Strain

ITALY_PIG_2009_NC_028806 (Region: Italy;  Strain: Swine enteric coronavirus strain Italy/213306/2009, complete genome.;  Date: 2009)

Gene

membrane protein

Description

Annotated in NCBI,  membrane protein

Location

NC_028806(+):25646-26434

GenBank Accession

YP_009199246.1

Full name

Membrane protein      

Alternative Name

E1 glycoprotein
Matrix glycoprotein
Membrane glycoprotein

CDS

ATGAAGATTTTGTTGATATTAGCGTGTGCGATTGTATGCACATATGGCGAACGCTATTGTGCTATGAAGGACGATAAAGGTCTCTCATGTCGCAATAGCACAGCGTCTGATTGTGATGCGTGCTTCAACAAAGGCGATCTTATTTGGCATCTCGCAAACTGGAACTTCAGCTGGTCTATAATATTGATCATTTTTATTACTGTGCTACAATATGGAAGACCTCAATTCAGCTGGTTCGTGTATGGCATTAAAATGTTTATAATGTGGCTATTATGGCCCCTTGTTTTGGCTCTTACGATTTTTAATGCATACTCGGAATACCAAGTGTCCAGGTATGTAATGTTCGGCTTTAGTATTGCAGGTGCAATTGTTACAGTTGTACTTTGGATTATGTATTTCGTAAGATCCATTCAGTTGTACAGAAGGACTAAGTCTTGGTGGTCCTTTAACCCTGAGACTAACGCAATTCTTTGCGTTAGTGCACTAGGAAGAAGCTATGTGCTTCCTCTCGAAGGTGTGCCAACTGGTGTCACTTTAACTTTGCTTTCAGGGAATTTGTACGCTGAAGGGTTCAAAATTGCAGGTGGTATGAACATCGACAATTTGCCAAAATACGTAATGGTTGCATCACCCAGCAGGACTATTGTCTACACACTTGTTGGCAAAAAGTTGAAAGCAAGTAGTGCGACTGGATGGGCTTACTATGTAAAATCTAAAGCTGGTGATTACTCAACAGAGGCAAGAACTGATAATTTGAGTGAGCAAGAGAAATTATTACATATGGTATAA

Protein

MKILLILACAIVCTYGERYCAMKDDKGLSCRNSTASDCDACFNKGDLIWHLANWNFSWSIILIIFITVLQYGRPQFSWFVYGIKMFIMWLLWPLVLALTIFNAYSEYQVSRYVMFGFSIAGAIVTVVLWIMYFVRSIQLYRRTKSWWSFNPETNAILCVSALGRSYVLPLEGVPTGVTLTLLSGNLYAEGFKIAGGMNIDNLPKYVMVASPSRTIVYTLVGKKLKASSATGWAYYVKSKAGDYSTEARTDNLSEQEKLLHMV

Function

Component of the viral envelope that plays a central role in virus morphogenesis and assembly via its interactions with other viral proteins.

Subunit

Homomultimer. Interacts with envelope E protein in the budding compartment of the host cell, which is located between endoplasmic reticulum and the Golgi complex. Forms a complex with HE and S proteins. Interacts with nucleocapsid N protein. This interaction probably participates in RNA packaging into the virus.

Similarity

Belongs to the alphacoronaviruses M protein family.

Keywords

Glycoprotein   Host Golgi apparatus   Host membrane   Membrane   Transmembrane   Transmembrane helix   Viral envelope protein   Viral matrix protein   Virion   Reference proteome  

Feature

chain  Membrane protein

Uniprot

A0A0U2TVR6   A0A1D8ELQ6   P33464   A0A0Y0R0E2   Q0PL26   Q6PQ04   + More
P24412   Q9DY23   A7UJ02   Q7T713   M4I7F1   Q0PKZ1   A0A384VA81   Q0PL00   F1CNZ1   P04135   Q88514   A0A384V9Q6   A0A384V9L3   R9RZN0   M4I824   M4I7F5   G3CI08   A0A384V9E4   A0A384V9R1   A0A0E3GM58   P09175   Q1W2N8   A0A1S6KDW8   A0A384V9G9   I3QKR3   U3Q0B8   Q5FX57   A0A384VIC0   H9TEW2   Q0PL09   A0A384VGP5   Q64FR0   Q5FX58   B7T4B3   S6B903   F6M1R4   Q19NU4   A0A3S6JCJ2   Q5G1S5   A0A0D5ZYB2   Q6TPL0   A0A1L6BQB0   C0J8Y5   G8A505   B7T076   Q5G1S6   Q0ZVX1   Q6TPL1   Q5D578   H9TEX6   G8J7G9   A0A1L7NS55   Q0PL17   Q80RP1   Q9WKM6   A0A0K1RM39   B7T066   Q6T524   Q64FQ9   E7E031   D2WXM2   C0J8Y6   C6K2U0   H6U7H0   A0A514KFM3   O12297   Q5DQ89   A0A0K2BMP6   A0A514KFI9   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   S6CE17   Q8JVQ9   A0A514KFL3   A0A514KHD6   A0A514KH02   S6BPH0   A0A514KFJ0   A0A514KFJ5   A0A514KFK4   A0A514KFK5   A0A514KFJ4   A0A514KFK1   Q8JVR1   A0A514KFJ6   P36299   E0AGY0   E3W5G2   A0A1Z2WUB3   A0A514KFK2   A0A514KFL5   A0A2H4KI18  

Pubmed

27619563    1662846    17023013    2174956    20229183    2841792    + More
3035066    2825819    10805807    3008432    11152504    1309909    7636969    8546012    25890036    23043168    2845226    18306032    19036814    21481551    25180686    22002680    25953186    19162099    22542271    16704791    17275120    22609354    27840394    12505636    10365166    26250391    20603153    26221765    8839428    1431811   

EMBL

KR061459    ALR84918.1    KX689261    AOT21923.1    X55980    X60056    + More
KT696544    AMB66492.1    DQ811785    ABG89300.1    AY587883    AAT00646.1    Z24675    AF302262    AAG30226.1    EU074218    FJ755618    ABU49663.1    ACN71200.1    AY335549    DQ201447    AAQ02626.1    ABC72418.1    JQ693056    AFZ88851.1    DQ811789    ABG89329.1    KX900397    ASV64317.1    DQ811788    ABG89323.1    HQ462571    ADY39744.1    M21627    X05598    X06371    AJ271965    M14878    Z35758    CAA84810.1    KX900396    KX900399    KX900400    KX900401    KX900403    KX900405    KX900406    KX900407    ASV64308.1    ASV64335.1    ASV64343.1    ASV64353.1    ASV64371.1    ASV64388.1    ASV64397.1    ASV64406.1    KX900404    ASV64379.1    KC962433    AGM75130.1    JQ693053    AFZ88848.1    JQ693055    AFZ88850.1    HM776941    AEM55570.1    KX900395    ASV64299.1    KX900408    KX900409    ASV64415.1    ASV64424.1    KP202848    AKA60058.1    Y00560    DQ443743    ABD97839.1    JQ693054    KU729220    KX499468    KX900393    KX900394    KX900402    MK166015    AFZ88849.1    AML22781.1    AQT01353.1    ASV64281.1    ASV64290.1    ASV64362.1    QCZ41128.1    KX900398    ASV64326.1    JQ700303    AFK10485.1    KF273109    AGW80452.1    AY884049    KC175340    KC175341    AAW57899.1    AFX81102.1    AFX81112.1    KX900411    ASV64442.1    JQ404409    AFG19730.1    DQ811787    ABG89312.1    KX900410    ASV64433.1    AY704916    AAU29609.1    AY884048    AAW57898.1    EU924790    EU924791    HQ450377    ACJ64180.1    ACJ64189.1    ADU17739.1    AB781790    BAN67923.1    JF682842    AEE69327.1    DQ517438    ABF72147.1    KY406735    ASV45152.1    AY864662    AAW66661.1    KP981644    AKA65834.1    AY390344    AAQ96368.1    KX083668    APQ31246.1    FJ009114    ACN60154.1    GU146061    ADB10854.1    EU856362    ACJ63247.1    AY864661    AAW66660.1    DQ112226    AAZ91441.1    AY390343    AAQ96367.1    AY899209    AAX18705.1    JQ404410    KY063616    KY063617    KY063618    AFG19744.1    ASB15743.1    ASB15753.1    ASB15761.1    JN856008    AEQ61972.1    LC190907    BAW32707.1    DQ811786    ABG89308.1    AF502583    AAO33711.1    AF104420    AAC96007.1    KR270796    AKV62759.1    EU856361    ACJ63236.1    AY436635    AAR11075.1    AY704917    AAU29610.1    HQ450376    ADU17730.1    GQ477367    ADB28912.1    FJ009115    ACN60155.1    GQ152141    ACS44222.1    JN624754    AFA51943.1    MK986745    QDI78404.1    Y13921    CAA74229.1    AY548235    AAT45197.1    KP849472    AKZ66477.1    MK986729    QDI78388.1    MK986742    QDI78401.1    MK986746    QDI78405.1    MK986739    QDI78398.1    MK986741    QDI78400.1    AB781788    BAN67905.1    AB086904    BAC01160.1    MK986735    QDI78394.1    MK986732    QDI78391.1    MK986736    QDI78395.1    AB781789    BAN67914.1    MK986738    QDI78397.1    MK986733    QDI78392.1    MK986734    QDI78393.1    MK986731    QDI78390.1    MK986730    QDI78389.1    MK986743    QDI78402.1    AB086903    BAC01158.1    MK986737    QDI78396.1    D13096    HQ012370    ADL71480.1    HQ392469    ADO39822.1    KY292377    ASB16892.1    MK986740    QDI78399.1    MK986744    QDI78403.1    KX722529    ASU62493.1   

Proteomes

UP000125818    UP000166023    UP000145148    UP000111647    UP000121388    UP000156732    + More
UP000158285    UP000137024    UP000113525    UP000001440    UP000123026    UP000166047    UP000098772    UP000158504    UP000131894    UP000155481    UP000165378    UP000119169    UP000149523    UP000115330    UP000106470    UP000153699    UP000129150    UP000129066    UP000164750    UP000174600    UP000128709    UP000113038   

PRIDE

P33464    P24412    P04135    P09175    P36299   

Pfam

PF01635   Corona_M

Interpro

IPR042551   ALPHA_CORONA_M
IPR002574   Corona_M

ProteinModelPortal

A0A0U2TVR6   A0A1D8ELQ6   P33464   A0A0Y0R0E2   Q0PL26   Q6PQ04   + More
P24412   Q9DY23   A7UJ02   Q7T713   M4I7F1   Q0PKZ1   A0A384VA81   Q0PL00   F1CNZ1   P04135   Q88514   A0A384V9Q6   A0A384V9L3   R9RZN0   M4I824   M4I7F5   G3CI08   A0A384V9E4   A0A384V9R1   A0A0E3GM58   P09175   Q1W2N8   A0A1S6KDW8   A0A384V9G9   I3QKR3   U3Q0B8   Q5FX57   A0A384VIC0   H9TEW2   Q0PL09   A0A384VGP5   Q64FR0   Q5FX58   B7T4B3   S6B903   F6M1R4   Q19NU4   A0A3S6JCJ2   Q5G1S5   A0A0D5ZYB2   Q6TPL0   A0A1L6BQB0   C0J8Y5   G8A505   B7T076   Q5G1S6   Q0ZVX1   Q6TPL1   Q5D578   H9TEX6   G8J7G9   A0A1L7NS55   Q0PL17   Q80RP1   Q9WKM6   A0A0K1RM39   B7T066   Q6T524   Q64FQ9   E7E031   D2WXM2   C0J8Y6   C6K2U0   H6U7H0   A0A514KFM3   O12297   Q5DQ89   A0A0K2BMP6   A0A514KFI9   A0A514KHE6   A0A514KH05   A0A514KFK0   A0A514KFM0   S6CE17   Q8JVQ9   A0A514KFL3   A0A514KHD6   A0A514KH02   S6BPH0   A0A514KFJ0   A0A514KFJ5   A0A514KFK4   A0A514KFK5   A0A514KFJ4   A0A514KFK1   Q8JVR1   A0A514KFJ6   P36299   E0AGY0   E3W5G2   A0A1Z2WUB3   A0A514KFK2   A0A514KFL5   A0A2H4KI18  

PDB

4FBH     E-value=3.67157,     Score=67