Strain

GERMANY_PIG_2015_LT898439 (Region: Germany;  Strain: Porcine epidemic diarrhea virus isolate PEDV_GER_L01059-K07_15-01_2015 genome assembly, complete genome: monopartite.;  Date: 2015)

Gene

nucleocapsid protein

Description

Annotated in NCBI,  nucleocapsid protein

Location

LT898439(+):26370-27695

GenBank Accession

SNQ28042.1

Full name

Nucleoprotein      

CDS

ATGGCTTCTGTCAGTTTTCAGGATCGTGGCCGCAAACGGGTGCCATTATCCCTCTATGCCCCTCTTAGGGTTACTAATGGCAAACCCCTTTCTAAGGTACTTGCAAATAATGCTGTACCCACTAATAAAGGAAATAAGGACCAGCAAATTGGATACTGGAATGAGCAAATTCGCTGGCGCATGCGCCGTGGTGAGCGAATTGAACAACCTTCCAATTGGCATTTCTACTACCTCGGAACAGGACCTCACGCCGACCTCCGCTATAGGACTCGTACTGAGGGTGTTTTCTGGGTTGCTAAAGAAGGCGCAAAGACTGAACCCACTAACCTGGGTGTCAGAAAGGCGTCTGAAAAGCCAATCATTCCAAATTTCTCTCAACAGCTTCCCAGCGTAGTTGAGATTGTTGAACCTAACACACCTCCTACTTCACGTGCAAATTCACGTAGCAGGAGTCGTGGTAATGGCAACAACAGGTCCAGATCTCCAAGTAACAACAGAGGCAATAACCAGTCCCGCGGTAATTCACAGAATCGTGGAAATAACCAGGGTCGTGGAGCTTCTCAGAACAGAGGAGGCAATAATAATAACAATAACAAGTCTCGTAACCAGTCCAAGAACAGAAACCAGTCAAATGACCGTGGTGGTGTAACATCACGCGATGATCTGGTGGCTGCTGTCAAGGATGCCCTTAAATCTTTGGGCATTGGCGAAAACCCTGACAAGCTTAAGCAACAGCAGAAGCCCAAACAGGAAAGGTCTGACAGCAGCGGCAAAAATACACCTAAGAAGAACAAATCCAGAGCCACTTCGAAAGAACGTGACCTTAAAGACATCCCAGAGTGGAGGAGAATTCCCAAGGGCGAAAATAGCGTAGCAGCTTGCTTCGGACCCAGGGGAGGCTTCAAAAATTTTGGAGATGCGGAATTTGTCGAAAAAGGTGTTGATGCCTCAGGCTATGCCCAGATCGCCAGTTTAGCACCAAATGTTGCAGCATTGCTCTTTGGTGGTAATGTGGCTGTTCGTGAGCTAGCGGACTCTTACGAGATTACATACAATTATGTAATGACTGTGCCAAAGTCTGATCCAAATGTAGAGCTTCTTGTTTCACAGGTGGATGCATTTAAAACTGGGAATGCAAAACCCCAGAGAAAGAAGGAAAAGAAGAACAAGCGTGAAACCACGCAGCAGCTGAATGAAGATGCCATCTACGATGATGTGGGTTTGCCATCTGATTCGACTCATGCCAATTTGGAATGGGACACAGCTGTTGACGGTGGTGACACGGCCGTTGAAATTATCAACGAGATCTTCGATACAGGAAATTAA

Protein

MASVSFQDRGRKRVPLSLYAPLRVTNGKPLSKVLANNAVPTNKGNKDQQIGYWNEQIRWRMRRGERIEQPSNWHFYYLGTGPHADLRYRTRTEGVFWVAKEGAKTEPTNLGVRKASEKPIIPNFSQQLPSVVEIVEPNTPPTSRANSRSRSRGNGNNRSRSPSNNRGNNQSRGNSQNRGNNQGRGASQNRGGNNNNNNKSRNQSKNRNQSNDRGGVTSRDDLVAAVKDALKSLGIGENPDKLKQQQKPKQERSDSSGKNTPKKNKSRATSKERDLKDIPEWRRIPKGENSVAACFGPRGGFKNFGDAEFVEKGVDASGYAQIASLAPNVAALLFGGNVAVRELADSYEITYNYVMTVPKSDPNVELLVSQVDAFKTGNAKPQRKKEKKNKRETTQQLNEDAIYDDVGLPSDSTHANLEWDTAVDGGDTAVEIINEIFDTGN

Function

Packages the positive strand viral genome RNA into a helical ribonucleocapsid (RNP) and plays a fundamental role during virion assembly through its interactions with the viral genome and membrane protein M. Plays an important role in enhancing the efficiency of subgenomic viral RNA transcription as well as viral replication.

Subunit

Homooligomer. Both monomeric and oligomeric forms interact with RNA. Interacts with protein M. Interacts with NSP3; this interaction serves to tether the genome to the newly translated replicase-transcriptase complex at a very early stage of infection.

Uniprot

A0A238TMI6   A0A168SP43   A0A238TM58   A0A3G2LYG4   A0A0F6R9J8   A0A5J6SWI7   + More
A0A0U3HGI9   A0A238TMY4   A0A345YTW0   A0A2P1DXC9   A0A5J6AP69   A0A1U9WZ07   A0A238TQG4   A0A096XAF7   A0A0A8LFI9   X5CR25   A0A1S6L952   A0A0E3TJA8   A0A3Q8TM10   A0A068JFC5   F5CIA0   A0A4P8YSC7   A0A1L3KIW2   A0A068JFD4   A0A1S6QMK2   G8GMX6   A0A2S0S5C2   A0A0U2WPR7   A0A5J6AP34   A0A1X9RV73   K0FAU6   W8GL04   A0A075ED93   A0A2I6DZH5   A0A3S8TLR7   A0A068JFD0   X2F0T5   A0A0B4ZZG8   A0A142C7C3   A0A2S0S5A3   H9A5G4   A0A191TBR6   A0A4D6FU77   A0A1L6K604   A0A238TML0   A0A4D6GHU4   A0A5B8YU42   A0A068JF81   A0A5K1KB31   A0A3S8TLP7   A0A3S8Z5F8   A0A068JF89   A0A023J7B8   A0A1X9Q890   G8GMX9   A0A075EB78   A0A142C7C6   A0A1B1MR59   A7LKV4   A0A2U3TMT9   G8GMW7   A0A068JF77   Q692L9   L0H8I5   W8GYS6   A0A0C5L1M8   A0A1X9Q8A0   A0A2S0S5D8   A0A0P0TE87   G8GMX7   A0A075ECV7   G8GMW9   A0A5J6ANZ6   B7UCM9   A0A0K1RL77   A0A2P1DXE3   A0A076L8M5   B7UCM1   A0A0U1YGD3   A0A2S0S5D1   A0A0S3MSK5   A0A0C5KQR9   A0A5J6SUP1   W8GQF3   K0FB21   A0A1X9PY47   A0A0U1VF12   G8GMX4   A0A2Z4ELF9   A0A075EBH4   A0A068JF91   W8GYV4   A0A0U2QCQ9   A0A411E5Q1   A0A0U2C6P5   A0A068JF87   A0A482F7J4   A0A0S3MR21   W8GTV6   A0A2U8QNF3  

Pubmed

27103490    26044419    27056240    25790462    24818713    25999551    + More
25272273    25694517    30593385    27880757    26611909    25279722    24744324    23151819    26512689    23469356    23381394    26477934    29879479    29770590   

EMBL

LT898439    LT900499    SNQ28042.1    SNT95663.1    KU252649    ANC68211.1    + More
LT898421    LT898431    SNQ27912.1    SNQ27983.1    MG778701    AYN79040.1    KR011756    LT898408    LT898415    LT898413    LT898414    LT898411    LT898416    LT898418    LT898423    LT898409    LT898412    LT898410    LT898432    LT898425    LT898427    LT898430    LT898433    LT898426    LT898438    LT898440    LT898441    LT898443    LT898446    LT898444    LT898417    LT900498    LT900500    LT900502    LT900501    AKE47382.1    SNQ27891.1    SNQ27897.1    SNQ27903.1    SNQ27916.1    SNQ27921.1    SNQ27928.1    SNQ27938.1    SNQ27939.1    SNQ27945.1    SNQ27959.1    SNQ27965.1    SNQ27971.1    SNQ27979.1    SNQ27989.1    SNQ27995.1    SNQ28001.1    SNQ28015.1    SNQ28026.1    SNQ28036.1    SNQ28055.1    SNQ28061.1    SNQ28068.1    SNQ28080.1    SNQ28086.1    SNT95657.1    SNT95669.1    SNT95675.1    SNT95681.1    MK644602    QFG01698.1    KU297956    ALU34116.1    LT898436    LT898435    SNQ28020.1    SNQ28049.1    MF807952    AXK47362.1    MG837012    AVK78151.1    MH726383    QCQ19928.1    KY111278    AQY61723.1    LT898420    SNQ27953.1    KF760557    KJ526096    AHF20049.1    AJD07370.1    LM645057    CDW77209.1    KJ196348    AHW40034.1    KX550281    AQT33898.1    KR003452    AKC34876.1    MH061340    AZL47220.1    KF840552    AIE16014.1    JF700126    KM609213    KT199103    KR153325    KR153326    KX064280    KX981440    KX812523    KX016034    KY007140    MF118913    MH061337    MH061343    MH117940    MK250953    LM645058    MH726369    MH726380    MK409657    MK409658    MK409659    LT898447    AEE38484.1    AJP67460.1    ALP06214.1    AMS37102.1    AMS37109.1    AND76941.1    APH81310.1    AQW35011.1    ARJ54150.1    ATG31104.1    AWA82544.1    AZL47202.1    AZL47238.1    AZP03047.1    AZS27729.1    CDW77217.1    QCQ19844.1    QCQ19910.1    QEE80063.1    QEE80069.1    QEE80075.1    SNQ28092.1    MH726372    MH726382    MK138353    MK422160    MK577661    QCQ19862.1    QCQ19922.1    QCT24241.1    QEA72160.1    QEQ76229.1    KX883635    APG77340.1    KF840554    AIE16024.1    KX812524    AQW35017.1    JN173285    JN173286    JN255975    JN255976    AET71259.1    AET71260.1    AEW46025.1    AEW46026.1    MF118920    AWA82551.1    KT323980    ALS35478.1    MH726373    QCQ19868.1    KU558701    KY679907    MH726368    ANY27035.1    ARQ84961.1    QCQ19838.1    JX406143    AFU07544.1    KF994793    AHK25043.1    KJ645697    AID57043.1    MF375374    MH061336    AUJ79488.1    AZL47196.1    MH061341    AZL47226.1    KF840553    AIE16019.1    KJ020932    AHM88221.1    KM604665    AJD80652.1    KT799997    AMP46775.1    MF118914    MF118917    AWA82545.1    AWA82548.1    JN825712    KF468756    KF994804    KR818833    KU975389    KX066126    KX580953    MF118912    AFC98507.1    AGZ04447.1    AHK25054.1    ALL27312.1    AMR60837.1    APD70938.1    AQK38172.1    AWA82543.1    KU982974    ANI85780.1    MK606369    QCB65310.1    KY070587    APR64499.1    LT898445    SNQ28074.1    MK140811    MK140812    MK140813    MK140814    QCC26585.1    QCC26592.1    QCC26599.1    QCC26606.1    MH726377    MH726378    MH726379    MK841495    QCQ19892.1    QCQ19898.1    QCQ19904.1    QED40661.1    KF840539    AIE15949.1    MH726381    QCQ19916.1    MH061338    AZL47208.1    MH056657    AZN28591.1    KF840542    AIE15964.1    KF761675    KT021227    KT021228    AHG97489.1    ALM09362.1    ALM09368.1    KX532180    KX532182    KX532183    ARQ18612.1    ARQ18622.1    ARQ18627.1    JN173289    AET71263.1    KJ645643    AID56719.1    KT800000    AMP46778.1    KX168410    ANS71068.1    EU031893    ABS72127.1    MF118916    MH726406    MH726407    AWA82547.1    QCQ20066.1    QCQ20072.1    JN173277    JN173278    JN173280    JN173281    JN173282    JN173283    JN173290    JN173291    JN173295    JN255974    JN255982    JN255983    AET71251.1    AET71252.1    AET71254.1    AET71255.1    AET71256.1    AET71257.1    AET71264.1    AET71265.1    AET71269.1    AEW46024.1    AEW46032.1    AEW46033.1    KF840538    AIE15944.1    AY653206    AAT75300.1    KC196276    AGA94624.1    KF994789    AHK25039.1    KM609203    AJP67400.1    KX532181    ARQ18617.1    MF118918    AWA82549.1    KT021232    KT021233    ALM09392.1    ALM09398.1    JN173287    JN255977    JN255978    AET71261.1    AEW46027.1    AEW46028.1    KJ645642    AID56713.1    JN173279    AET71253.1    MH726363    QCQ19808.1    FJ473393    ACK77286.1    KR809885    AKV62623.1    MG837011    AVK78145.1    KJ777677    KJ777678    AIJ01345.1    FJ473389    FJ473390    ACK77278.1    ACK77280.1    KJ857412    AJD09535.1    MF118915    AWA82546.1    LC063822    BAT33189.1    KM609212    AJP67454.1    MK644601    QFG01692.1    KF994806    AHK25056.1    JX406136    AFU07537.1    KY793536    ARQ03273.1    KJ857409    AJD09532.1    JN173284    AET71258.1    MH107322    AWV57058.1    KJ645673    KM077139    AID56899.1    AIK28712.1    KF840543    AIE15969.1    KF994799    AHK25049.1    KP641661    ALM31936.1    MH243319    QBA57562.1    KR265760    AKJ21711.1    KF840541    AIE15959.1    MK032689    QBO24655.1    LC063826    BAT33213.1    KF994795    AHK25045.1    MH052689    AWM11502.1   

Proteomes

UP000269355    UP000274124    UP000105572    UP000267609    UP000268721    UP000100204    + More
UP000267271    UP000267306    UP000270191    UP000270497    UP000270545    UP000271078    UP000271448    UP000272790    UP000273819    UP000274353    UP000274834    UP000274992    UP000275549    UP000275656    UP000275831    UP000276052    UP000276298    UP000276964    UP000277020    UP000277354    UP000277927    UP000278039    UP000278495    UP000278554    UP000279022    UP000280517    UP000281047    UP000281935    UP000132054    UP000278990    UP000280596    UP000269867    UP000117616    UP000135702    UP000138211    UP000129155    UP000166734    UP000097091    UP000134050    UP000142872    UP000155002    UP000271135    UP000138881    UP000097949    UP000141838    UP000133157    UP000141524    UP000281631    UP000111801    UP000113720    UP000152961    UP000141497    UP000170972    UP000122204    UP000141943    UP000167996    UP000150601    UP000117357    UP000096940    UP000180355    UP000137135    UP000145028    UP000102715    UP000135367    UP000103873    UP000154704    UP000146214   

Pfam

PF00937   Corona_nucleoca

Interpro

IPR042548   ALPHA_CORONA_NCAP
IPR037195   Nucleocapsid_N
IPR037179   Nucleocapsid_C
IPR001218   Corona_nucleocap

SUPFAM

SSF103068   SSF103068
SSF110304   SSF110304

ProteinModelPortal

A0A238TMI6   A0A168SP43   A0A238TM58   A0A3G2LYG4   A0A0F6R9J8   A0A5J6SWI7   + More
A0A0U3HGI9   A0A238TMY4   A0A345YTW0   A0A2P1DXC9   A0A5J6AP69   A0A1U9WZ07   A0A238TQG4   A0A096XAF7   A0A0A8LFI9   X5CR25   A0A1S6L952   A0A0E3TJA8   A0A3Q8TM10   A0A068JFC5   F5CIA0   A0A4P8YSC7   A0A1L3KIW2   A0A068JFD4   A0A1S6QMK2   G8GMX6   A0A2S0S5C2   A0A0U2WPR7   A0A5J6AP34   A0A1X9RV73   K0FAU6   W8GL04   A0A075ED93   A0A2I6DZH5   A0A3S8TLR7   A0A068JFD0   X2F0T5   A0A0B4ZZG8   A0A142C7C3   A0A2S0S5A3   H9A5G4   A0A191TBR6   A0A4D6FU77   A0A1L6K604   A0A238TML0   A0A4D6GHU4   A0A5B8YU42   A0A068JF81   A0A5K1KB31   A0A3S8TLP7   A0A3S8Z5F8   A0A068JF89   A0A023J7B8   A0A1X9Q890   G8GMX9   A0A075EB78   A0A142C7C6   A0A1B1MR59   A7LKV4   A0A2U3TMT9   G8GMW7   A0A068JF77   Q692L9   L0H8I5   W8GYS6   A0A0C5L1M8   A0A1X9Q8A0   A0A2S0S5D8   A0A0P0TE87   G8GMX7   A0A075ECV7   G8GMW9   A0A5J6ANZ6   B7UCM9   A0A0K1RL77   A0A2P1DXE3   A0A076L8M5   B7UCM1   A0A0U1YGD3   A0A2S0S5D1   A0A0S3MSK5   A0A0C5KQR9   A0A5J6SUP1   W8GQF3   K0FB21   A0A1X9PY47   A0A0U1VF12   G8GMX4   A0A2Z4ELF9   A0A075EBH4   A0A068JF91   W8GYV4   A0A0U2QCQ9   A0A411E5Q1   A0A0U2C6P5   A0A068JF87   A0A482F7J4   A0A0S3MR21   W8GTV6   A0A2U8QNF3  

PDB

5N4K     E-value=6.04631e-36,     Score=379