NH93   A0A4Y6GMD9   A0A2U8QMV7   A0A4Y6GMD0   A0A3G3NGI6   A0A3G3NGS9   A0A166ZM26   L0H811   W8GTY3   A0A0U1UZC6   A0A4Y6GN38   A0A4D6FTR9   W8GLL9   A0A2R4H2G5   G8G0X6   J9ZZ62   G8G0W9   W8GL50   A0A2U8QMV8   A0A4P8GK29   Q52QS3   D3U0E7   A0A4Y5MW43   A0A0B4ZZ41   A0A5K1KBA1   G8G0Y1   A0A075EBH8  

Pubmed

28637760    19239771    22561208    27125516    18420807    30447246    + More
29618817    17617433    22933277    28654418    31067830    28549438    30171801    31207129    31419711    28284624    29540176    30285857    29704627    26112783    28854955    22528639    8291230    9782358    11724265    8397280    23599287    26611909    25463600    28534849    30704076    30103259    16840328    29770590    26847648    23469356    25279722    21210162   

EMBL

KY967717    ASF90452.1    KY967715    ASF90446.1    KY967724    ASF90467.1    + More
KY967725    KY967726    ASF90472.1    ASF90477.1    KY967723    ASF90462.1    KY967733    KY967735    ASF90488.1    ASF90498.1    KY967734    ASF90493.1    HQ728485    ADX59491.1    KJ473795    AIA62203.1    KJ473796    AIA62209.1    HQ728484    ADX59485.1    EU420137    ACA52160.1    MG916901    QBP43262.1    EU420138    ACA52167.1    MK211373    QDF43812.1    MH938450    AZF86133.1    MH938449    AZF86127.1    MG916904    QBP43295.1    MG916903    QBP43284.1    MG916902    QBP43273.1    KJ473800    AIA62237.1    KJ473797    AIA62215.1    KJ473799    AIA62230.1    KJ473809    AIA62268.1    MF094688    AVM80503.1    EF203065    EF203066    EF203067    ABQ57219.1    ABQ57227.1    ABQ57235.1    MF094685    AVM80478.1    HQ728486    ADX59498.1    JQ989272    JQ989273    AFU92125.1    AFU92134.1    MF167434    ASK51720.1    MH615810    AXP98442.1    JQ989270    AFU92107.1    MK720945    MK720946    QCX35173.1    QCX35184.1    KJ473798    AIA62223.1    JQ989266    JQ989267    JQ989268    JQ989269    AFU92073.1    AFU92081.1    AFU92089.1    AFU92098.1    KX964649    AQW43026.1    MH539766    QAS69031.1    MF370205    ATN23892.1    MG557844    MF094681    MF094682    MF094683    MF094684    MF769416    MF769417    MF769418    MF769419    MF769420    MF769421    MF769422    MF769423    MF769424    MF769425    MF769426    MF769427    MF769428    MF769429    MF769430    MF769431    MF769432    MF769433    MF769434    MF769435    MF769436    MF769437    MF769438    MF769439    MF769440    MF769441    MF769442    MF769443    MF769444    MG605090    MG605091    MK651076    AVM41573.1    AVM80442.1    AVM80451.1    AVM80460.1    AVM80469.1    AVM80527.1    AVM80536.1    AVM80545.1    AVM80554.1    AVM80563.1    AVM80572.1    AVM80581.1    AVM80590.1    AVM80599.1    AVM80608.1    AVM80617.1    AVM80626.1    AVM80635.1    AVM80644.1    AVM80653.1    AVM80662.1    AVM80671.1    AVM80680.1    AVM80689.1    AVM80698.1    AVM80707.1    AVM80716.1    AVM80725.1    AVM80734.1    AVM80743.1    AVM80752.1    AVM80761.1    AVM80770.1    AVM80779.1    AXY04086.1    AXY04095.1    QDE12100.1    JQ989271    AFU92116.1    MK720944    QCX35163.1    KJ473808    AIA62262.1    HQ728480    ADX59454.1    MF462814    ASY04646.1    MF094687    AVM80495.1    KJ857390    AJD09513.1    MK977618    QEH62672.1    KU893873    APX42140.1    EF203064    ABQ57211.1    KJ857395    AJD09518.1    KY619828    ATJ03683.1    KY370050    ATP66769.1    MG742313    AWJ64266.1    KR610991    KR610992    AKH45335.1    KY486713    KX839247    AST13132.1    AST13224.1    JN089727    JN089733    AER39408.1    AER39414.1    Z24733    AF353511    Z14976    KY370045    ATP66740.1    KY370054    ATP66791.1    MF094686    AVM80487.1    JX002685    JX002693    KC109141    KC210146    KP162057    KT323979    AFN66538.1    AFN66546.1    AGD98688.1    AGG55743.1    AJW67221.1    ALS35471.1    KX839250    AST13242.1    KF294380    APU57647.1    MH726382    QCQ19921.1    KY929405    ART85702.1    MK163627    QBG64660.1    MH938448    AZF86121.1    EU420139    ACA52174.1    MH697599    QBP43303.1    MH687943    MH687945    MH687946    MH687948    MH687954    MH687956    MH687958    AYR18458.1    AYR18470.1    AYR18476.1    AYR18484.1    AYR18516.1    AYR18528.1    AYR18540.1    MH687941    AYR18445.1    DQ648858    MK211370    QDF43797.1    MH687963    MH687964    AYR18570.1    AYR18576.1    MK211371    QDF43802.1    MH052684    AWM11477.1    MK211369    QDF43792.1    MH687938    AYR18427.1    MH687937    MH687955    MH687960    MH687961    MH687965    AYR18421.1    AYR18522.1    AYR18552.1    AYR18558.1    AYR18582.1    KU182966    ANA96051.1    KC196276    AGA94623.1    KJ001727    AHK25065.1    KJ473807    AIA62255.1    MK211372    QDF43807.1    MK606369    QCB65309.1    KJ001733    KJ001734    KJ645644    KR265824    KR265845    AHK25071.1    AHK25072.1    AID56724.1    AKJ22094.1    AKJ22208.1    MH004416    MH004421    MH243319    AVU05371.1    AVU05406.1    QBA57561.1    JN089737    JN173338    AER39418.1    AET71237.1    JX512906    AFS63728.1    JN089730    KJ001737    AER39411.1    AHK25075.1    KJ001735    AHK25073.1    MH052681    MH052682    MH052685    MH891584    MH891585    MH891586    MH891587    MH891588    MH891590    AWM11459.1    AWM11465.1    AWM11483.1    QCO95395.1    QCO95401.1    QCO95407.1    QCO95413.1    QCO95419.1    QCO95430.1    MH891589    QCO95425.1    AY974335    AAX84831.1    FJ687457    ACV81757.1    MK796238    QCW07224.1    KM604664    AJD80651.1    MH726406    QCQ20065.1    JN089742    MH726405    MK644604    AER39423.1    QCQ20059.1    QFG01709.1    KJ645674    AID56904.1   

Proteomes

UP000202100    UP000137012    UP000157060    UP000147155    UP000100808    UP000126502    + More
UP000106776    UP000135768    UP000103794    UP000096660    UP000130662    UP000152921    UP000112496    UP000126962    UP000155419    UP000110898    UP000119818    UP000123997    UP000126615    UP000132096    UP000203395    UP000162430    UP000104963    UP000166619    UP000156820    UP000171486    UP000008159    UP000096075    UP000134644    UP000180353    UP000180354    UP000204448    UP000143524    UP000113079    UP000170972    UP000106394    UP000109831    UP000130673    UP000168169    UP000112678   

Pfam

PF01635   Corona_M

Interpro

IPR002574   Corona_M
IPR042551   ALPHA_CORONA_M

ProteinModelPortal

A0A240FW19   A0A240FW14   A0A240FW33   A0A240FW42   A0A240FW28   A0A240FW52   + More
A0A240FW56   F1DB17   A0A0U1WHB0   A0A0U1WJT9   F1DB10   B1PHJ1   A0A482K0E0   B1PHJ8   A0A4Y6GME6   A0A3G8EYW6   A0A3G8EWJ7   A0A482K022   A0A482JXA6   A0A482K1V6   A0A0U1UYW3   A0A0U1UZB2   A0A0U1WJV1   A0A0U1WHF2   A0A2P1G6J7   A8JP03   A0A2P1G6H6   F1DB23   K4KCT7   A0A3G1II33   A0A346LQ18   K4K1Y9   A0A4Y5QL73   A0A0U1WJU7   K4JZP2   A0A1X9JJV5   A0A410N739   A0A2D1BHB6   A0A2P1G6R8   K4JZB1   A0A4Y5QL69   A0A0U1WHF0   F1DAX9   A0A249JPV0   A0A2P1G6K5   A0A0U1YIU9   A0A5B9Y8P9   A0A1P8NPR6   A8JNZ5   A0A0U1YFS8   A0A2K8IYQ4   A0A2H4MXE5   A0A2S1WCF2   A0A0F7L0A6   A0A286L9K5   G8G0X2   P59771   A0A2H4MWY4   A0A2H4MX25   A0A2P1G6J1   I6YQD5   A0A286L9N6   A0A1L7HJ65   A0A5K1KB33   A0A1Y0DD49   A0A481S0S6   A0A3G8EWC3   B1PHK5   A0A482K1Y2   A0A3G3NHN0   A0A3G3NGU8   Q0Q463   A0A4Y6GN26   A0A3G3NH93   A0A4Y6GMD9   A0A2U8QMV7   A0A4Y6GMD0   A0A3G3NGI6   A0A3G3NGS9   A0A166ZM26   L0H811   W8GTY3   A0A0U1UZC6   A0A4Y6GN38   A0A4D6FTR9   W8GLL9   A0A2R4H2G5   G8G0X6   J9ZZ62   G8G0W9   W8GL50   A0A2U8QMV8   A0A4P8GK29   Q52QS3   D3U0E7   A0A4Y5MW43   A0A0B4ZZ41   A0A5K1KBA1   G8G0Y1   A0A075EBH8  

PDB

2IUK     E-value=6.41525,     Score=65