Strain

CANADA_AVIAN_2007_NC_010800 (Region: Canada;  Strain: Turkey coronavirus, complete genome.;  Date: 2007)

Gene

nucleocapsid protein

Description

Annotated in NCBI,  nucleocapsid protein

Location

NC_010800(+):26054-27283

GenBank Accession

YP_001941174.1

Full name

Nucleoprotein      

Alternative Name

Nucleocapsid protein

CDS

ATGGCAAGCGGTAAGGCAACTGGCAAGACAGATGCCCCAGCGCCGGTCATCAAACTAGGAGGACCAAAGCCACCTAAAGTTGGTTCTTCTGGAAATGCATCTTGGTTTCAATCAATAAAAGCCAAGAAGCTAAATACACCTCAACCTAAGTTTGAAGGTAGCGGTGTTCCTGATAATGAAAATATTAAAACAAGCCAGCAGCATGGATACTGGAGACGCCAAGCCAGGTTTAAGCCAGGTAAAGGCGGAAGAAAACCAGTCCCAGATGCTTGGTACTTCTATTATACTGGAACAGGACCAGCCGCTGACCTGAATTGGGGTGATACCCAAGATGGTATAGTGTGGGTTGCTGCAAAGGGTGCTGATGTTAAATCTAGATCTAACCAGGGTACAAGGGACCCTGACAAGTTTGACCAATATCCACTACGATTCTCGGACGGAGGACCTGATAGTAATTTCCGTTGGGACTTTATTCCTCTGCATCGTGGTAGGAGTGGAAGATCAACAGCAGCTTCATCAGCAGCATCTAGTAGAGCACCGTCGCGTGACGGCTCGCGTGGTCGTAGAAGTGGTTCTGAAGATGATCTTATTGCTCGTGCAGCAAAGATAATCCAGGATCAGCAGAAGAAGGGTTCTCGCATTACTAAGGCTAAGGCTGATGAAATGGCTCACCGCCGGTATTGCAAGCGCACTGTTCCACCTGGTTATAAGGTTGATCAAGTATTTGGTCCCCGTACTAAAGGTAGGGAGGGAAATTTTGGTGATGACAAAATGAATGAGGAAGGTATTAAGGATGGGCGTGTTACGGCAATGCTCAACCTAGTCCCTAGCAGCCATGCTTGTCTTTTTGGAAGCAAAGTGACGCCCAAACTTCAACCAGATGGGCTTCACTTGCGATTTGAATTTACTACTGTGGTCCCGCGTGATGATCCGCAGTTTGCTAATTATGTGCAAATTTGTGATCAGTGTGTCGATGGTATAGGAACACGTCCAAAAGACAATGAACCCAGACCAAAGTCACGCCCAAGTTCTAGACCTGCTACAAGAGGAAATTCTCCAGCGCCAAGACAACAGCGCCCAAAGAAGGAGAAAAAGCCAAAGAAGCAGGATGATGAAGTAGATAAAGCGTTGACCTCGGATGAGGAGAGGAACAATGCACAGCTGGAATTTGATGATGAACCCAAGGTAATTAATTGGGGGGATTCAGCCCTAGGAGAGAATGAGTTGTAG

Protein

MASGKATGKTDAPAPVIKLGGPKPPKVGSSGNASWFQSIKAKKLNTPQPKFEGSGVPDNENIKTSQQHGYWRRQARFKPGKGGRKPVPDAWYFYYTGTGPAADLNWGDTQDGIVWVAAKGADVKSRSNQGTRDPDKFDQYPLRFSDGGPDSNFRWDFIPLHRGRSGRSTAASSAASSRAPSRDGSRGRRSGSEDDLIARAAKIIQDQQKKGSRITKAKADEMAHRRYCKRTVPPGYKVDQVFGPRTKGREGNFGDDKMNEEGIKDGRVTAMLNLVPSSHACLFGSKVTPKLQPDGLHLRFEFTTVVPRDDPQFANYVQICDQCVDGIGTRPKDNEPRPKSRPSSRPATRGNSPAPRQQRPKKEKKPKKQDDEVDKALTSDEERNNAQLEFDDEPKVINWGDSALGENEL

Function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.

Similarity

Belongs to the gammacoronavirus nucleocapsid protein family.

Keywords

ADP-ribosylation   Disulfide bond   Host Golgi apparatus   Phosphoprotein   Ribonucleoprotein   RNA-binding   Transcription   Transcription regulation   Viral nucleoprotein   Virion   3D-structure  

Feature

chain  Nucleoprotein

Uniprot

B3FHV3   Q9PZ49   A0A172Q3S6   A0A172Q3Q4   Q8JMI6   A0A172Q3U2   + More
A0MNZ2   A5YVH1   Q6UQG9   J7I3U1   A0A4Y5QCU0   A0A0N9Q6T2   G3C7A3   P32923   A5YVH0   A0A172Q3Q7   A0A0D4CFP1   Q6UQG8   Q80AG5   A0A1X9Y2S3   I6YVZ4   A0A1X9Y2N3   C9DSU5   F4MIQ3   Q5MBP6   I6YVZ0   I6Y078   B2MWM6   I6YAW4   A0A286LPM4   Q4G2X4   D3Y283   A0A0U1WK30   Q4G2X6   Q6UQG7   E5D0A8   C9DST4   A0A0C5GWH7   A0A5J6RDW7   Q5XL97   A0A286LPL6   Q80AG6   G3C777   F6KSZ3   B3VN14   A0A3G6IQA9   A0A0D4CFA5   F4MIR3   B8QAZ5   B9VQ24   M4I7F3   Q58J40   A0A1X9Y2Z0   J7I3T6   G3C7G6   A0A1X9Y2P3   F4MIU3   A0A1P8SFN3   A0A023PNX0   A0A172Q3U7   A0A0C5H8G8   A0A0E3TJA7   B5LSV9   Q2PZJ3   Q4G2X1   M4I7E7   I6Z446   A0A172Q3W7   A0A1X9Y2T3   F6KSZ2   U5YEL3   Q4G2X7   Q2I1B3   Q58J37   A0A1X9Y2Q5   E5D086   C9DSV6   J7KFX0   A0A140HEX2   Q4G2X3   A0A516UWE3   I6Z8C2   A0A346T2W1   Q58J41   B3TD70   Q2PZI9   A0A1L1XIT8   A0A0C5GMF6   A5Z0W5   M4I9Y4   A0A0E3SVG4   Q4G2X8   Q6R4N8   A0A172Q3U6   A0A1U9WSQ2   U5S076   A0A172Q3X7   A0A3G6IUI8   G9I0W9   G3G1B1  

Pubmed

18468711    10581391    10393500    19242786    15187369    23202499    + More
31439703    26262637    21994806    1966426    1332275    16775348    28116527    23065112    20022075    21539870    24613433    26482289    18295413    19102764    19219402    16025240    21909766    31561498    16990149    19781572    23203570    16927130    28495648    27793730    25843648    19835950    18514348    25843651    25667323    15183070   

EMBL

EU095850    ABW81435.1    AF111997    AF072912    KU253619    AND76849.1    + More
KU253617    KU253620    AND76833.1    AND76857.1    AY121092    AY167730    KU253616    AND76825.1    EF025537    ABK30933.1    EF591036    ABQ96870.1    AY363966    AAR15908.1    JQ977698    AFQ31017.1    MK878536    QCX19628.1    KR231009    ALH21120.1    GU393333    ADV71751.1    S55229    S48137    M85245    EF591035    ABQ96869.1    KU253618    AND76841.1    KP118885    AJT47894.1    AY363967    AAR15909.1    AY278110    AAP32083.1    KU900743    ARS22457.1    JQ964084    AFN61252.1    KU900739    ARS22417.1    GQ427174    ACV87246.1    FJ904713    FJ904716    FJ904718    FJ904719    KC506155    KF696629    KJ425485    KF996283    KR265092    ADA83474.1    ADA83504.1    ADA83524.1    ADA83534.1    AGJ98444.1    AHB79530.1    AHX25900.1    AIB54176.1    ART35356.1    AY839145    EF602442    EU418976    AAV88464.1    ABQ84789.1    ACB59379.1    JQ964079    AFN61247.1    JQ964077    AFN61245.1    EU637854    ACC94333.1    JQ964080    AFN61248.1    MF462335    ASU92403.1    AY790348    AAX19436.1    GU386375    ADC79658.1    KF996286    KJ669722    AIB54179.1    AJP08748.1    AY790346    AAX19434.1    AY363968    AAR15910.1    GQ504723    ADP06485.1    GQ427173    ACV87237.1    KP036504    AJP16737.1    MK887118    QEY95723.1    AY761141    AAV28729.1    MF462334    ASU92395.1    AY277721    AAP32046.1    GU393331    ADV71725.1    HQ607366    AEF98429.1    EU780081    KF377577    KP118880    KP118881    KP118884    KP118887    KP118888    KP118891    KP118892    KP118893    MK032179    MK032180    MK887115    ACE88710.1    AGY56147.1    AJT47849.1    AJT47858.1    AJT47885.1    AJT47912.1    AJT47921.1    AJT47948.1    AJT47957.1    AJT47966.1    AZA07849.1    AZA07858.1    QEY95720.1    MK032178    AZA07840.1    KP118882    AJT47867.1    FJ904714    ADA83482.1    EU418975    GQ504720    KY776700    KY776701    ACB59369.1    ADP06452.1    AVI69451.1    AVI69460.1    FJ589732    ACM07734.1    JQ693045    AFZ88840.1    AY942746    AAX39765.1    KY805846    ARS23161.1    JQ977697    AFQ31007.1    GU393338    ADV71813.1    KU900740    ARS22427.1    FJ904717    ADA83514.1    KX272465    APY20703.1    KJ425497    AHX26008.1    KU253622    AND76873.1    KP036503    AJP16728.1    KP662631    AKC34140.1    EU889030    ACG70920.1    DQ287910    EF213582    EF602445    EF602446    ABC02824.1    ABN04183.1    ABQ84813.1    ABQ84821.1    AY790351    AAX19439.1    JQ693046    AFZ88841.1    JQ964083    AFN61251.1    KU253624    AND76889.1    KU900744    ARS22467.1    HQ607365    AEF98428.1    KF411040    AGZ89679.1    AY790345    AAX19433.1    DQ352147    EF602456    ABC75293.1    ABQ84900.1    AY942749    AAX39768.1    KU900741    ARS22437.1    GQ504721    ADP06466.2    GQ427175    ACV87257.1    JX195177    AFQ94238.1    KT886454    AMO03299.1    AY790349    AAX19437.1    MK581202    QDQ69130.1    JQ964081    AFN61249.1    MG233398    AXT92422.1    AY942745    AAX39764.1    EU022526    ABW75147.1    DQ287914    EF602451    KX252791    ABC02828.1    ABQ84860.1    APY26734.1    KJ940501    KR265091    AJP08753.1    ART35348.1    KP036502    AJP16719.1    EF602440    ABQ84773.1    JQ693047    AFZ88842.1    KM658210    KM658212    KM658213    AKB91482.1    AKB91484.1    AKB91485.1    AY790344    AAX19432.1    AY514485    AAS00087.1    KU253623    AND76881.1    KX434790    AQY55891.1    KF360987    AGY78355.1    KU253621    AND76865.1    MK032177    AZA07831.1    JN542568    AEW43638.1    JF775530    AEO79901.1   

Proteomes

UP000106026    UP000150527    UP000097758    UP000146844    UP000105510    UP000098674    + More
UP000119721    UP000121579    UP000124016    UP000130162    UP000145806    UP000155805    UP000167075    UP000102335    UP000130254    UP000132955    UP000123786    UP000124537    UP000138275    UP000100522    UP000109170    UP000117109    UP000121165    UP000136129    UP000142905    UP000147307    UP000149934    UP000170218    UP000111271    UP000133571    UP000139706    UP000151624    UP000096390    UP000129978    UP000137477    UP000170844    UP000146859    UP000130326    UP000104663    UP000107038    UP000112634    UP000161583    UP000133437    UP000099410    UP000105210    UP000160278   

PRIDE

Q8JMI6    P32923   

Pfam

PF00937   Corona_nucleoca

Interpro

IPR037195   Nucleocapsid_N
IPR001218   Corona_nucleocap
IPR037179   Nucleocapsid_C
IPR042547   GAMMA_CORONA_NCAP

SUPFAM

SSF110304   SSF110304
SSF103068   SSF103068

ProteinModelPortal

B3FHV3   Q9PZ49   A0A172Q3S6   A0A172Q3Q4   Q8JMI6   A0A172Q3U2   + More
A0MNZ2   A5YVH1   Q6UQG9   J7I3U1   A0A4Y5QCU0   A0A0N9Q6T2   G3C7A3   P32923   A5YVH0   A0A172Q3Q7   A0A0D4CFP1   Q6UQG8   Q80AG5   A0A1X9Y2S3   I6YVZ4   A0A1X9Y2N3   C9DSU5   F4MIQ3   Q5MBP6   I6YVZ0   I6Y078   B2MWM6   I6YAW4   A0A286LPM4   Q4G2X4   D3Y283   A0A0U1WK30   Q4G2X6   Q6UQG7   E5D0A8   C9DST4   A0A0C5GWH7   A0A5J6RDW7   Q5XL97   A0A286LPL6   Q80AG6   G3C777   F6KSZ3   B3VN14   A0A3G6IQA9   A0A0D4CFA5   F4MIR3   B8QAZ5   B9VQ24   M4I7F3   Q58J40   A0A1X9Y2Z0   J7I3T6   G3C7G6   A0A1X9Y2P3   F4MIU3   A0A1P8SFN3   A0A023PNX0   A0A172Q3U7   A0A0C5H8G8   A0A0E3TJA7   B5LSV9   Q2PZJ3   Q4G2X1   M4I7E7   I6Z446   A0A172Q3W7   A0A1X9Y2T3   F6KSZ2   U5YEL3   Q4G2X7   Q2I1B3   Q58J37   A0A1X9Y2Q5   E5D086   C9DSV6   J7KFX0   A0A140HEX2   Q4G2X3   A0A516UWE3   I6Z8C2   A0A346T2W1   Q58J41   B3TD70   Q2PZI9   A0A1L1XIT8   A0A0C5GMF6   A5Z0W5   M4I9Y4   A0A0E3SVG4   Q4G2X8   Q6R4N8   A0A172Q3U6   A0A1U9WSQ2   U5S076   A0A172Q3X7   A0A3G6IUI8   G9I0W9   G3G1B1  

PDB

2C86     E-value=9.47774e-68,     Score=653