Strain

ROMANIA_PIG_2015_LT898435 (Region: Romania;  Strain: Porcine epidemic diarrhea virus isolate PEDV_ROMANIA_L01330-K25_15-02_2015 genome assembly, complete genome: monopartite.;  Date: 2015)

Gene

nucleocapsid protein

Description

Annotated in NCBI,  nucleocapsid protein

Location

LT898435(+):26370-27695

GenBank Accession

SNQ28049.1

Full name

Nucleoprotein      

CDS

ATGGCTTCTGTCAGTTTTCAGGATCGTGGCCGCAAACGGGTGCCATTATCCCTCTATGCCCCTCTTAGGGTTACTAATGACAAACCCCTTTCTAAGGTACTTGCAAATAATGCTGTACCCACTAATAAAGGAAATAAGGACCAGCAAATTGGATACTGGAATGAGCAAATTCGCTGGCGCATGCGCCGTGGTGAGCGAATTGAACAACCTTCCAATTGGCATTTCTACTACCTCGGAACAGGACCTCACGCCGACCTCCGCTATAGGACTCGTACTGAGGGTGTTTTCTGGGTTGCTAAAGAAGGCGCAAAGACTGAACCCACTAACCTGGGTGTCAGAAAGGCGTCTGAAAAGCCAATCATTCCAAATTTCTCTCAACAGCTTCCCAGCGTAGTTGAGATTGTTGAACCTAACACACCTCCTACTTCACGTGCAAATTCACGTAGCAGGAGTCGTGGTAATGGCAACAACAGGTCCAGATCTCCAAGTAACAACAGAGGCAATAACCAGTCCCGCGGTAATTCACAGAATCGTGGAAATAACCAGGGTCGTGGAGCTTCTCAGAACAGAGGAGGTAATAATAATAACAATAACAAGTCTCGTAACCAGTCCAAGAACAGAAACCAGTCAAATGACCGTGGTGGTGTAACATCACGCGATGATCTGGTGGCTGCTGTCAAGGATGCCCTTAAATCTTTGGGCATTGGCGAAAACCCTGACAAGCTTAAGCAACAGCAGAAGCCCAAACAGGAAAGGTTTGACAGCAGCGGCAAAAATACACCTAAGAAGAACAAATCCAGAGCCACTTCGAAAGAACGTGACCTTAAAGACATCCCAGAGTGGAGGAGAATTCCCAAGGGCGAAAATAGCGTAGCAGCTTGCTTCGGACCCAGGGGAGGCTTCAAAAATTTTGGAGATGCGGAATTTGTCGAAAAAGGTGTTGATGCCTCAGGCTATGCCCAGATCGCCAGTTTAGCACCAAATGTTGCAGCATTGCTCTTTGGTGGTAATGTGGCTGTTCGTGAGCTAGCGGACTCTTACGAGATTACATACAATTATGTAATGACTGTGCCAAAGTCTGATCCAAATGTAGAGCTTCTTGTTTCACAGGTGGATGCATTTAAAACTGGGAATGCAAAACCCCAGAGAAAGAAGGAAAAGAATAACAAGCGTGAAACCACGCAGCAGCTGAATGAAGATGCCATCTACGATGATGTGGGTTTGCCATCTGATTCGACTCATGCCAATTTGGAATGGGACACAGCTGTTGACGGTGGTGACACGGCCGTTGAAATTATCAACGAGATCTTCGATACAGGAAATTAA

Protein

MASVSFQDRGRKRVPLSLYAPLRVTNDKPLSKVLANNAVPTNKGNKDQQIGYWNEQIRWRMRRGERIEQPSNWHFYYLGTGPHADLRYRTRTEGVFWVAKEGAKTEPTNLGVRKASEKPIIPNFSQQLPSVVEIVEPNTPPTSRANSRSRSRGNGNNRSRSPSNNRGNNQSRGNSQNRGNNQGRGASQNRGGNNNNNNKSRNQSKNRNQSNDRGGVTSRDDLVAAVKDALKSLGIGENPDKLKQQQKPKQERFDSSGKNTPKKNKSRATSKERDLKDIPEWRRIPKGENSVAACFGPRGGFKNFGDAEFVEKGVDASGYAQIASLAPNVAALLFGGNVAVRELADSYEITYNYVMTVPKSDPNVELLVSQVDAFKTGNAKPQRKKEKNNKRETTQQLNEDAIYDDVGLPSDSTHANLEWDTAVDGGDTAVEIINEIFDTGN

Function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.

Uniprot

A0A238TMY4   A0A5J6SWI7   A0A075ED93   L0H8I5   A0A068JF91   A0A168SP43   + More
A0A3G2LYG4   A0A2P1DXC9   A0A068JFC5   A0A096XAF7   A0A1X9RV73   A0A0U2WPR7   A0A5J6AP34   A0A5K1KB31   A0A0U1YFU7   Q692L9   A0A1B1MR59   A7LKV4   G8GMX9   A0A0U2QCQ9   A0A075ECV7   G8GMX6   A0A2Z4ELF9   G8GMW7   G8GMW9   A0A5J6ANZ6   G8GMW1   A0A2K8IV16   A0A075EBL1   A0A4P8GMH2   A0A482F7J4   G8GMX4   A0A2U8QNF3   A0A1Z2TIW2   A0A5B8NE92   H9BVL2   A0A5J6SV63   A0A2S0S5B5   G9G5U2   A0A5J6AP94   A0A0U1YH00   K0F3Z8   A0A3G3C9B6   A0A482F8J1   A0A5J6APD4   K4NS05   A0A5J6AP53   A0A068JCX8   A0A068JC22  

Pubmed

25279722    23469356    25272273    27103490    25790462    26611909    + More
29879479    29540176    29770590    28589511    31350613    23166262   

EMBL

LT898436    LT898435    SNQ28020.1    SNQ28049.1    MK644602    QFG01698.1    + More
KJ645697    AID57043.1    KC196276    AGA94624.1    KF840543    AIE15969.1    KU252649    ANC68211.1    MG778701    AYN79040.1    MG837012    AVK78151.1    KF840552    AIE16014.1    KF760557    KJ526096    AHF20049.1    AJD07370.1    KU558701    KY679907    MH726368    ANY27035.1    ARQ84961.1    QCQ19838.1    KT323980    ALS35478.1    MH726373    QCQ19868.1    MH726381    QCQ19916.1    KJ857415    AJD09538.1    AY653206    AAT75300.1    KX168410    ANS71068.1    EU031893    ABS72127.1    JN173289    AET71263.1    KP641661    ALM31936.1    KJ645642    AID56713.1    JN173285    JN173286    JN255975    JN255976    AET71259.1    AET71260.1    AEW46025.1    AEW46026.1    MH107322    AWV57058.1    JN173277    JN173278    JN173280    JN173281    JN173282    JN173283    JN173290    JN173291    JN173295    JN255974    JN255982    JN255983    AET71251.1    AET71252.1    AET71254.1    AET71255.1    AET71256.1    AET71257.1    AET71264.1    AET71265.1    AET71269.1    AEW46024.1    AEW46032.1    AEW46033.1    JN173279    AET71253.1    MH726363    QCQ19808.1    JN173271    JN173272    JN173274    AET71245.1    AET71246.1    AET71248.1    KY619824    KY619825    ATJ03679.1    ATJ03680.1    KJ645683    AID56959.1    MH891587    QCO95414.1    MK032689    QBO24655.1    JN173284    AET71258.1    MH052689    AWM11502.1    KY963963    ASA69728.1    MK482396    MK482397    QDZ36666.1    QDZ36672.1    JQ081273    JQ081279    JQ081280    AFD98075.1    AFD98081.1    AFD98082.1    MK644605    QFG01716.1    MF118911    AWA82542.1    JN243758    AEV42923.1    MH726394    QCQ19994.1    KJ857421    AJD09544.1    JX406142    AFU07543.1    MG546688    AYP73638.1    MK032691    QBO24667.1    MH726396    MH726397    MH726398    QCQ20006.1    QCQ20012.1    QCQ20018.1    JX524137    AFV46348.1    MH726384    QCQ19934.1    KF840560    AIE16046.1    KF840559    AIE16045.1   

Proteomes

UP000278990    UP000280596    UP000097949    UP000170972    UP000105572    UP000117616    + More
UP000135702    UP000138881    UP000103873    UP000150601    UP000174771    UP000100611   

Pfam

PF00937   Corona_nucleoca

Interpro

IPR037195   Nucleocapsid_N
IPR042548   ALPHA_CORONA_NCAP
IPR001218   Corona_nucleocap
IPR037179   Nucleocapsid_C

SUPFAM

SSF103068   SSF103068
SSF110304   SSF110304

ProteinModelPortal

A0A238TMY4   A0A5J6SWI7   A0A075ED93   L0H8I5   A0A068JF91   A0A168SP43   + More
A0A3G2LYG4   A0A2P1DXC9   A0A068JFC5   A0A096XAF7   A0A1X9RV73   A0A0U2WPR7   A0A5J6AP34   A0A5K1KB31   A0A0U1YFU7   Q692L9   A0A1B1MR59   A7LKV4   G8GMX9   A0A0U2QCQ9   A0A075ECV7   G8GMX6   A0A2Z4ELF9   G8GMW7   G8GMW9   A0A5J6ANZ6   G8GMW1   A0A2K8IV16   A0A075EBL1   A0A4P8GMH2   A0A482F7J4   G8GMX4   A0A2U8QNF3   A0A1Z2TIW2   A0A5B8NE92   H9BVL2   A0A5J6SV63   A0A2S0S5B5   G9G5U2   A0A5J6AP94   A0A0U1YH00   K0F3Z8   A0A3G3C9B6   A0A482F8J1   A0A5J6APD4   K4NS05   A0A5J6AP53   A0A068JCX8   A0A068JC22  

PDB

5N4K     E-value=6.04631e-36,     Score=379